Báo cáo y học: "Weakness in the ICU: a call to action" potx
Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... 7(2):94-100 â Ivyspring International Publisher. All rights reserved Research Paper Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic ... IP, et al. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus. Clin Pharmacol Ther. 2003; 74: 245-54. ... affect pharmacokinetics are the drug transporters and the metabolizing en-zymes [7,9]. CYP3A, the primary subfamily of the cytoch-rome P450 (CYP) enzymatic system, is responsible for the metabolism...
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Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... estimate the extent of the acidic regionresponsible for cytochrome c docking. While no directstructural information is at hand for the docked complex, the interaction domain for cytochrome c on the ... denitrificans; cytochrome c oxidase; docking site; electron transfer; biphasic kinetics. Cytochrome c oxidase is the terminal complex of the respiratory chains of mitochondria and many bacteria[1–4]. ... kinetics may not be solely dueto changes in the initial ferrocytochrome c concentration, and rather are an intrinsic enzymic property ensuing from the mechanistic details of the cytochrome oxidase...
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Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... raises the possibility that any one or acombination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity to fractionate lipid emulsions into relatively ... apolipoprotein E3 and E4 to emulsions (Eur. J. Biochem. 269) 5941 Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions Matthew A. Perugini1, Peter ... ApoE3 and ApoE4 with EggPtdCho /TO lipid emulsions The binding of apoE3 and apoE4 to lipid particles wasalso assessed using size-fractionated emulsions comprised of egg yolk phosphatidylcholine...
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Báo cáo y học: Advances in the Surgical Management of Chronic Rhinosinusitis" pot
... technology has been,theoretically, to increase the safety and com-pleteness of surgery in addition to increasing the confidence of the surgeon. This accounts for the increasing numbers of health ... state of the art in endoscopic sinussurgery includes many recent innovations. Prob-ably the most fundamental change in sinus surgeryhas been the adaptation of rigid endoscopes for use in the ... sur-gical intervention would include the presence of anatomic abnormalities that could predispose the Rhinitis and Sinusitis Advances in the Surgical Management of Chronic RhinosinusitisErin D....
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Báo cáo y học: "Alterations in the complement cascade in post-traumatic stress disorder" potx
... modulating the immune function [42,43]might affect the initial steps in the inflammatory cascade and thus influence alterations in the functional activityof the major mediator of the inflammatory ... protein C3 is the initial point of the alternativepathway,and,atthesametime,aconvergepointofallthree complement activation pathways, i.e. starting pointfor the terminal pathway [16-18].Hypoactivation ... levels of the anti-inflammatory cytokine IL-4 [12].This study was focused on the functional state of the major mediator of the inflammation, the complement system, in PTSD. The results obtained clearly...
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Báo cáo y học: "Developments in the clinical understanding of osteoarthritis" docx
... the synovium, in ligaments especially near their insertions, in bone, in muscle, and in the outer third of the meniscus in the knee. In an unusual study in which the lead investigator became the study subject ... providednew insights into how OA may be successfully managed. The symptoms of osteoarthritis: pain andinstability The pain of OA is activity-related, with pain coming ongenerally only when a person ... not the only symptom of OA experienced by patientswith knee and hip OA. They also frequently experience asensation of instability or buckling. The most commonsymptom is one of shifting or instability...
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Báo cáo y học: "Developments in the clinical understanding of rheumatoid arthritis" ppt
... consequence of the activation of many cell populationsand, ultimately, of the upregulation of proinflammatory cyto-kines [19,20]. By whichever means they themselves becomeactivated, they induce ... activity. The degree of disease activityat the start of a disease-modifying therapy is amajor determinant of the disease activityattainable in treatment.Background and evidence The pivotal clinical ... regardless of their level of improvement.These and other insights mandate a change in clinical trialreporting by requesting the provision of information on cate-gories of disease activity attained in...
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Báo cáo y học: "Developments in the scientific and clinical understanding of the spondyloarthritides" pptx
... the definition of the BathAnkylosing Spondylitis Disease Activity Index (BASDAI) [21], the Bath Ankylosing Spondylitis Functional Index (BASFI), and the Bath Ankylosing Spondylitis Metrology ... and scientific understanding of the spondyloarthritides(SpA), which can be separated in predominantly axial and predominantly peripheral SpA. The clinical progress includes the development of ... manifes-ReviewDevelopments in the scientific and clinical understanding of the spondyloarthritidesJoachim SieperDepartment of Rheumatology, Campus Benjamin Franklin, Charité, Hindenburgdamm 30, 12200 Berlin, GermanyCorresponding...
