Báo cáo y học: " Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary" potx
Báo cáo Y học: Activation of transcription of the human presenilin 1 gene by 12-O-tetradecanoylphorbol 13-acetate pdf
... Activation of transcription of the human presenilin 1 gene by 12 -O-tetradecanoylphorbol 13 -acetateMartine Pastorcic 1 and Hriday K. Das 1, 2 1 Department of Pharmacology & Neuroscience ... increases the rate of transcription initiation of the PS1 gene in SK-N-SH cellsTo determine whether the increase in the level of PS1mRNA results from the activation of the transcription of the gene ... eliminating the AP1 homology (m6) as wellas a point mutation abolishing the )10 Ets site (m1) (Fig. 5).M6 reduced the activity of the )11 8 to +17 8 construct by about twofold; however, the mutant...
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Báo cáo Y học: Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle docx
... for orphan receptors isseveral fold. First, the ability of a chemical structure to fitinto the ligand-binding pocket of an orphan receptor andthereby transcriptionally activate the orphan receptor ... Biochem. 269) 6035 Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle Yong Xu1, Fang Fang1, YanXia Chu1, Davy Jones2,* and Grace ... methylepoxyfarnesoate activation of the 4DR12Core promoter isdue to the effect of the C472A/H475L mutations on the ligand-binding activity of USP.Some models of nuclear hormone receptor action include the component...
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Báo cáo Y học: Activation of a covalent outer membrane phospholipase A dimer pptx
... 2002 Activation of an OMPLA dimer (Eur. J. Biochem. 269) 2181 Activation of a covalent outer membrane phospholipase A dimer Roelie L. Kingma and Maarten R. EgmondDepartment of Membrane Enzymology, ... atthe dimer interface are located at more than 15 A ˚from thecatalytic calcium ion (Fig. 1B). In the standard assay, wild-type OMPLA has a calcium affinity of 12 lMwith a maximum activity of around ... Calcium-dependent glutaraldehyde cross-linking of dimer inter-face variants. Lane 1, molecular mass marker; lane 2 and 3,Leu32 fi Ala/Leu71Ala/Leu73Ala variant; lane 4 and 5, Gln94Alavariant; lane 6 and 7,...
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Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx
... is properly cited.AbstractThe efficiency of activating latent transforming growth factor(TGF)-β1 in systemic lupus erythematosus (SLE) may control thebalance between inflammation and fibrosis, ... Consequential dysregulation of B cell activity leads to production of systemic lupus ery-thematosus (SLE)-like autoantibodies [3] and development of a lupus- like illness, resulting in early death at ... ActivityIndex (SLEDAI) [12]. Therapy was recorded, including currentdose of steroids and antimalarial drugs. Damage wasassessed using the American College of RheumatologySLICC (Systemic Lupus International...
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Báo cáo y học: "Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury" potx
... injury in vivo in miceA figure showing modulation of the BMP and WNT pathway after mechanical injury in vivo in mice. Modulation of BMP and WNT pathway after mechanical injury in vivo in mice. 7 ... mouse model of joint surface injury.Taken together, these data show modulation of the BMP and WNT pathways following mechanical injury in vitro and in vivo,which may play a role in the reparative ... upregulation of BMP- 2mRNA after injury. Several factors can determine activation of BMP signaling independently of the expression of one ligand,including secretion and solubility of the ligand(s),...
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Báo cáo y học: "Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study" pot
... of data, statistical analysis, and manuscriptpreparation. NA participated in acquisition of data, analysis and interpretation of data, statistical analysis, and manuscriptpreparation. JMP and ... citation purposes)Vol 9 No 6Research articleActivation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing ... catabolic factors in OA cartilage, includingmetalloproteinase (MMP)-1 and MMP-13 and the inflammatorymediator cyclooxygenase 2 (COX -2) , as well as the PAR -2- activated signalling pathways in...
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Báo cáo y học: "Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium" docx
... CentralPage 1 of 12(page number not for citation purposes)Journal of Circadian RhythmsOpen AccessResearchGlycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link ... the pathophysiology of affective disorders [6]. While there aremany differences in the molecular and genetic details of the circadian machinery in mammals and Drosophila, the basic regulatory principles are ... [21,53].Mathematical modeling of the mammalian circadian oscillator feedback loops has shown that extreme delays(~7 hr) can be achieved by varying the nuclear import rate of the PER/CRY complex, and...
