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Theoretical Biology and Medical
Modelling
Open Access
Research
Bringing metabolic networks to life: convenience rate law and
thermodynamic constraints
Wolfram Liebermeister* and Edda Klipp
Address: ... (14).
The convenience kinetics resembles other rate laws
To check whether the convenience kinetics yields any
unusual results, we compared it to two e...
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() ... and proteomic data.
The structure of the metabolic system (i.e., stoichiometries and enzyme regulation) needs to
be known, and the reac...
... 1-
13
C-phenylalanine and d
5
-phenylalanine was per-
formed with hourly blood sampling. Following gas chro-
matograph and mass spectrometry analysis, data from this
study showed that, in contrast to ... hemorrhage only group. Upon
stabilization, stable isotope infusion was performed in all
three groups, followed by blood drawn hourly and subse-
quent gas chromatography mass spectrome...
... exposure to exoge-
nous glucocorticoids may lead to clinical Cushing's syn-
drome and suppression of the hypothalamic-pituitary-
adrenal (HPA) axis which may last from nine months to a
year ... acetonide while they were also
receiving the fixed-dose combination of emtricitabine and
tenofovir plus ritonavir and atazanavir. They had no his-
tory of concomitant inhaled, intranas...
... Coronary artery aneurysm: a review. Prog
Cardiovasc Dis 1997, 40:77-84.
4. Gurtu R, Uemura H, Tsuda E, Dubrey SW: Giant coronary artery aneurysms
and myocardial infarction: aetiology and management. ... 4).
Conclusions
Coronary artery aneurysms may be complicated by
thrombosis and rupture. The optimal treatment
options of coronary aneurysms are still largely debated.
They include antico...
... such
as diarrhoea and vomiting [2]. Colchicine toxicity relates
to its cellular anti-mitotic action and preferentially affects
tissues that have a rapid turnover [3], leading to early gas-
trointestinal ... Colchicine toxicity-clinical features and
treatment. Massive overdose case report. J Toxicol Clin Toxicol
1995, 33:71-77.
5. Naidus RM, Rodvien R, Mielke H Jr: Colchicine toxicit...
... integrase inhibitor. It had been previously tested in
our lab and showed no visual cytopathic effects or any
cytotoxicity at 20 μM (data not shown). U373-MAGI
cells, primary macrophages, and PBL were ... so they are thought to play a crucial role in
viral persistence, latency, and dissemination [4,5].
Early steps of HIV-1 infection include viral entry by
binding to the main receptor...
... European
Community Respiratory Health Survey. Effect of passive
smoking on respiratory symptoms, bronchial responsive-
ness, lung function, and total serum IgE in the European
Community Respiratory Health ... between ETS score and
respiratory symptoms adjusting for age, sex, SES score,
parental allergy, occupational exposure to other respira-
tory pollutants, and pack years (for ex-da...
... depressive symptoms
approached psychotic intensity and in addition she had
orofacial dyskinesia. She was advised to stop procyclidine
and to commence venlafaxine up to 225 mg daily: she had
failed to ... consciousness) and a one year his-
tory of epilepsy. He had mild depressive symptoms but no
psychotic symptoms at any point. He was taking 75 mg
chlorpromazine, 10 mg amitriptyl...
... antibody; CDR = complementarity-determining region; CR = complement receptor; Crry = complement receptor 1-related protein y; CTLA-4 =
cytotoxic T-lymphocyte antigen 4; DHEA = dehydroepiandrosterone; ... A (Table 1
and Additional File 1) was found to decrease inflammatory
cytokine production by splenocytes and reduce renal disease
[43]; suberoylanilide hydroxamic acid was also shown t...