... combined
chemotherapy and radiotherapy. Radioactive derivatives can also be used to evaluate
bioavailability of 4-HPR in vivo, using non-invasive imaging. In addition, the
peptidomimetic derivatives ... display significant
potency in all RT cell lines tested. Since iodo conjugation can potentially be used to
deliver radiotherapy and taken advantage of for radiation-...
... eradication therapy and the efficacy of chemotherapy.
Microbiol Immunol, 1997. 41: 7-12.
14. Gotoh A. , Kawakami Y. , Akamatsu T., and Katsuyama T.
Interaction of drugs for eradication therapy ... Pseudomonas aeruginosa, and three strains of Klebsiella
pneumoniae and two strains of Klebsiella oxytoca were also
investigated for the antibacterial evaluation study. They
w...
... results in the intracellular
accumulation and storage of the unprocessed glycosami-
noglycans (GAG), dermatan sulfate and heparan sulfate.
Patients with MPS I show variable clinical phenotypes, ... generation lentiviral vector was used to deliver
arylsulfatase A cDNA into the brain of metachromatic
leukodystrophy mice [21] and b-glucuronidase cDNA into
the brain of mucopolysac...
... 5'-
GCCAAGAGAATATCCG
AACT-3'
5'-
AGGCACAGTGGAACAA
GGACTTGT-3'
[GenBank:
NM_000584
]
60°C 78°C
Bovine MMP-1 5'-
CAAGAGCAGATGTGGA
CCAA-3'
5'-
CTGGTTGAAAAGCATG
AGCA-3'
[GenBank: ... establish
a standardised in vitro model of RA-related early cartilage
destruction with native, intact cartilage in order to analyse the
matrix-degrading capacity of...
... effect of drugs on PAF-AH activity was evaluated
in rabbit plasma. The in vitro enzymatic assay of plasma
PAF-AH was perfo rmed in the presence of several con-
centrations of each drug in the assay ... 8:17
http://www.journal-inflammation.com/content/8/1/17
Page 8 of 11
RESEARCH Open Access
In vitro anti-inflammatory and anti-coagulant
effects of antibiotics towa...
... effect of drugs on PAF-AH activity was evaluated
in rabbit plasma. The in vitro enzymatic assay of plasma
PAF-AH was perfo rmed in the presence of several con-
centrations of each drug in the assay ... enzymes in a concentration depended man-
ner (Figures 1 and 2), while only clarithromycin and azi-
thromycin induced an in vitro increase of rabbit plasma
PAF-...
... implications, including
the important application as chemo therapeutic and/ or
prophylactic agents of viral diseases of humans, lower
animals and marine animals, particularly in aquaculture
and conservation ... and extracts. YL
was the principle investigator of this project and designed and conceived of
the study, and participated in its coordination, and data analy...
... purposes)
Discussion
Several pharmacokinetic and pharmacodynamic parame-
ters, including bioavailability, receptor binding-affinity,
and elimination half-life contribute to the safety and effi-
cacy profile of ... Female
Race Hispanic Caucasian Caucasian
Cause of death Cerebrovascular Cerebrovascular Cerebrovascular
Medical history Healthy Healthy Healthy
Medications None None None...