Báo cáo y học: "Shaken not stirred: a global research cocktail served in Hinxton" pot
Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"
... medical emergency contacts outside hospitals in Norway - a prospective population based study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2010 18:9.Submit your next manuscript ... score was in the analyses cate-gorised as NACA 0-1 , indicating a patient either withno symptoms/injuries or in no need of medical treat-ment, NACA 2-3 , indicating need of medical helpwhere value ... possibleNACA 5 Acute vital (life threatening) dangerNACA 6 Acute cardiac or respiratory arrestNACA 7 DeathZakariassen et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2010,...
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Báo cáo y học: "Do we need a critical care ultrasound certification program? Implications from an Australian medical-legal perspective"
... cation program? Implications from an Australian medical-legal perspectiveStephen J Huang and Anthony S McLean*VIEWPOINT*Correspondence: mcleana@med.usyd.edu.auDepartment of Critical Care Medicine, ... standards, both certifi -cation processes are provided by a single profes sional body that is well-recognized and widely accepted in Australia and New Zealand, the Australasian Society of Ultrasound ... this paper, we take a slightly di erent perspective, from an Australian medical-legal viewpoint, to argue for the need to implement a critical care ultrasound certi cation program. We examine...
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Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"
... improvesurvival?There are few data on the effect of treatment of AF on mortality in ICU patients. A meta-analysis in non-ICU patients showedthat class IA, class IC and class III antiarrhythmic agents areequally ... placebo[91,94-97]. A meta-analysis showed that class IA, class ICand class III antiarrhythmic agents are equally effective in obtaining SR [98]. Meta-analyses comparing amiodaronewith class IC antiarrythmic ... Connolly SJ: Evidence-based analysis of amiodarone efficacyand safety. Circulation 1999, 100:2025-2034.115. Hughes M, Binning A: Intravenous amiodarone in intensive care. Time for a reappraisal? Intensive...
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Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf
... suggest that certain enzymes, andtherefore the corresponding genes of the A2 0 1A biosyn-thetic pathway, may be related to their counterparts of the puromycin and hygromycin A biosynthetic pathways,respectively. The ... Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A2 0 1A from Streptomyces capreolus Irene Saugar*, Eloı´sa Sanz*, Miguel A ´ngel ... in oleandomycin biosynthesis [40].Gene analyses and enzymatic assays suggest that the biosynthetic pathways of the aminonucleoside moieties of A2 0 1A and puromycin start from ATP [6]. This metaboliteshould...
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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... splicing inhibition by tetracycline is n egligible (Fig. 2). The sixfold stron ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by thesubstitution, ... [31].RESULTSErythromycin, Cl-tetracycline and streptomycin inhibit nuclear splicing in vitro The effects of eight different antibiotics (the aminoglycoside,kanamycin, the a minocyclitol glycoside, streptomycin, ... RNA by 9%only (lane 3). T he other three antibiotics, Cl -tetracycline,streptomycin and erythromycin, are clearly inhibitors of nuclear pre-mRNA splicing, as indicated by a largereduction in...
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Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx
... Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes Role of oxidative stressDiego Ingrosso1,2, Amelia Cimmino1, Stefania D’Angelo1, ... enzymeassays, and referred to as Ôbuoyant fractionÕ and ÔdensefractionÕ. Pyruvate kinase (PK) activity was measured, as a cell-age marker, in individual erythrocyte populations.Diagnostic evaluation ... such as ankyrinand bands 4.1 and 4.2, as well as the integral membrane protein band 3 (AE1; the anion transporter) [6]. In thisrespect, asparaginyl deamidation has been shown to play a role in...
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Báo cáo y học: "Hypoxia: not merely a regulator of angiogenesis" ppt
... Giatromanolaki A, Sivridis E, Maltezos E, Athanassou N, Papa-zoglou D, Gatter KC, Harris AL, Koukourakis MI: Upregulatedhypoxia inducible factor-1alpha and -2alpha pathway inrheumatoid arthritis ... hydroxylation of asparaginyl residues within thesubunit [5]. The critical dependence of prolyl andasparaginyl hydroxylation on oxygen means that, underconditions of hypoxia, HIF-α accumulates ... are an inflamed, heavily infiltrated andthickened synovium, with pannus formation and subsequentinvasion and destruction of cartilage and bone. Oneconsequence of synovial hyperplasia in RA is...
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Báo cáo y học: "New data favouring that neurotrophins are of importance in arthritis" pot
... present in the synovial tissue and on chondrocytes. The importance of neurotrophins in joints should be further studied,including examinations on the efficacy of interfering with theireffects in ... in fibroblast-like synoviocytes, as seen by ELISAanalysis on culture supernatant. The authors concluded that infiltrating T lymphocytes and myeloid cells are the mainsources of NGF in the inflamed ... beenconsidered of importance in various types of inflammatoryconditions. In particular, NGF has been detected at highlevels in regions with inflammation. Accordingly, there are high levels of NGF in the...
