Báo cáo y học: "Dynamic instability of the major urinary protein gene family revealed by genomic and phenotypic comparisons between C57 and 129 strain mice" ppt
Báo cáo y học: "Dynamic instability of the major urinary protein gene family revealed by genomic and phenotypic comparisons between C57 and 129 strain mice" ppt
... loci. The timing of the oldest divergence amongst the lineage of these genes is esti-mated at 11.2-22.4 Mya between genes 16 and 19; the timing of the minimum at 4.4-8.8 Mya between genes 18 and ... about the evolution of the Mup gene family, in particular regarding the relationship between urinary MUPs and non -urinary MUPs, and between those MUPs that do and do not exhibit sexuallydimorphic ... again thereis no evidence for secretion of the protein. DiscussionThis is the first in depth analysis of the Mup gene clusters of two distinct strains of mice, strengthened by resolution of the distinct...
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Báo cáo y học: "Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects" pptx
... thissubgroup of infected persons [4] Since in the absence of anti-retroviral therapy (ART), the HIV-1 replication capac-ity (RC) is largely related to the efficiency of viral entry[5,6]-, the selective ... recognized by this broad neutralizing antibody on the gp120 surface [34].Identification of rare mutationsWhen the amino acid entropy of positively selected siteswas studied, the majority of substitutions ... view of the interaction site between gp120 of patient F and the IgGb12 heavy chain (pdb code NY7)). Visualization of the dN/dS score (the posterior mean value derived from the Empirical Bayes...
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Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt
... and the phosphates of the capstructure, or of the backbone of the RNA, thereby reducing the affinity of eIF4E for its ligand and potentially opening up the cap-bindingcleft.5354 G. C. Scheper and ... eIF4Ephosphorylation will be determined by two factors. The firstis the state of activation of the Erk or p38 MAP kinasepathways, which regulate the activity of Mnk1. The secondis the level of eIF4F ... also be a very valuable tool instudying the functional effects of eIF4E phosphorylation. The Mnks may of course have other roles in cellularphysiology, and knock-outs of these enzymes (single...
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Báo cáo y học: "Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice" doc
... mice were pro-duced by a deletion in the IL-10 gene in a cross of C57BL/6 × 129/ Ola (originally provided by W Müller, Institute of Genetics, Cologne, Germany). They were further back-crossed ... scores.Among mice of the QD strain, individuals that subsequentlydeveloped cyanosis lost as much as 25% of their bodyweight within a few days after the onset of respiratorysymptoms (Fig. 1). Major weight ... scores. However, the symp-toms in these strains did not proceed in relapses as theydid in the QD and B10.Q mice, and therefore resulted in alower mean score than for the other strains (Fig. 1c).Table...
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Báo cáo y học: "Polarized expression of the membrane ASP protein derived from HIV-1 antisense transcription in T cells" potx
... replace the wild type segment. The pNL4.3LucE-R-vector (containing the luciferase reporter gene and deficient for Env and Vprsynthesis [26]) was generously provided by Dr N.R.Landau. The pNL4.3AsLucE-R-vector ... characterize the ASP protein, its expression and localization were analyzed in Jurkat cells. Analysis of itsamino acid sequence reveals a highly hydrophobic protein. Hydropathy and immunogenicity plots ... because theyare usually poorly abundant. All these issues concerningmembrane proteins explain the great disparity between current knowledge of soluble versus membrane proteins.In this paper, by...
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Báo cáo khoa học: Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis Functional analysis of the promoter identifies a calcium sensitive region required for basal activity doc
... 1).Identification of putative regulatory elementswithin the xMGP gene promoter The 5 ¢ flanking sequence of the xMGP gene is typ ical for aRNA polymerase II transcribed gene. Immediatelyupstream from the ... (including the vitamin D, retinoic acid and thyroid hormone receptors)did not modulate the activity of the )949LUC reportersignificantly, either in presence or absence of the cognateligands (N. ... respectively) with the unlabeled )180/)36 bp (lanes 1 and 7) and the )134/)36 bp(lanes 3 a nd 9) fragments from the xMGP gene promoteralmost completely prevented the formation of the DNA-protein...
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Báo cáo y học: "Dynamic models of immune responses: what is the ideal level of detail" pptx
... correlation between virulenceandgrowthrateofthepathogen[18,19],theygiveimportantinsightintopathogenesis.Models of infection pathogenesis The complexity of the models increases when they aim to ... complexity of these models is dependent on the number of components and the temporal resolution in the model. We comment on the specificuse of simple and complex models in the study of the progression ... Nevertheless, to study the pathogenesis of an infection we need todevelop models describing the dynamics of the immune components involved in the progression of the disease. Incorporation of the...
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Báo cáo y học: "Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition" docx
... prototype model and the previous models developed by others contain only three metabolic pathways, namely, the glycolysis pathway, the pentose phosphate pathway and the nucleotide metabolic pathway. ... Schubert D: The complex of band 3 protein of the human erythrocyte membrane and glyceraldehyde-3-phosphate dehydrogenase: stoichiometry and competition by aldolase. Biochim Biophys Acta 2002, ... key enzymes in glycolysis bind to the Band III pro-tein, an abundant membrane protein in the human RBC[38-40]. The interaction between glycolytic enzymes and Band III varies depending on the...
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Báo cáo y học: "Anticancer Activity of the PR Domain of Tumor Suppressor RIZ1"
... confirmed by Western blot described below; and the cell death rate was exam-ined by the trypan blue method after 24 and 48 hr of transfections, respectively. Western blot of PR domain The expression ... expression of the PR domain was examined after 24 hr of transfection with pcDNA/HisMax/PR and the empty vector, respectively. Supernatants (30 g) of the cell lysates were separated by SDS-PAGE and ... levels of selected target genes using Origene qPCR Cancer Survey Panels (Rockville, Maryland, USA) has been reported previously [21]. Briefly, the primers and the TaqMan probe for gene RIZ...
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Báo cáo y học: " Experimental ablation of the pancreas with high intensity focused ultrasound (HIFU) in a porcine model"
... During the therapeutic process, real-time estimation of the therapeutic effect was carried out by the computer system through the graphic changes in the target field and the hyperecho of the ... consisting primarily of lymphocytes and monocytes sometimes with small number of eosinocytes, were seen between the necrotic and normal zones. In addi-tion, hyperplasia of fibroblasts and collagen ... efficacy and safety. To evaluate the rela-tionship between HIFU energy and pancreas histol-ogy, a preclinical in vivo study was conducted in swine demons t rat ing the feasibility and safety of...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămchuyên đề điện xoay chiều theo dạngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