... atrans-conformation, with the nitrogen-bond hydrogenand the carbonylic oxygen oriented in opposite direc-tions) (Figure 3D). SAHA, consistent with its non-specificinhibitory activity on HDACs ... Federico Mele, Rome, Italy, and Ms. Dora Pinto, ibidem, for technical help, Ms. Maria Grazia Bedetti, ibidem, for admin-istrative support, and Dr. Mark Kanieff, ibidem, for the linguistic revision. ... virus inte-grase inhibitors efficiently suppress feline immunodeficiencyvirus replication in vitro and provide a rationale to redesignantiretroviral treatment for feline AIDS. Retrovirology 2007,4:79.21....