Báo cáo y học: " Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycin" pot
Báo cáo y học: " Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycin" pot
... greatpower. In particular, we examined whether the biochemistryunderpinning the developmentally arrested, infective J2 stage of H. glycines is functionally analogous to that of the dauer stage in C. elegans. ... R211Research Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycinesAxel A Elling*†‡, Makedonka Mitreva§, Justin Recknor¶, ... could ask whether the dauer expression profiles of C. elegans and Caenorhabditis briggsae are the same orwhether the expression profiles of H. glycines infective J2 and M. incognita infective J2...
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Báo cáo y học: "Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules" ppt
... sentinel system against patho-gens. The pathogenic significance of aberrant production of inflammatory cytokines and chemokines in the lunghas been given increasing attention and a variety of cytokines ... tothat in HTLV-I-infected T cells. The results of the presentstudy suggest that lung production of inflammatorycytokines and chemokines by HTLV-I-infected epithelialcells, in addition to that by ... staining for Tax protein in the cytoplasm of epithelial cells (A and D), and infiltrated lymphocytes (B and E) and macrophages (C and F).Retrovirology 2008, 5:86 http://www.retrovirology.com/content/5/1/86Page...
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Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... dysfunction may beimproving or worsening in the face of no or minor changes in APACHE score. Inherent in such delays in escalating therapymay be the impression held by some that apparent clinical ... significant amount of time in order to determine a 'clear' increased or increasing risk of death.On the other hand, because many clinicians increasingly viewclinical stability in severe sepsis ... remainsunacceptably high at 20 to 35% and because the incidence of severe sepsis is steadily increasing, the total number of deathscontinues to increase [1-3]. In the setting of severe sepsis, early multi-modal,...
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Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... of the transport of polyamines in and out of the cell also participates in keeping the polyamine pools a t an a ppropriate level f or the ongoingcellular activities. The function of the polyamines ... comparingdifferent cell lines [9,12,14]. In the polyamine m etabolicpathway, the induction of SSAT results in the acetylation of spermine and spermidine, which are subsequently oxidizedby polyamine ... theyhave a r ole in apoptosis [2–5] as w ell. The biosynthesis and catabolism of the polyamin es are tightly regulated, whichimplicates the i mportance of a balance of polyamine levels in the...
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Báo cáo y học: "p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis" ppsx
... of cDNA subclones with mutations was higher in the FLS than in matched synovium. This is most probablybecause the cells bearing mutations in the intact tissue(synoviocytes in the intimal lining) ... present in the rheumatoid synovial intimallining and that these regions produce significantly higheramounts of IL-6 [9]. However, the relationship betweenmutations and the synovial invasion ... has not been systemat-ically examined. In the present study, we first examined paired samples of synoviocytes isolated from the erosive front of synovium and from regions not directly adherent...
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Báo cáo y học: "Successful desensitization with human insulin in a patient with an insulin allergy and hypersensitivity to protamine: a case report" pptx
... treatment of allergies due to insulin prepara-tions has been reported during the last few years. In cases of hypersensitivity against protamine, the replacement of protamine-containing insulins by insulins ... adminis-tration of human insulin. After 3 days of therapy, ourpatient tolerated the formerly incompatible glargine insu-lin and showed only minimal local reactions at the injec-tion site and ... with insulin. The administration of different insu-lins (i.e. insulin detemir, insulin glargine, and humaninsulin) resulted in the development of pruritic plaqueswith a diameter of >15...
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Báo cáo y học: "Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembl" potx
... interaction.To further uncouple the phenotype induced by S40Fmutation from the underlying L-domain function of the ALIX binding site, we investigated whether ALIX canrescue the infectivity of t he S40F ... involved in the endocytotic recycling of cell surface receptors and in cytokinesis [4,7-17]. The L-domain activity of p6 is mainly driven by the 7PTAP10motif that is responsib le for the recruitment ... induced bymutations in the ALIX bind ing site are depending on the type of amino acid that is mutated [36]. Mutation of the 35LYP37sequences in the ALIX binding site reducesrelease and in fectivity...
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Báo cáo y học: "Recently published papers: Novel therapies in chronic obstructive pulmonary disease, cardiac chemicals and intensive care outcomes" ppt
... outcomes.Alberda and colleagues [12] published a multicentreobservational study examining the relationship between the amount of energy and protein administered during ICU stay and clinical outcomes in critically ... Confidential Enquiry into Patient Outcome and Death: Adding Insult to Injury - a Review of the Care of Patients Who Died in Hospital with a Primary Diagnosis of Acute Kidney Injury (Acute Renal Failure) ... outcomesBurtin and colleagues [10] investigated whether a dailyexercise session, using a bedside cycle ergometer, is a safe and effective intervention in preventing or attenuating the decrease in functional...
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Báo cáo y học: "PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunctio" ppsx
... partly by inhibiting lymphocyte apopto sis and reversing monocyte dysfunction by modul ating cytokineproduction. Anti-PD-L1 antibody administration may bea promising therapeutic strategy for ... equally to this article. Theyparticipated in the study design, coordinated the CLP surgery and detectedall the samples by flow cytometry, TUNEL and ELISA kits. They also helpedto analyze the ... partly by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction. Anti-PD-L1 antibody administration may be a promising therapeutic strategyfor sepsis-induced immunosuppression.IntroductionSepsis,...
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Báo cáo y học: "Are parental concerns for child TV viewing associated with child TV viewing and the home sedentary environment" pps
... viewing (mins/day) and maternal edu-cation, and accounted for potential clustering by school(unit of recruitment) using the ‘cluster’ command.ResultsCharacteristics of the 1128 children in the ... 1).Parents of older children reported watching TV, videosor DVD’s together with their child, and eating dinner in front of the TV together with their child more often thanparents of younger children. ... study include the large sample of chil-dren which allowed stratification by age group, the socioe-conomic diversity of the sample, and the comprehensiveexamination of the home sedentary environment....
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