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Báo cáo y học: "Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro" ppsx

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Báo cáo y học: " High blood pressure, antihypertensive medication and lung function in a general adult population"

... BBLintake on lung function mainly in patients with alreadyexisting pulmonary diseases. The association between blood pressure, antihypertensive drug treatment and limited lung function in a population-based ... high blood pressure and antihypertensive medication classes (Model 1-3), mutual exclusive categories (Model 4,5, 5a) and high blood pressure and antihypertensive medication as individual variables ... detailedanalysis of antihypertensive medication indicates that BBL medication and not any other antihypertensive medication is associated with a reduced lung function. This negativeeffect of BBL medication...
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Báo cáo y học: "A Comparison of Immuncapture Agglutination and ELISA Methods in Serological Diagnosis of Brucellosis"

... found in our study were higher in comparison to the study in question but specificity is lower. This situation may be related with the phase of the brucella infection. In a study conducted by ... agglutination methods. Different results may be obtained depend-ing on the nature of anti-globulin. This situation has an effect on the sensitivity, specificity and ultimately applicability of ... various clinics were included in the study and kept at -70ºC until per-forming laboratory study. Coombs anti-brucella test (Vircell, S.L., Spain), ELISA Ig G and Ig M (Vircell, S.L., Spain) and...
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Báo cáo y học: "Strength training improves muscle quality and insulin sensitivity in Hispanic older

... 4(1):19-27 â Ivyspring International Publisher. All rights reserved Research Paper Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes ... Tournis S, Leontsini D, et al. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. J Clin Endocrinol Metab. 2005;90:5970-7. ... of high-intensity strength training on muscle quality and whole-body insulin sensitivity in a high risk population of older adults with diabetes. This is why we chose to conduct this investigation...
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Báo cáo y học: "Comparative study of serum Na+ and K+ levels in senile cataract patients and normal individuals"

... changes in aqueous electrolytes levels and effect on lens metabolism and probably cataract formation. In this paper, we study serum level of Na+ and K+ in senile cataract patients and normal individuals. ... AAbbssttrraacctt Many factors such as aging, changes in blood electrolytes levels, and possibly family history are involved in senile cataract formation. Changes in serum electrolytes levels can induce ... Methods and materials: 155 senile cataract patients scheduled for cataract surgery in eye clinic of Rasoul hospital and 155 normal individuals were selected. Serum Na+ and K+ levels were...
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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

... splicing inhibition by tetracycline is n egligible (Fig. 2). The sixfold stron ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by thesubstitution, ... [31].RESULTSErythromycin, Cl-tetracycline and streptomycin inhibit nuclear splicing in vitro The effects of eight different antibiotics (the aminoglycoside,kanamycin, the a minocyclitol glycoside, streptomycin, ... RNA by 9%only (lane 3). T he other three antibiotics, Cl -tetracycline,streptomycin and erythromycin, are clearly inhibitors of nuclear pre-mRNA splicing, as indicated by a largereduction in...
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Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf

... analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile Sudeep Bhattacharyya, Amy Kerzmann and Andrew L. FeigDepartment of Chemistry, