Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc
Báo cáo y học: "Differential cellular FGF-2 upregulation in the rat facial nucleus following axotomy, functional electrical stimulation and corticosterone: a possible therapeutic target to Bell’s pals" doc
... demonstrated increased synth-eses of the cytoskeletal proteins actin and tubulin afteraxotomy of the rat facial nerve simultaneously to the enhanced NF contents and a low regulation of NFsynthesis. ... the intensity of the FGF-2 immunoreactivity increased slightly in the cytoplasm of neuronal profiles seven days after the axotomy as evaluated qualitatively by means of a directmicroscopic analysis ... further analysis of the immunostaining speci-ficity, sections were also incubated with the solvent of the primary or secondary an tibody solutions as well as the solvent of the avidin-biotin...
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Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc
... the binding of ligands with primordial proteins would also be a critical step in the origin of life. Thus, it is intriguing to explore the chro-nology of ligand -protein binding and answer the ... significant implications for tracing the important events in the origin of life and as well as for understanding the new paradigms in drug discovery.ResultsDistribution patterns of ligands in the protein ... of ligand -protein bindingFigure 1Power-law behaviors of ligand -protein binding. The number of ligands (N) decays with an increase in the number (L) of (a) domains and (b) folds that bind the...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... revealed the predominance of two amino acids: alanine (39.2%) and glycine (30%). Interestingly, the proportions are very similarto those found in WSM for alanine and glycine.Curiously, the presence ... Hydroxyproline, hydroxy-lysine and phosphoserine were not detected in WSM, WIM,EDTA-SM and EDTA-IM. The comparison of the amino acid composition of the main peak obtained from AE-HPLC of WSM and ... Proline, hydroxyproline and hydroxylysine were examined at 254 nm by reverse-phaseHPLC of their phenylisothiocarbamate derivatives [26], asreported previously [20]. The serine, threonine and tyrosinecontents...
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Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx
... of a variety of inflammatory chemokines and their receptors [5,6]. In vitrostudies have suggested that both so-called homeostaticchemokines and inflammatory chemokines, including CCchemokine ... within the inflammatoryinfiltrates in the joints of the CCR2–/–mice [19].Data from the knockout mice suggest that at least someindividual inflammatory chemokine receptors are pivotal in the ... shown to inhibit 90% of the monocytechemotactic activity present in the synovial fluid of the majority of RA patients [30]. In a randomized studypatients with active RA were treated for 2 weeks...
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Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... processesunderlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered therapy for PAHincreases the importance ... at1 year and 2 years of 96% and 89% compared withViewpointCold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertensionFrances C HallUniversity of ... cell dysfunction is characterised bydecreased production of the vasodilators nitric oxide and prostacyclin, and by enhanced release of endothelin-1.Endothelial cell dysfunction influences the...
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Báo cáo y học: "Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection" docx
... acclimated to the treadmill bygradually increasing the running speed and time as follows:day 1, 10 minutes at 10 m/min; day 2, 15 minutes at 12 m/min;day 3, 20 minutes at 15 m/min; day 4, 30 minutes ... at 18 m/min; and day 5, 35 minutes at 20 m/min. On day 8 and thereafter, the rats were forced to run for 55 minutes a day at 20 m/min,with the first 10 minutes consisting of a 12 m/min warm-up.Rats ... sulfate increased sharply 1 day after injection of chymopa-pain into the knee joint in rabbits [26]. The serum keratansulfate also sharply decreased, and these changes wereaccompanied by depletion...
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Báo cáo y học: "Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity" pdf
... correlationbetween MMP activity (evidenced by the 342FFGVG-G2 and CTX biochemical markers) and the inability of cytokine-treatedchondrocytes to initiate and/ or maintain anabolic activity.Switching to anabolic ... generated by an array of MMPs, of which MMP-2 and MMP-9 are only a subset. Onother occasions, the presence of these gelatinases has beena valid indication of total MMP activity and thereby the cata-bolic ... synthesis in cartilage explants was measured by the concentration of N-terminal pro-peptides of type II collagen in the condi-tioned medium using the PIINP enzyme-linked immunosorbent assay...
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Báo cáo y học: "AIT test has no problem in the detection of anti-ribosomal P" ppsx
... qualitycontrol program run by the Korean Society of LaboratoryMedicine [3]. In 1999 and 2007, reports of antinuclearantibody test using the IT-1 cell line on 208 and 588systemic lupus erythematosus ... commercialized and passed inspection by the Korea Food and Drug Administration in South Korea.Currently, IT-1 is being used under the name of the autoimmune target (AIT) test and it participates in the ... anti-ribosomal P (anti-Rib-P) in the pictures they revealed. In addition to the anti-Rib-P that Mahler and colleagues mentioned, limitations of the HEp-2 cell line in the detection of autoantibodies such...
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Báo cáo y học: " AIT test has no problem in the detection of anti-ribosomal P – authors’ response" docx
... systematic study is mandatory to compare the sensitivity and specificity of the AIT test for the detection of anti-Rib-Pantibodies and other antibody specificities using a variety of contemporary diagnostic ... assay, and then used these sera to determine the positivity and staining patterns in the AIT test. This method raises concernsbecause it is generally known that immunodiffusion is arelatively insensitive ... Despite the clearance of the AIT test by the South Korea Food and Drug Administration, to the best of our knowledge this test is not widely used as ascreening method – neither is it approved by the...
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Báo cáo y học: " Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity" potx
... in the thyroid glands. The ability of cancerous thyroid cells toactively transport iodide via NIS has provided a unique and effective delivery system for the detection and destruc-tion of these ... functionally expressed in thyroids, salivaryglands, gastric mucosa, and lactating mammary glands [1].NIS mediates the active transport of iodide into the folli-cular thyroid cells and, in turn, ... Moreover, His-226 is critical for the iodide uptake activity of NIS [13]. Furthermore,arginine residues of organic anion transporter 1 influ-ence the binding of glutarate and interact with chloride[28]....
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbáo cáo khoa học y họcBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)