Báo cáo y học: "Thoracic epidural anesthesia in sepsis - is it harmful or protective" pps
Báo cáo y học: "Thoracic epidural anesthesia in sepsis - is it harmful or protective" pps
... output - measured in an additional group of animals, which were not investigatedwith intravital microscopy - remained constant in animals withinduced sepsis with and without epidural anesthesia. ... exhaled NO. This studyshows the importance of distinguishing between differentphases of disease, especially during early (hyperdynamic) andlate (hypodynamic) sepsis. One has to keep in mind that ... this, with some reporting decreased mortality in older animal studies [11] and newer meta-analyses [12,13] andothers reporting increased mortality in an animal model [14].The main problem with...
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Báo cáo y học: "Thoracic epidural anesthesia reverses sepsis-induced hepatic hyperperfusion and reduces leukocyte adhesion in septic rats" potx
... venolar temporary leu-kocyte adhesion in sepsis. Finally, intestinal injury and portal inflow of inflammatory medi-ators induce secondary hepatic inflammation [1,64,65]. Con-sequently, the decreased ... role in up-regulating IL-1beta andIL-10. Biochim Biophys Acta 2005, 1740:44 6-4 52.18. Yang S, Zhou M, Chaudry IH, Wang P: Norepinephrine-inducedhepatocellular dysfunction in early sepsis is mediated ... was not influenced in Sepsis + thoracic epidural anesthesia (TEA). Sinusoidal perfusion was neither influenced in Sepsis nor in Sepsis + TEA. Data (n = 8 in each group) are displayed as mean...
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Báo cáo y học: "Thoracic epidural anesthesia time-dependently modulates pulmonary endothelial dysfunction in septic rats" docx
... dependent in a peritonitismodel of sepsis. Intensive Care Med 2004, 30:182 1-1 828.20. Fischer LG, Hollmann MW, Horstman DJ, Rich GF: Cyclooxygen-ase inhibitors attenuate bradykinin-induced vasoconstriction in ... dysfunctiontypically seen in the presence of sepsis. Because the earlyphase of hyperdynamic circulation is typically followed by alate hypodynamic circulatory state in rats with sepsis second-ary to cecal ... 0.5%(15 μl/h -1 for 24 hours, SHAM + TEA). In the hyperdynamic sepsis group (6 hours after injury), normal saline (15 μl/h -1 )was continuously administered epidurally for 6 hours afterinduction...
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Báo cáo y học: "Deficient mitochondrial biogenesis in critical illness: cause, effect, or epiphenomeno" pps
... onincreasing and restoring wild-type mtDNA to restore cellularoxidative capacity and organ function in sepsis and shock.What is most exciting is that we are still gaining insight intothis ... [15,16]. At the organlevel, this down-regulated metabolic state may manifest as“organ dysfunction” or “organ failure”. During hypoxia,ischemia and in early or non-fatal sepsis, such a responseappears ... andmaintain viability by down-regulating oxygen consumption,energy requirements and ATP demand [15,16]. In the heartthis response is called myocardial hibernation and results in cardiomyocyte hypocontractility...
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Báo cáo y học: "Whole exome capture in solution with 3 Gbp of data" pps
... in efficiency are due to an increase in initial library com-plexity arising from better annealing efficiencies of theIllumina adapter. This is probably explained by the factthat Illumina adaptor sequences ... techniques withoutsacrificing reproducibility or specificity of either the cap-ture or variant discovery while maintaining all the advan-tages of solution-based techniques over microarraycapture.To ... cover-age distributions and reproducible variant discovery for avariety of genomic screening experiments. This work alsoshows the feasibility of using either SOLiD or Illumina-based sequencing...
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báo cáo khoa học: "Thoracic trident pigmentation in Drosophila melanogaster : Differentiation of geographical populations" ppsx
... check this hypothesis and also to analyse the physiological basis ofthis phenomenon.The latitudinal variation in trident intensity remains the main conclusion of thiswork. ... since all studied populations originated fromlow places. Many traits exhibit latitudinal clines in D. melanogaster such as mor-phology (DAVID et al., 1977), physiology ... on mating and territorialism in Drosophilamelanogaster. Behavior Genetics, 8, 48 7-5 02.JACOBS M.E., 1982. Beta-alanine and tanning polymorphisms. Comp. Biochem. Physiol.,72...
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Báo cáo y học: " Plantar calcaneal spurs in older people: longitudinal traction or vertical compression" ppsx
... enthesis, which may have impli-cations for the management of chronic heel pain in olderpeople.Competing interestsHBM and KBL are Editor -in- Chief and Deputy Editor -in- Chief, respectively, of ... accurate for most conditions, it is generally less accurate for osteoarthritis, with a tendencyfor women to over-report and men to under-report [45].Thirdly, heel pain was documented as being present ... in 1900 by the German physicianPlettner, who coined the term Kalkaneussporn (calcanealspur) [1]. Although initially considered to be an abnormalfinding inextricably linked to heel pain, more...
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Báo cáo y học: "The patient perspective in research on major depression Pim Cuijpers" pps
... what patients with depressivedisorders need is still lacking. That is probably the mostimportant message from the paper by Barney, Griffithsand Banfield in BMC Psychiatry about information needsof ... prevention of major depressive disorder. This hugebody of research has resulted in extensive knowledgeabout major depressive disorders, what it is, who are atincreased risk of getting it, which processes ... depression. But wecurrently do have considerably more than a basic under-standing of what it is and how it can be treated.Despite these major advances of science in this field,very basic knowledge...
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Báo cáo y học: " Vitamin D status in female military personnel during combat training" ppsx
... of serum 25-hydroxyvitamin D and (B) parathyroid hormone levels in female Soldiers pre- and po st-basiccombat training by ethnicity. Serum 25-hydroxyvitamin D, 25(OH)D; parathyroid hormone, PTH; ... 1A).Ethnicity affected changes in vitamin D status(ethnicity-by-time interaction, P < 0.05); 25(OH)Ddecreased (P < 0.05) in non-Hispanic whites, and in Hispanic whites, but did not change in ... fracture incidence in military personnel. Although stress fracture is a health riskfor military personnel during training, no study has investigated changes in vitamin D status in Soldiers during...
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Báo cáo y học: " Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery" pps
... pro-inflammatory cytokines and reduced apoptosis bydecreasing TNF-α and Fas concentrations in plasma [15].Pentoxifylline probably prevents apoptosis both by inhib-iting TNF-α production and by diminishing ... neutrophil-mediatedlung injury and prevents EC dysfunction in several modelsof acute lung injury [12]. Pentoxifylline administration topatients with ischemic cardiomyopathy inhibited pro-inflammatory ... oxy-gen species in our model. The extrinsic pathway can beactivated during chronic ischemia via the release ofcytokines (e.g., TNF-α) and of other proinflammatoryinflammatory mediators in...
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