... patients with severe traumatic brain injury, and to evaluate the adverse effects of treatment. Methods This was a prospective, randomized, cohort studycomparing two treatments: pentobarbital and thiopental.Patients ... patients in thepentobarbital group. Although this incidence may be greaterthan that in previous studies [10], we attribute this to the defi-nition of hypotension used (detection at any time ... death in nine patients, vegetative state in two, severedisability in two, moderate disability in four and good recovery in four. In the pentobarbital group, the 6-month outcome wasdeath in...