... DNA-binding proteins TRF1, TRF2 and Pot1 involved in telomere capping functions. The expression of hTERT, encoding the catalyticsubunit of telomerase, plays a crucial role in the control of lymphocyte ... For instance,Pot1, a single-stranded telomeric DNA-binding protein,behaves as a terminal transducer of the cis-inhibitory effect of the TTAGGG-repeat-binding protein TRF1 [6]. The shelterin ... telomerase and the telomeric DNA-binding pro-teins TRF1, TRF2 and POT1 in normal, activated as well as in HTLV-1 infected and in Tax-expressing T lymphocytes.They therefore plead for a regulatory mechanism...