... proteolysis in cultured L6myotubes. Shock 1998, 10:298-306.39. Yin HN, Chai JK, Yu YM, Shen CA, Wu YQ, Yao YM, et al: Regulation of signaling pathways downstream of IGF-I/insulin by androgen in ... are among the most widely used drugs in the world and are effective in the treatment of manyinflammatory and immune diseases. However, one of the main side-effects of systemically administered ... an increase in muscle mass probably mediated by inhibition of muscleproteolysis rather than by stimulation of muscle proteinsynthesis [27]. Inhibition of muscle proteolysis, in parti-cular the...