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Báo cáo y học: "Regulatory conservation of protein coding and microRNA genes in vertebrates: lessons from the opossum genome" pptx

Báo cáo y học:

Báo cáo y học: "Regulatory conservation of protein coding and microRNA genes in vertebrates: lessons from the opossum genome" pptx

... are found in the introns of coding genes and therefore are probably regulated by the promoters of the genes in which they reside [26], others are located in the intergenic parts of the genome. ... TSS in varioustypes of protein coding genes in a way similar to ourobservations.ConclusionThis study is the first to analyze conservation of the upstreamregions of protein coding genes in ... regions of protein coding and intergenic miRNA genes Conservation of the 5 kilobases (kb) upstream regions of allRefSeq protein coding genes as well as the known intergenicmiRNA genes was...
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Báo cáo y học: "Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages" pot

... solelyinvolved in the ligand binding affinity [26]. Interestingly, the modular decomposition of the Gαs subunit (1azs, chain C)shows that the adenylyl cyclase-binding site is divided intotwo ... conformationalchanges in the active site and increases its hydrophobicity,resulting in increased binding affinity to the other androsten-edion (Andro1) [32]. The modular decomposition of this pro-tein indicates ... analyze the distribution of protein modules intodomains and to calculate the distribution of the long-rangeinteractions at the inter-modular interfaces and in the intra-modular regions. Using...
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Báo cáo y học: "Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspect" potx

... non-synonymous site to the number of synonymous SNPs per synonymous site. The numbers of syn-onymous sites and non-synonymous sites were calculatedusing the method of Miyata and Yasunaga [74]. The ... arising from the popularity of genes in sequencing efforts, which could bea problem when using SNP density; and it is normalized by the number of synonymous and non-synonymous sites, so the numbers ... [43], and that they are more likely to beinvolved in regulatory functions and protein- protein interac-tions [44,45]. We obtained disorder predictions usingDISOPRED2 [43] and retained only the...
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Báo cáo y học: "A Comparison of Immuncapture Agglutination and ELISA Methods in Serological Diagnosis of Brucellosis"

... re-spectively. Evaluation of two Ig’s together rather than one by one increases their sensitivity and specificity values. The Ig G and Ig M sensitivities found in our study were higher in comparison ... titers and the advantage of identifying different clas-ses of antibodies in comparison to other agglutination methods. Different results may be obtained depend-ing on the nature of anti-globulin. ... presump-tive diagnosis of brucellosis which were sent to Cen-tral Microbiology Laboratory of Selcuk University Meram Faculty of Medicine from various clinics were included in the study and kept at -70ºC...
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Báo cáo y học: "Comparative study of serum Na+ and K+ levels in senile cataract patients and normal individuals"

... University, Oklahoma, in 1976, MSc (Biochemistry) from University of Oklahoma in 1978, and PhD (Nutritional Biochemistry) from University of Arizona in 1981. He is currently an associate professor in ... of Biochemistry and Nutrition in Iran University of Medical Sciences. He is interested in study of nutrition and trace elements in human blood. Manuchehr Imamian obtained BSc in Chemistry from ... bbiiooggrraapphh y y Mansour Mirsamadi obtained MD degree from University of Tehran in 1978, and then studied ophthalmology for three years in Iran University of Medical Sciences. He is currently an...
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Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

... that the presence of the metalcofactor helps maintain the integrity and stability of enzyme–substrate complex. It is therefore likely that the ion simultaneously interacts with both the enzyme and UDP-Glc ... toxin in either gluco-syltransferase or glucosylhydrolase reactions. Using a com-petition assay, the affinity of UDP-Glc was determined to be45±10 lM in the absence of Mg2+. The binding of ... activityresides in an N-terminal domain of  660 amino acids [14]. The C-terminal domain, on the other hand, is responsiblefor interacting with a carbohydrate receptor on the surface of intestinal endothelial...
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Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx

... high and constant level of c-Myc. Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc byphosphorylation of the serine 62 residue in the N-terminal of c-Myc [24]. They ... hypothesizedthat c-Myc plays a central role in TGF1 signaling for cellgrowth stimulation. Additionally, to examine the possibility of involvement of the MAPK pathway in regulation of c-Myc sta-bility, we ... a yeast two-hybrid system. In order to bind DNA,c-Myc must dimerize with Max. 10058-F4 inhibits c-Myc tran-scriptional activity by disrupting the c-Myc/Max association. The half-life of Myc...
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Báo cáo y học:

Báo cáo y học: "Indigenous utilization of termite mounds and their sustainability in a rice growing village of the central plain of Laos" pdf

... due to the years of habitation, population size, termite species, the degree of weathering and the extent of use by villa-gers. Further study is required. The volume of 53 mounds, including mounds ... termite mounds in paddy fields aredeclining and may disappear in the future. However, the villagers’ use of mounds in areas far from the village set-tlementmaynotdifferfromthatinthestudiedarea.Moreover, ... article as: Miyagawa et al.: Indigenous utilization of termitemounds and their sustainability in a rice growing village of the centralplain of Laos. Journal of Ethnobiology and Ethnomedicine 2011...
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Báo cáo y học:

Báo cáo y học: " Suspected association of ventricular arrhythmia with air pollution in a motorbike rider: a case report" pptx

... noted in patients with false tendons, ischaemic orinflamed myocardium and during infection, hypoxia,anaesthesia or surgery. They can be provoked by a variety of medications, by electrolyte imbalance, ... would have been of interest to obtainan ambulatory ECG during a motorbike ride in order toreport changes in autonomic factors or changes in cardiacelectrical instability in the myocardial substrate ... patientfor publication of this case report and any accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of this journal.Acknowledgements The author would...
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