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Báo cáo y học: "Novel rapid infusion device for patients in emergency situations" pptx

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Báo cáo y học: "Garden of therapeutic delights: new targets in rheumatic diseases" pptx

... block intracellular enzymes thatcontrol signaling pathways. Inhibitors of tyrosine kinases expressed in lymphocytes, such as spleen tyrosine kinase and Janus kinase,are being tested in autoimmune ... few key cytokine targets are discussed.ReviewGarden of therapeutic delights: new targets in rheumatic diseasesJean M Waldburger and Gary S FiresteinDivision of Rheumatology, Allergy and Immunology, ... Class I PI3Ks are a family of intracellular signaling proteins involved in many aspects of cell biology, including adaptive and innate immunity [65].They are composed of heterodimers assembled...
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Báo cáo y học: "Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet" pptx

... insulinresistance, induction of SLPI locally in adipose may alsoplay a role in the prevention of inflammation-inducedinsulin resistance. In summary, we have demonstratedthat obesity is accompanied by increased ... anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet. Journal of Inflammation 2011 8:5.Submit your next manuscript to BioMed Central and take full advantage of: ... mechanism by which SLPI counteracts inflam-mation in adipocytes.DiscussionInflammation plays a major role in obesity-induced insu-lin resistance by the release of multiple inflammatorycytokines...
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Báo cáo y học: " Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet" docx

... activated in adipose tissue in obesity [12,13], theinduction of SLPI in adipose tissue during obesity may beinfluenced by the activation state of the TLRs. Higherexpression of SLPI in the visceral ... Adapala et al.: Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet. Journal of Inflammation 2011 8:5.Submit your next manuscript to BioMed Central and take full ... adipocytes and whole adi-pose tissue (Figures 2A, B and 2C). Regulation of SLPI expression in adipocytes by inflammatory stimuli and anti-inflammatory effect of SLPI Adipocytes express both TLR2 and...
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Báo cáo y học: "Benzodiazepine Use and Misuse Among Patients in a Methadone Program" potx

... as an anxiety cop-ing strategy [2]. In addition, it has been shown thatindividuals who abuse BZD are at increased risk of con-tinuing opiate abuse [3 ]and failing to stay in methadone treatment ... the methadone program? Did your BZD use increase or start after com-ing to the methadone program? How many days didyou use any BZD in the past 30 days? (The actual Ques-tionnaire is available ... eroin addicts both before entering and during their methadone treatment.This study is among the few in the U.S. [23] that clo-sely examin es BZD use a nd misuse among methadon e-maintained patients...
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Báo cáo y học: "Open Access Collaborative care for patients with bipolar disorder: a randomised controlled trial" doc

... guidelines;and enhancing access to care and continuity of care. The care manager, a nurse or a social worker, provided activelyoutreaching care when a patient was at risk of losing con-tact with mental ... measures are psychosocial function-ing, symptoms, and quality of life. Secondary outcomemeasures are mastery, attitude towards medication andsatisfaction with care. Family members or friends of patients ... Renes4, Aartjan TF Beekman5andRalph W Kupka6AbstractBackground: Bipolar disorder is a severe mental illness with serious consequences for daily living of patients andtheir caregivers. Care as...
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Báo cáo y học: "Dysregulated apoptosis and NFκB expression in COPD subjects" pptx

... (COPD) is charac-terised by an inflammatory infiltrate consisting mainly ofneutrophils [1], with increased neutrophils and inflam-matory mediators in both bronchial tissue and airways of COPD ... recruitment in the airways and inhibition of apoptosis [33,34].Our findings show that the percentage of neutrophils in early stage apoptosis are significantly reduced in COPD subjects and in healthy smokers ... IL-6, IL-8 and GM-CSF are importantcytokines in the regulation of airway inflammation and several studies have shown these cytokines play a key role in the pathophysiology of COPD [37]. In vitro...
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Báo cáo y học: " Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis" ppsx

... primer for TXNDC5, 5’ -GCCTCCACTGTGCTCACTGA-3’;forwardprimerforhumanb-actin, 5’-TGGCACCCAGCACAATGAA-3’;andreverseprimer for human b-actin, 5’-CTAAGTCATAGTCCGCC-TAGAAGCA-3’. Primer efficiency was ... ofgenotyping.Statistical analysisGenotyping SNPs were analyzed for association by com-parison of the MAF in cases and controls. Associations ofSNPs w ith RA and AS were eva luated using odds ratiosTable ... wasmeasured using a plate reader (Synergy HT, Bio-Tek,Winooski, VT, USA). We repeated the ELISA three timesand obtained the similar results.Sandwich ELISA has low inter-assay and intra-assayvariability...
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Báo cáo y học: "The epidemiology of low back pain in primary care" pptx

