Báo cáo y học: " Research Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkers" pdf
Báo cáo y học: " Research Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkers" pdf
... al., Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkers Theoretical Biology and Medical Modelling 2010, 7:14Budu-Grajdeanu et al. Theoretical Biology and Medical ... 7:14http://www.tbiomed.com/content/7/1/14Open Access RESEARCH Research Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkersPaula Budu-Grajdeanu1, Richard C ... clinically and withlaboratory tests every two months regardless of disease activity, and provided blood, a 24hour urine specimen, and a freshly voided urine specimen at the visit. Renal and nonre-nal...
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Báo cáo y học: "An optimization framework for unsupervised identification of rare copy number variation from SNP array data." doc
... and collected theresults for analysis. GY, MK and TL developed methodology for in silico analysis of the results and GY analyzed the results.MG did the MLPA validation of the not previously ... term. More specifically, inthe absence of copy number variation, is 2.0 for an AAgenotype, for an AB genotype, and 0 for a BB genotype.The fitting procedure yields estimates for the model parameters.We ... the Affymetrix platform, and Quan-tiSNP is designed for data obtained from the Illumina plat-form. Therefore, Birdseye, PennCNV, and ÇOKGEN'ssuperior performance compared to dChip and QuantiSNP...
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Báo cáo y học: "A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets" pptx
... contributionsCC and MG conceived and designed the study. CC and KKY performed thefull analysis. CC, KKY, KYY, RA, JR, CS and MG wrote the manuscript.Received: 21 December 2010 Revised: 26 January 2011Accepted: ... a variety of species ranging fromyeast to human. More specifically, we show that chro-matin features can accurately predict t he expressionlevels of genes and collectively account for at least ... of Molecular Biophysics and Biochemistry, Yale University, 260Whitney Avenue, New Haven, CT 06520, USA.2Department of ComputerScience and Engineering, The Chinese University of Hong Kong, Rm...
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Báo cáo y học: "The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics" ppt
... Molecular Biophysics and Biochemistry, Yale University,266 Whitney Ave, New Haven, CT 06511, USA.5Department of Genetics,Stanford University School of Medicine, Alway M344, Stanford, CA 94305,USA.6Program ... Biology and Bioinformatics, Yale University,266 Whitney Ave, New Haven, CT 06511, USA.Authors’ contributionsTG designed the experiments and completed the analysis. AA and TGdeveloped the formalism. ... proteinphosphorylation in yeast. Nature 2005, 438: 679-684.23. Yip KY, Yu H, Kim PM, Schultz M, Gerstein M: The tYNA platform for comparative interactomics: a web tool for managing, comparing and mining multiple...
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Báo cáo y học: "A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis" pot
... mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesisEvgeniya A Oshchepkova-Nedosekina* and Vitalii A LikhoshvaiAddress: Institute of Cytology and Genetics ... the active site of a conformationally dynamicenzyme by directed mutation. Role of dynamics in structure-function correlations in Escherichia coli adenylosuccinatesynthetase. J Biol Chem 1998, ... In 1963 Wyngaarden and Greenland [6] proposed that ASUC is a competitive inhibitor of both IMP and ASP, and GMP is a competitive inhibitor of both IMP and GTP.Theoretical Biology and Medical...
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Báo cáo y học: "A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose" pptx
... not for citation purposes)Theoretical Biology and Medical ModellingOpen Access Research A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as ... determined in prelim-inary cytotoxicity assays: 5 mM 3-AB, 100 µM NU1025 and 3 µM PJ34.Clonogenic survival assayClonogenic survival assays were carried out using the flowcytometric cell-sorting ... thestudy, developed and performed the statistical analysis and helped to draft the manuscript. All authors read and approved the final manuscript.References1. Belzile JP, Choudhury SA, Cournoyer...
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Báo cáo y học: "A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH" ppt
... 17(page number not for citation purposes)Theoretical Biology and Medical ModellingOpen Access Research A mathematical model for LH release in response to continuous and pulsatile exposure ... (GnRH) is released bythe hypothalamus in a pulsatile fashion and stimulatesluteinizing hormone (LH) and follicle stimulating hor-mone (FSH) release by pituitary cells by a complex seriesof ... frequency and concentrationhave marked (nonlinear) influences on the release of LH and FSH. The purpose of our work is to use mathematics and machine computation to understand the dynamics ofthis...
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Báo cáo y học: " PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation" potx
... binding profiles is widely used for such pur-poses [9], yet provides merely a fraction of the informationnecessary to support the research community. An excellent and extensive comparison of ... laboratory will maintain PAZAR for the long-termas it is necessary for our on-going research, ideally the projectwould expand through the engagement of a cooperative research community. Recent ... only onePAZAR central concept: analysis and input/output systemFigure 2PAZAR central concept: analysis and input/output system. The sequences and transcription factors are stored independently...
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Báo cáo hóa học: " Research Article Models for Gaze Tracking Systems Arantxa Villanueva and Rafael Cabeza" doc
... the one hand, an alternative human com-puter interaction technique for activities where hands canbarely be employed and, on the other, a solution for dis-abled people who maintain eye movement ... used a system composed of three cameras and two sources of differently polarized light. Yoo and Chung[10] employ five infrared lights and two cameras. Shih and Liu [11] use two cameras and three ... by means of the eyemore and more realistic. Research in gaze tracking systemsdevelopment and applications has attracted much attentionlately. Recent advancements in gaze tracking technology...
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Báo cáo y học: "A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins" ppsx
... Nakayama EE, Yokoyama M, Sato H, Levy JA, Shioda T: A singleamino acid of the human immunodeficiency virus type 2 capsid affectsits replication in the presence of cynomolgus monkey and human TRIM5alphas. ... virological analysesin vitro. MY and HS performed structure modeling analyses. HY and MKexamined viral genome sequences. NI and TM analyzed the data and wrotethe paper. All authors read and approved ... Microbiology, Yokohama City University School of Medicine,3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan.Authors’ contributionsNI and TM designed the study. NI, HT, and AR performed virological...
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