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Báo cáo y học: "Activation of monocytes and cytokine production in patients with peripheral atherosclerosis obliterans" docx
... 8:23http://www.journal-inflammation.com/content/8/1/23Page 7 of 7 Plasma levels of pro and anti-inflammatory cytokinesPlasma levels of IL-6, TNF-a and IFN-g were significantlyhigher in patients; t he levels of the anti-infl ammatorycytokines IL-10 ... expression of adhesion molecules of the endothelium and synthesis of other pro-inflammatorycytokines such as IL-1 and IL-6.Similar to results regarding pro-inflammatory cytokines,high levels of anti-inflammatory ... 8:23http://www.journal-inflammation.com/content/8/1/23Page 6 of 7 in peripheral blood, t he objectives of the present studywere to evaluate the plasma levels of anti-inflammatory and inflammatory cytokines including interleukin-6 (IL-6),...
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Báo cáo y học: " Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?" ppsx
... primary research commentaryreviewreports primary researchReview Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness ... characterized by airway inflammation,exaggerated airway reactivity to contractile agonists, and a decrease in β-adrenoceptor-mediated airway relaxation,remains a common cause of pulmonary morbidity ... homeostasis and/or force generation.TNF receptor 1 signaling pathways that areactivated in airway smooth muscle cellsTNF receptor- associated factor- 2–nuclear factor κκB pathway TNF-α activates...
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Báo cáo y học: "Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2" pptx
... lung fibrosis develops in the absence of MCP-1 or CCR2To determine whether Aspergillus antigen- induced airway fibrosis develops in the absence of MCP-1 or CCR2, wemeasured lung hydroxyproline ... of 12(page number not for citation purposes)Respiratory ResearchOpen AccessResearchAspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis ... to the reported requirement for CCR2 in the development of bleomycin-induced pulmonary fibrosis, suggests that different cell types and mediators may beoperational in allergen-induced airway fibrosis...
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Báo cáo y học: " Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways" pot
... synthesis [4,5]. In the present study we therefore tested the hypothesis that acti-vation of the SPHK/S1P signalling pathway may contrib-ute to MR-dependent regulation of peripheral airwaydiameter. ... of 14(page number not for citation purposes)Respiratory ResearchOpen AccessResearch Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of ... Figs. 5C,D, 6).DiscussionMR signaling pathways play a key role in the regulation of airway resistance which is determined largely by the diam-eter of smaller, intrapulmonary airways [25]. A betterunderstanding...
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Báo cáo y học: "Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model" pptx
... purposes)RetrovirologyOpen AccessResearchActivation and detection of HTLV -I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat modelTakashi Ohashi*, Mika Nagai, Hiroyuki Okada, Ryo ... Ohashi T, Hanabuchi S, Kato H, Koya Y, Takemura F, Hirokawa K,Yoshiki T, Tanaka Y, Fujii M, Kannagi M: Induction of adult T-cellleukemia-like lymphoproliferative disease and its inhibition by ... ohashi-t@igm.hokudai.ac.jp; Mika Nagai - purefood@igm.hokudai.ac.jp; Hiroyuki Okada - hiro1230@igm.hokudai.ac.jp; Ryo Takayanagi - coffea-arabica@igm.hokudai.ac.jp; Hisatoshi Shida - hshida@igm.hokudai.ac.jp*...
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Báo cáo y học: " Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary" potx
... gamma-aminobutyric acid(GABA). The disinhibition of dopamine-containing neu-rons in the ventral tegmental area (VTA) allows them torelease dopamine in the NAc and (via amygdala) in cer-tain parts of the ... purposes)Theoretical Biology and Medical ModellingOpen AccessReview Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward ... block-ade of naturally required DA release at the NAc.Gabapentin is a gamma-aminobutyric acid (GABA) ana-logue, with GABAmimetic pharmacological properties.Gabapentin is used for the treatment of...
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Báo cáo y học: "EMS-physicians’ self reported airway management training and expertise; a descriptive study from the Central Region of Denmark" docx
... except the Airtraq and the ILMA areavailable in all sizes from neonatal to large adult. Forconfirmation of correct laryngeal tube placement allunits hav e capnography available, and all ha ve ... maintenance and quality controlfor emergency medical service personnel. The aim of this study was to provide data regarding airway management- training and expertise from the regional physician-staffed ... procedures may be neededas the lack of equipment awareness may pose a threatto patient safety. The physicians training with the airway devices isin general satisfactory and in line with what hasbeen...
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Báo cáo y học: "An annotated cDNA library and microarray for large-scale gene-expression studies in the ant Solenopsis invicta" pot
... those involved in other interestingbehaviors and traits. Unfortunately, in ants such studies havebeen seriously constrained by the lack of sequence data and other molecular tools. The majority ... research interactions informationOpen Access2007Wanget al.Volume 8, Issue 1, Article R9MethodAn annotated cDNA library and microarray for large-scale gene-expression studies in the ant Solenopsis ... relative to the Drosophila genome. Alternatively, these gene categoriesmay simply be biased in cDNA libraries relative to genomes, for instance, because they contain mainly highly or mainlylowly expressed...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnphysician who specializes in the study and treatment of the disorders of the stomach and intestinesbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015