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Báo cáo y học: "Vulnerability to High Risk Sexual Behaviour (HRSB) Following Exposure to War Trauma as Seen in Post-Conflict Communities in Eastern Uganda: A Qualitative Study" pps

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Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"

... manuscript, and participated in the acquisi-tion of data. AZ participated in the coordination of the study.AAZ participated in the design of the study, and performed thestatistical analysis. RA conceived ... production was enhanced byIL-4 and IL-5, and suggests a T-helper lymphocyte type 2cytokine activation in response to sepsis after traumatic injury.Eosinophils normally account for only 1% to 3% of ... butprocalcitonin is known to be among the most promising sepsis markers in critically ill patients, and is capable of complement-ing clinical signs and routine laboratory variables that are sug-gestive...
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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"

... Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have the following features: (a) the ability to deliver transgenes in a highly efficient ... applied to humans. The purpose of this paper is to consider the potential for applying the available genetic modification (GM) technologies to the goal of achieving human germline gene therapy. ... International Publisher. All rights reserved Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline Review/Analysis Received: 2004.3.24 Accepted: 2004.5.14...
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Báo cáo Y học: The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier ppt

Báo cáo Y học: The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier ppt

... indicators forsensor proteins such as ArcB, BvgS and EvgS. As the quinones are the only components of the respiratory chainwhich apparently are free in their movement within the membrane, they ... histidine kinases may either be the consequence of a decrease in the histidine kinase activity, or, alternatively, of an increase in an intrinsicautophosphatase activity present in the BvgS and EvgS proteins ... SDS/PAGE analysis the relative amount of the phosphorylated histidine kinases was determined by Phos-phorImage analysis. The figure shows representative autoradiographs of the samples after SDS/PAGE...
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Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

... providing an additional contact with the SH2 domain of SOCS-3 involving R94. A conforma-tional change induced by the phosphorylation of tyrosine Y4 31 may also contribute to the increase in binding affinity compared ... subtracted nonspecific binding. Determination of the dissociation constant wascarried out by Scatchard analysis [22].Peptide precipitation assay and immunoblot analysisApproximately 0.15 lmol of ... discuss the phosphorylation of tyrosine Y5 81 creating a more favourable conformation of the sequence surrounding the tyrosines Y5 79 and Y5 81, therebyincreasing binding affinity. Interestingly, the...
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Báo cáo Y học: Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK potx

Báo cáo Y học: Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK potx

... (A)AlignmentsoftheHsPIIwithEcPIIand HsPII with EcGlnK amino-acidsequences. The identity (73%) and similarity(86%) of HsPII to EcPII is higher than HsPII to EcGlnK (67% and 76%, respectively).Secondary ... and similarity (83%)of HsPII to EcPII is higher than that of HsPII to EcGlnK(67% and 76%, respectively), HsPII is structurally closer to EcGlnK or EcGlnK-ATP and EcPII-ATP (Figs 1B and2A). The ... unpublisheddata). This protein was called GlnK because it has higheridentity to EcGlnK than EcPII and it is encoded by a glnK gene which is located on the glnKamtB operon. The HsPIIand HsGlnK proteins...
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Báo cáo y học: "Postictal psychosis: presymptomatic risk factors and the need for further investigation of genetics and pharmacotherapy" doc

... purposes)Annals of General PsychiatryOpen AccessCase reportPostictal psychosis: presymptomatic risk factors and the need for further investigation of genetics and pharmacotherapyEric M Morrow*1, ... I. Symmetry and convergence of the corticocorticalconnections of the left and the right principal sulcus (PS) and the left and the right supplementary motor area (SMA) in the rhesus monkey. Cereb ... experts.Recent insight into the genetics of primary psychotic dis-orders such as schizophrenia may lead hypotheses into the susceptibility and pathophysiology of PIP which isalso discussed...
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Báo cáo y học: "Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes" ppt

... small-molecule inhibitor of the binding of insulin-like growth factor (IGF) -1 to IGF -binding proteins, on 12 5I-labeled IGF -1 binding to human osteoarthritic chondrocytesEffect of NBI- 317 72, a small-molecule ... articlePharmacological disruption of insulin-like growth factor 1 binding to IGF -binding proteins restores anabolic responses in human osteoarthritic chondrocytesFrédéric De Ceuninck 1 , Audrey Caliez 1 , Laurent ... small-molecule inhibitor of the binding of insulin-like growth factor (IGF) -1 to IGF -binding proteins, on 12 5I-labeled IGF -1 binding to human osteoarthritic chondrocytes. Confluent chondrocytes were incubated...
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Báo cáo y học: "Anti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritis" pdf

