... JA,Davey RT, Rock Kress DM, Powers A, Beck I, Frenkel L, Baseler M,Coffin J, Fauci AS: A proof -of- concept study of short-cycleintermittent antiretroviral therapy with a once-daily regimen of didanosine, ... of the K103Nmutation should be ruled out even after m inimalexposures to EFV, reinforcing at the same time the needfor a systematic evaluation of GRT in naïve patients and after any type of ... significantly alter fitness of mutation-carrying quasispecies [16].This scenario confirms the result of Fox et al. 2008, and highlights the need to interrupt NNRTI-based regimenswisely. Patients of the...