... and Back Pain Survey - The prevalence of low back pain andrelated disability in Saskatchewan adults. Spine 1998,23(17):1860-1867.5. Volinn E: The epidemiology of low back pain in the rest of theworld. ... Clinicalguidelines for the management of low back pain in primary care. Spine 2001, 26(22):2504-2514.37. Cherkin DC, Deyo RA, Wheeler K, Ciol MA, Carey T: Physicianviews about treating low back ... J: The natural history of idiopathic low back pain - A three-year follow-up study of spinal motion, pain and functional capacity. Scandinavian Journal of Rehabilitation Medicine 1985, 17:1-4.53....
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Báo cáo y học: "Characteristics and outcomes of cancer patients in European ICUs" pps

... predominance of respiratory infections, asreported previously [17,34,35]. Apart from a higher incidence of E. coli and abdominal infections in patients with solidtumours than in non -cancer patients ... insufficiency in patients with solid tumours, and more patients with AIDS in patients with haematological can-cer. Corticosteroids and chemotherapy were more commonlyused in patients with cancer than in ... therapeutic and prognosticfactors of ICU patients in European countries, and wasendorsed by the European Society of Intensive Care Medicine.Although this observational study did not require any deviationfrom...
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Báo cáo y học: "Bench-to-bedside review: Mobilizing patients in the intensive care unit – from pathophysiology to clinical trials" pot

... loss in the critically ill patient. Importantly,ReviewBench -to- bedside review: Mobilizing patients in the intensive care unit from pathophysiology to clinical trialsAlex D Truong1, Eddy Fan1, ... anti-inflam-matory cytokines during moderate exercise may play animportant role in muscle preservation and protection.Physical therapy in the intensive care unit Physical therapy practices vary greatly ... improving rehabilitation in the ICU. Indeed, the need for early activity in critically ill patients was recently reinforced by European guidelines forphysiotherapy in the ICU [68].A multidisciplinary...
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Báo cáo y học: " Antimicrobial breakpoint estimation accounting for variability in pharmacokinetics" pps

... estima-tion of breakpoints has become a necessary step in mod-ern microbiology laboratory practice. Breakpoints areestimated in a variety of ways, the most widely used beingthe minimal inhibitory concentration ... for breakpoint assessment, MIC does not include drug dispo-sition or other potential variability information. In fact,MIC is measured under almost deterministic conditionssince variability ... certain site in the body (a target organ for exam-ple), it behaves in a similar way as in vitro. In the follow-ing, we will include this efficacy function E in ourapproach to predicting the...
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Báo cáo y học: " Empiric anti-Candida therapy for patients with sepsis in the ICU: how little is too little" docx

... help refine the best empiric anti-Candida strategy for ICU patients with sepsis. Competing interestsYG has received research funding and is on the advisoryboard for Merck and Pfizer. YG is also ... age-matchedrepresentatives of the general population [12,13]. These over-estimations exaggerate the affordability of empiric micafungin.Nevertheless, the main finding of this study by Zilberberg andcolleagues is encouraging. ... mortality ofnosocomial candidemia, revisited. Clin Infect Dis 2003, 37:1172-1177.6. Kumar A; CATSS Study Group: The high mortality of Candidaseptic shock is explained by excessive delays in initiation...
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Báo cáo y học: " Binary gene induction and protein expression in individual cells" pptx

... observe binary, hybrid and graded protein expression. Protein expression histograms of β-gal, Luc and GFP In examining different mode of gene induction, severalreporter genes have been used. To investigate ... of gene expression histograms for binary and graded modes of gene inductionFigure 1Schematic representation of gene expression histograms for binary and graded modes of gene induction. Gene Expression ... replaced with binary ones if β-gal is used as thereporter protein. In addition to the binary and graded pro-tein expression patterns, the gene induction model alsocaptured an array of intermediate...
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Báo cáo y học: "Novel rapid infusion device for patients in emergency situations" pptx

... airembolism or hemolysis. We u sed Intrafixđsafeset (M/SB. Braun Melsungen, Germany) IV infusion assemb ly for infusing fluids instead of conventional IV tubing assem-bly, as this IV infusion set ... catheters inserted in major veins[6,7] and manual injection of fluid [8], to obtain desiredresult.Presently, rapid infusion systems (Haemonetics Corp.,Braintree, MA) are commonly used to administer ... switching of the bottle with air in the infusion system. Thus further reduces the time of admin-istration as compared to the conventional IV tubing, thusideal for rapid infusion of fluids in emergency...
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Báo cáo y học: "Undisclosed cocaine use and chest pain in emergency departments of Spain" pdf

... consumption in 6.4% (95% confidence interval: 2.0%–10.4%) of adultpatients presenting at Emergency Department for chest pain. This finding in chest pain patients who consented tourine analysis suggests ... attentionDiscussion In USA, with similar cocaine consumption rates to Spain,the Drug Abuse Warning Network DAWN estimates that cocaine was involved in 10% of drug misuse/abuse EDvisits [8,9]. In the study of ... chest pain patients is around 30% [6,7,10].As in other studies, the great majority of our cocaine- con-suming patients with chest pain were young people, in their third decade of life, and in...
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