... 3Research articleAnti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritisGilles Boire1, ... at inclusion and with increasing age, charac-terized a subgroup of patients with more rapid and more severe joint damage. In contrast, anti-CCP antibodies were not independently associated with ... include antibodies targeting cyclic citrullinated peptide (CCP) [20] and antibodies targeting in vivo citrullinated pro-teins, such as anti-keratin antibodies, antiperinuclear factor,anti-citrullinated...
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Báo cáo y học: "Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele" docx

... http:/ /arthritis- research.com/content/7/6/R1200R1200Vol 7 No 6Research article Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor ... seronegative for rheumatoid factor. Transmission, percentage of heterozygous 1858C/T parents transmitting the 1858T allele. The plan was to test the hypothesis for RF+ RA; analysis for all RA ... reproduction in any medium, provided the original work is properly cited.Abstract The protein tyrosine phosphatase nonreceptor type 22(PTPN22) gene encodes for lymphoid tyrosine phosphatase LYP, involved...
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Báo cáo y học: " ICU Cornerstone: High frequency ventilation is here to stay" pptx

... mechanical ventilation. Keywords acute lung injury (respiratory distress syndrome, adult), high- frequency ventilation, hypercapnia,respiratory distress syndrome (infant), respiratory physiology 345Available ... airwaysurgery, ensured that high- frequency positive pressure ventilation and certainly HFJV did find a niche in clinicalCommentary ICU Cornerstone: High frequency ventilation is here to stayPeter C RimensbergerClinical ... respiratory distress syndrome; HFJV = high- frequency jet ventilation; HFO = high- frequency oscillation; ICU = intensive care unit;PEEP = positive end-expiratory pressure.Critical Care October...
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Báo cáo y học: "Is obesity a risk factor for low back pain? An example of using the evidence to answer a clinical question" ppsx

... risk factor for low back pain? An example of using the evidence to answer a clinical questionTimothy A Mirtz* and Leon GreeneAddress: University of Kansas, Department of Health, Sport, and Exercise ... retrieve the data should anyonewish to examine the source. As an example of an evidence summary see Table 2.It is at this time that the clinician is ready for the final step of applying the evidence. ... basic research appeared to conclude what wasalready intuitively thought about low back pain andincreased weight.Body mass indexBefore an in-depth discussion of low back pain and obes-ity...
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Báo cáo y học: "Vulnerability to High Risk Sexual Behaviour (HRSB) Following Exposure to War Trauma as Seen in Post-Conflict Communities in Eastern Uganda: A Qualitative Study" pps

... Sexual Behaviour (HRSB) Following Exposure to War Trauma as Seen in Post-Conflict Communities in Eastern Uganda: A Qualitative Study Wilson Winstons Muhwezi1Đ, Eugene Kinyanda2*, Margaret ... vulnerability narrative, context of trauma and sexual behaviour, explanatory models of sexual behaviour in a post-conflict setting, and impact of conflict-related trauma on sexual behaviour as domains ... training was to ensure that they gained ability to get exhaustive and in- depth data about study participants’ full stories regarding the sexual behaviour. Each data collection session was tape-recorded...
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Báo cáo y học: " Formation of translational risk score based on correlation coefficients as an alternative to Cox regression models for predicting outcome in patients with NSCLC" doc

... translational risk score based on correlation coefficients as an alternative to Cox regression models for predicting outcome in patients with NSCLC. Theoretical Biology andMedical Modelling 2011 8:28.Kössler ... collective and can hardly be repeated with distinct cohorts. Whereas the pre-dictive power of any single variable including tumour size was limited, integration of molecular i nformation into a unifying ... MMP2 polyclonal rabbit anti-body (Biomol). As secondary antibody we used biotinylated goat anti-rabbit for Cox2 and MMP2, goat anti-mouse for CD68, and rabbit anti-goat for Notch3 and GAS 6 (allobtained...
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Báo cáo y học: "Peer-reviewed, high quality, worldwide information on all topics relevant to child and adolescent mental health" ppt

... AccessEditorialPeer-reviewed, high quality, worldwide information on all topics relevant to child and adolescent mental healthJoerg M Fegert1 and Benedetto Vitiello*2Address: 1University of ... Editorial Child and Adolescent Psychiatry and Mental Health is a new,peer-reviewed, scientific journal devoted to the rapid dis-semination of high- quality reports relevant to mental health of children ... fieldof child and adolescent psychiatry and mental health psy-chiatry is closely associated with various allied disciplines.Interdisciplinary collaboration, however, has been hin-dered by the...
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Báo cáo y học: "Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats" potx

... Landsberger et al.: Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats.Critical ... 14:R223http://ccforum.com/content/14/6/R223Page 8 of 8 RESEARC H Open AccessInhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia ... endotoxin-induced intestinal leukocyte adhesion. Therefore, thisreceptor may represent a novel target for the modula-tion of the inflammatory response within the microcir-culation in sepsis.Key...
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