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Báo cáo y học: " A new miniaturized system for extracorporeal membrane oxygenation in adult respiratory failure" potx

Báo cáo y học:

Báo cáo y học: " A new miniaturized system for extracorporeal membrane oxygenation in adult respiratory failure" potx

... of a new miniaturized system for extracorporeal membrane oxygenation in a large adult study population with severe ARDS. CrucialTable 5Laboratory variables before, during and after extracorporeal ... possible in patients with a risk of bleeding andolder age, which had been traditionally contraindications for ECMO therapy. A fast and sustained rise in PaO2/FiO2 as wellas a rapid decrease in ... Thiagarajan RR, Rycus PT, Bartlett RH, Bratton SL: Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multi-center database. Intensive CareMed 2009, 35: 21. Kolla...
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Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx

Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx

... mechan-ism, although a Boltzman analysis suggests a very smallpopulation in anything other than the vibrational groundstate. An alternative explanation might be found in invoking a more ÔrelaxedÕ ... thisunderstanding is gained, H-tunneling can then be used as a tool for (a) increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling ofdynamics to the reaction ... recently in reactions catalysed by lipoxygenaseand mutants thereof [40]. We have attempted to gain anearly insight into the effects of compromising mutations oncatalysis by studying C–H and C–D...
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Báo cáo y học: " A remission spectroscopy system for in vivo monitoring of hemoglobin oxygen saturation in murine hepatic sinusoids, in early systemic inflammation" doc

... reduction in hepatic sinusoidalHbsO2 during the early stages of systemic inflammation. In parallel, we detected an increasing NAD(P)Hautofluorescence representing an intracellular inadequateoxygen ... normal saline was adminis-tered at a rate of 0.4 ml/hr to maintain normal mean arte-rial pressure. As formerly described [4], and for therealization of the intravital microscopy procedure in anaesthetized ... significant decrease in hepatic sinusoidal HbsO2. In parallel, we detected an increasing NAD(P)H autofluorescencerepresenting an intracellular inadequate oxygen supply. Both changes are accompanied...
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Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc

... determine the magnitude of any underly-ing risk of cancer that may already be present in patients withRA compared with the general population.Data from several studies, reviewed by Chakravarty and ... population may be characterized byCI = confidence interval; COX-2 = cyclooxygenase-2; DMARD = disease-modifying antirheumatic drug; NSAID = nonsteroidal anti-inflammatory drug; RA = rheumatoid arthritis; ... severity of disease as well as RAtreatment. In relation to treatment effects, nearly all patients in these studies have received treatment for their RA, and it isbecoming increasingly likely that...
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Báo cáo y học: " A self-rating scale for patient-perceived side effects of inhaled corticosteroids" potx

... thedata, performed the statistical analysis and drafted themanuscript. EVS AJL and RS participated in the studydesign, supervised statistical analysis and assisted in theinterpretation of statistical ... throat• an unpleasant feeling in your throat Oropharyngeal Itching – 2 items:• a dry throat • an itchy feeling on the roof of your mouth• an itchy feeling in the back of your throatOropharynx ... H, Tang Y, FalcozC, Daley-Yates PT, Krieg M, Stockmann R, Barth J, Lawlor C, Moll-mann AC, Derendorf H, Hochhaus G: Single-dose and steady-state pharmacokinetic and pharmacodynamic evaluation...
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Báo cáo y học: "A Protein Similarity Approach For Detecting Prophage Regions In Bacterial Genomes" potx

... technically difficulty relies in defining prophage sequences in bacterial genomes as mostly they are cryptic or in the state of mutational decay. Prophages account for a substantial amount of interstrain ... prophage elements in a representative set of bacterial genomes using a protein similarity approach. It has been observed that lambdoid phages have a strong tendency to get integrated near a dehydrogenase ... Biology 2005, 6:P11Deposited research article A Protein Similarity Approach For Detecting Prophage Regions In Bacterial Genomes Geeta V Rao, Preeti Mehta, Srividhya KV and Krishnaswamy S1§Address:...
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Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx

Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx

... neutro-phils, macrophages and lymphocytes increase in number atsites of in ammation and each are capable of modifying theoverall in ammatory response [23]. Eosinophils, are ofparticular interest in asthma ... with individual tyrosine kinases in a cell-free format.Tyrosinephosphorylation of GST–cyto-wt and GST–cytoY !F mutants with a mix of Lck, Jak3, Emt and ZAP-70 tyrosine kinases (starting at a concentration ... (data not shown).Cytoplasmic signalingKinase assay results. The kinase assays indicate that thecytoplasmic domain of the siglec protein can be phos-phorylated by representatives of at least...
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Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

... phosphorylation of tyrosine Y5 81 creating a more favourable conformation of thesequence surrounding the tyrosines Y5 79 and Y5 81, therebyincreasing binding affinity. Interestingly, the EpoR contains a ... providing an additional contact withthe SH2 domain of SOCS-3 involving R94. A conforma-tional change induced by the phosphorylation of tyrosine Y4 31 may also contribute to the increase in binding affinitycompared ... domain that inhibits JAK kinases. Nature 387,921–924.7. Naka,T.,Narazaki,M.,Hirata,M.,Matsumoto,T.,Minamoto,S., Aono, A. , Nishimoto, N., Kajita, T., Taga, T., Yoshizaki, K.,Akira, S. &...
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Báo cáo y học: : A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis

Báo cáo y học: : A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis" pptx

... (boldface): S1 for ARAA and ERAA, S2 for KRAA, S3 for RRAA (divided into S3P for QRRAA and S3D for DRRAA according to position 70), and X for all non-RAA motifs. The conventional classification ... prognosis of early RA. Citrulline is a nonstandard aminoacid, generated by post-translational modifications of severalproteins by deimination of arginine residues by peptidy-larginine deiminases [3,4]. ... for lysine, R for arginine (basic amino acids (polar and positively charged)); group 3 = E for glutamic acid, Q for glutamine (the amide corresponding to E), D for aspartic acid, and N for asparagine...
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Báo cáo y học: "A new approach to understanding the impact of circadian disruption on human health'''' pps

... here are onlythe Daysimeter data.Measuring and characterizing circadian behavioral entrainment patterns in nocturnal rodentsData collectionForty albino female Sprague-Dawley rats (Rattus ... rats instantly travelledback and forth from Asia to the Americas every other day).Animals were housed individually and allowed to eat anddrink ad libidum.Wheel running was measured continuously ... associatedwith circadian disruption in humans can be parametri-cally studied using animal models.MethodsMeasuring and characterizing circadian entrainment patterns actually experienced by humansDaysimeterThe...
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