Báo cáo y học: "The burden of sepsis-associated mortality in the United States from 1999 to 2005: an analysis of multiple-cause-of-death data" pptx
Báo cáo y học: "The burden of sepsis-associated mortality in the United States from 1999 to 2005: an analysis of multiple-cause-of-death data" pptx
... 1Research The burden of sepsis-associated mortality in the United States from 1999 to 2005: an analysis of multiple-cause -of- death dataAlexander Melamed1 and Frank J Sorvillo21Keck School of ... contribution to the analysis and interpreta-tion of data for this study. We are also grateful to the Los Angeles County Department of Public Health and to the Department of Preven-tive Medicine of the ... calculation of age-specific rates andratios were: less than 1 year, 1 to 4 years, 5 to 14 years, 15 to 24 years, 25 to 34 years, 35 to 44 years, 45 to 54 years, 55 to 64 years, 65 to 74 years, 75 to...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... (39.6%) and a lowcontent for alanine (6.5%). Thus, the alanine and glycinecontent of WSM was rather similar to that of EDTA-IM. In spite of the presence of mineral, it was possible to analyze the ... Fourier transforminfrared spectroscopy (FTIR) and X-ray diffraction analyses of mineral and organic matrix during heating of mother of pearl(nacre) from the shell of the mollusc Pinctada maxima. ... Hydroxyproline, hydroxy-lysine and phosphoserine were not detected in WSM, WIM,EDTA-SM and EDTA-IM. The comparison of the amino acid composition of the main peak obtained from AE-HPLC of WSM and...
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Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx
... found in many inflammatory disorders, including hepatic disease,multiple sclerosis, transplant rejection and inflammatorybowel disease [4]. Analysis of synovial tissue, synovial fluidand peripheral ... modulating migration directly, chemokines canstimulate cells to release (pro)inflammatory mediators suchas cytokines and matrix metalloproteinases [3]. Increasedexpression of inflammatory chemokines ... compartmentalization in lymphoid tissuesunder non-inflammatory conditions [2].Most chemokines play a role in inflammatory conditions byinducing integrin activation, chemotaxis, and angiogenesis.Apart from...
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Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... therapy for PAHincreases the importance of diagnosis and monitoring of thiscomplication. Furthermore, since many principles of PAHmanagement translate to the management of RP, this raises the ... activity [5]. Endothelin receptorantagonists (ERA) are in the vanguard of these new manage-ment strategies. Phosphodiesterase (PDE) type V inhibitors,angiotensin-converting enzyme inhibitors and ... at1 year and 2 years of 96% and 89% compared withViewpointCold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertensionFrances C HallUniversity of...
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Báo cáo y học: "MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis" pps
... purposes)Figure 5Inhibitory effects of neutralizing antibodies to cytokines on the SF-mediated proliferation capacity of RA FLSsInhibitory effects of neutralizing antibodies to cytokines on the SF-mediated ... pathogenesis of RA.IntroductionSynovial tissue from healthy individuals consists of a singlelayer of synovial cells without infiltration of inflammatory cells. In rheumatoid synovial tissue, lymphocytes ... addition of GM-CSF. These results indicatethat GM-CSF in SF is important in the hyperproliferation of RAFLSs. In contrast, in the microarray analysis, semiquantitativeRT-PCR and Western blot analysis...
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Báo cáo y học: "Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection" docx
... purposes)Reconstruction of Tooth and Bone in Tokyo Medical and Dental Univer-sity to TMu, and by a grant from the Japan Society for the Promotion of Science (18591657) to IS. Hyaluronan was distributed by Seikagaku ... proteoglycan synthesis and can pre-vent its release from the cell matrix [16,27]. Hyaluronan alsosuppresses the production and activity of proinflammatorymediators and proteases as well as altering ... previously reported that serum kera-tan sulfate increased sharply 1 day after injection of chymopa-pain into the knee joint in rabbits [26]. The serum keratansulfate also sharply decreased, and these...
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Báo cáo y học: "Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity" pdf
... continuous self-repair and regeneration,remain to be identified. We investigated the capacity of repair of chondrocytes by analyzing their ability to initiate an anabolicresponse subsequent to ... points. Proteoglycans in the cartilage were visualized using Alcian blue staining, the same dye used in the S-GAG assay. The control articular car-tilage explants (shown in the bottom row of ... of the proteoglycan content. Interestingly, articular cartilage cul-tured alone in the absence of cytokine induction lost 50% of proteoglycan compared with that to the MI control. comparedto...
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Báo cáo y học: "AIT test has no problem in the detection of anti-ribosomal P" ppsx
... name of the autoimmune target (AIT) test and it participates in the qualitycontrol program run by the Korean Society of LaboratoryMedicine [3]. In 1999 and 2007, reports of antinuclearantibody ... [4,5]. Furthermore, the AIT test can indirectly help in the diagnosis of SLE using the microtubule organizing center pattern (MTOC) that can onlybe observed in the IT-1 cell line [4].We investigated ... (anti-Rib-P) in the pictures they revealed. In addition to the anti-Rib-P that Mahler and colleagues mentioned, limitations of the HEp-2 cell line in the detection of autoantibodies such asanti-Ro...
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Báo cáo y học: " AIT test has no problem in the detection of anti-ribosomal P – authors’ response" docx
... systematic study is mandatory to compare the sensitivityand specificity of the AIT test for the detection of anti-Rib-Pantibodies and other antibody specificities using a variety of contemporary diagnostic ... arelatively insensitive technique for the detection of humanautoantibodies when compared with other techniques suchas ELISA and western immunoblotting (WB). In an example relevant to the anti-Rib-P ... human macrophagecell line (IT-1) in an autoimmune target (AIT) assay to predict the presence of anti-ribosomal P (anti-Rib-P) antibodies [1],based on a previously described cytoplasmic and/ornucleolar...
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Báo cáo y học: " Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity" potx
... in the thyroid glands. The ability of cancerous thyroid cells to actively transport iodide via NIS has provided a uniqueand effective delivery system for the detection and destruc-tion of these ... functionally expressed in thyroids, salivaryglands, gastric mucosa, and lactating mammary glands [1].NIS mediates the active transport of iodide into the folli-cular thyroid cells and, in turn, ... primer, the second-strandedDNA was synthesized, and the double-stranded DNAwas then transformed into E. coli NM522 strain to allow the mutated strand to be amplified. The full-length NISmutant...
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