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Báo cáo y học: " Large scale comparison of global gene expression patterns in human and mous" pot
... Zheng-Bradley et al.: Large scale comparison of global gene expression patterns in human and mouse. Genome Biology2010 11:R124.Zheng-Bradley et al. Genome Biology 2010, 11:R124http://genomebiology.com/content/11/12/R124Page ... human and mouse; this may at least partiallyexplain the conservation of global gene expression pat-terns we observed in this study.Materials and methodsCreating an integrated mouse gene expression ... linesAll51015All0Windows of genes sorted by expression varianceFigure 5 Percent age of sha red mouse and human orthologs in windows of 600 genes sorted by expression variance (descendingfrom...
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Báo cáo y học: " P300 amplitude is insensitive to working memory load in schizophrenia" potx
... ARTICLE Open Access P300 amplitude is insensitive to working memory load in schizophreniaPablo A Gaspar1,2*, Sergio Ruiz3,4,5, Francisco Zamorano5, Marcela Altayó5, Carolina Pérez5, Conrado ... dependent on attention, working memory load, and task difficulty. The difficulty of our task may par-tially account for the diminished P300 in our SZ subjects,as they showed a lower hit rate ... Thus, the study of WMmechanisms and their impairments in SZ might contri-bute to unveil some of the underlying affected mechan-isms in this disease. Specifically, our aim is to analyzethe pattern...
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Báo cáo y học: "Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen " pdf
... domain has ATPase activity and facilitates self-oli-gomerization. At the amino-terminal a protein-protein inter-action mediating caspase-recruitment domain (CARD) is localized (one CARD domain ... theincreasing number of antibiotic- resistant bacteria, and the emergence of new pulmonary pathogens into account,an exact analysis of molecular mechanisms of disease ismandatory to form a rational ... IRAK1, IRAK2, TRAF6 as well as NIK (NF-κB-inducing kinase), TAB2 (transform-ing growth factor-β activated kinase binding protein) and TAK1 (transforming growth factor-β activated kinase) in S....
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Báo cáo y học: "Bench-to-bedside review: Inhaled nitric oxide therapy in adults" pot
... vasoconstriction; iNO = inhaled nitric oxide; iNOS = inducible nitric oxide synthase; NO = nitric oxide; NO2= nitrogen dioxide; NOS = nitric oxide synthase; PaO2/FiO2=arterial partial pressure of oxygen/fraction ... of inhaled nitric oxide in British intensive therapy units. Br J Anaesth 1997, 78:696-700.5. Beloucif S: A European survey of the use of inhaled nitric oxide in the ICU. Working Group on Inhaled ... 1Studies of inhaled nitric oxide in adult patients with acute lung injury/acute respiratory distress syndromeNumber Interventionof patients/ Inhaled Primary Secondary Study Year centres...
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Báo cáo y học: " Recently published papers: A review of novel strategies in the prevention of hospital-acquired infections, the ability of intensivists to perform echocardiography, and the benefit of polymyxin B haemoperfusion in abdominal sepsis" pot
... of < /b> hospital-acquired < /b> infections, < /b> the < /b> ability < /b> of< /b> intensivists < /b> to < /b> perform < /b> echocardiography, < /b> and < /b> the < /b> benefit < /b> of< /b> polymyxin < /b> B haemoperfusion in < /b> abdominal sepsisJames Hayward and < /b> Richard VennDepartment ... with a < /b> high affinity for endotoxin. Haemoperfusion was performed using haemoperfusion polystyrene fibres withbound polymyxin < /b> B. The < /b> study was stopped early becausethere was a < /b> signal of < /b> decreased ... ICUpractice of < /b> daily sedation holds and < /b> therapy as per the< /b> primary care team versus daily sedation holds with specificearly exercise and < /b> mobilisation (physical and < /b> occupationaltherapy). In < /b> their...
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Báo cáo y học: "Scandinavian Emergency Medicine – A toddler steadily walking but still not running" potx
... together as a discipline, I hope thatwe can make this wish come true and, at the same time,make emergency medicine an established part of everyday medicine in Scandinavia as well as all over ... results. Anyonewho works in the field of pre-hospital care has knowledgeof the Utstein formulas. This little monastery name in Sta-vanger serves as a symbol of quality work, and manypapers drafted ... recent25th anniversary of The Journal of Emergency Medicine, which is that most of the articles in the first issue are rele-vant to the practitioner today meaning year 2033 for thisyoungster. By working...
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Báo cáo y học: "Shaken not stirred: a global research cocktail served in Hinxton" pot
... identifying DNA-binding sites fortranscription factors by chromatin immunoprecipitationfollowed by microarray analysis (ChIP-chip) to gain insightinto regulatory networks. Stewart MacArthur (LawrenceBerkeley ... lines. He and his colleagues alsodevised an elegant screen for components of the Jun N-terminal kinase (JNK) pathway by targeting all kinases andphosphatases by RNAi in cells producing fluorescence ... (LawrenceBerkeley National Laboratory, Berkeley, USA) presented a large dataset for 18 fly transcription factors using tilingmicroarrays. He and his colleagues identified binding sitesfor multiple factors...
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