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Báo cáo y học: "Developments in the scientific and clinical understanding of autoinflammatory disorders" doc
... proteins of apparently disparate function and cellular localisation. Pyrinis thought to interact with a variety of proteins within the cytoplasm and to play a key role in the modulation of inflammation ... characterised by fluctuating orirregularly recurring episodes of fever and systemic inflam-mation, affecting the skin, eyes, joints, and serosal surfaces.They include the hereditary syndromes familial ... homology with pyrin’s N-terminalsequence [12]. Members of the death domain superfamily areinvolved in the assembly and activation of apoptotic and inflammatory complexes through homotypic protein-proteininteractions...
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Báo cáo y học: "Agitation in the ICU: part one Anatomical and physiologic basis for the agitated state" ppt
... memory,working memory, memory indexing/storage, relatingexpectancy to reality, and internal inhibition. Memory isrecorded in several parts of the brain at same time as‘memory molecules’ for ... to the reticular activating system via the reticular formation, beginning in the medulla and extend-ing to the midbrain. This pathway links the brain withperception of external events. Pain ... noradrenergicneurons in these areas, increasing activity [63]. CRF mayReview Agitation in the ICU: part one Crippen R39 biochemistry, neurophysiology, and animal behavior.However, the lengthy ‘lag period’ before...
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Báo cáo y học: "Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity" ppt
... on x-ray crystallographic data, NMR and in vitro assembly models, the importance of major homol-ogy region [10], the binding site for cyclophilin A (CypA)[11,12], and the CA dimer interfaces ... proper CA cone formation and mutations in CA are lethal when they inhibit CA assembly by destabilizing the intra and/ or inter molecular CAcontacts, which ultimately abrogate viral replication. ... [13,14] are some of the functions in CA that have been characterised usingmutational analysis.Most of amino acid sequences in the CypA -binding loop of HIV-1 CA have been investigated using both...
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Báo cáo y học: "Incretins in the ICU: is insulin on its way out" pdf
... and induction of satiety[8-12]. The beauty of GLP-1 is that it does not stimulateCommentaryIncretins in the ICU: is insulin on its way out?Michelle A Kovalaske and Gunjan Y GandhiDivision ... effects on insulin and glucagon in hospitalized patients. Finally, GLP-1 in and ofitself may not cause hypoglycemia. When used in conjunctionwith insulin, however, effects on hypoglycemia will ... citation purposes) insulin secretion in euglycemic ranges, thus potentiallyeliminating the risk of hypoglycemia – making GLP-1 a veryattractive pharmacologic option for treating hyperglycemia in hospitalized...
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Báo cáo y học: "Weakness in the ICU: a call to action" potx
... exercise capacityCommentaryWeakness in the ICU: a call to actionRobert D Stevens1, Nicholas Hart2, Bernard de Jonghe3and Tarek Sharshar41Departments of Anesthesiology and Critical Care ... indicate a paradigm shift to a proactive approach in managing neuromuscular complications in the ICU. In a recent issue of Critical Care, Gerovasili and colleagues[1] present results of a randomized ... ICUAW, a situation that has contributed to a sense of therapeuticnihilism among clinicians. New clinical trials are challengingthis perception. The management of ICUAW has traditionally emphasizedefforts...
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Báo cáo y học: "Anemia in the ICU: are your patients needin’ erythropoetin" doc
... as there is a demonstrated mortality benefi t, but these patients should be able to safely receive prophylactic heparin.Competing interests The authors declare that they have no competing interests.Published: ... however, are not entirely conclusive. With further analysis, the authors showed that the increase in throm botic events only aff ected patients not receiving heparin prophylaxis. e incidence ... Care Medicine 1999, 27: 2346-23502. Corwin HL, Gettinger A, Pearl GR, Fink MP, Levy MM, Shapiro MJ, Corwin MJ, Colton TC: E cacy of Recombinant Human Erythropoietin in Critically Ill Patients: ...
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Từ khóa: Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)