... HoraÂkovaÂ1, Ivo SyrovyÂ1, Saverio Cinti2 and Jan KopeckyÂ11Department of Adipose Tissue Biology and Center for Integrated Genomics, Institute of Physiology,Academy of Sciences of the Czech ... development of obesityby both, increasing energy expenditure and d ecreasing in situlipogenesis. In order to further analyse consequences of respiratory uncoupling in white fat, the eects of the ... studied.Reduction of adiposity by respiratory uncoupling in adipocytes may be limited by mitochondrial oxidativecapacity. Importantly, it has been sho wn in vitro [42] thatthe uncoupling, induced by ectopic...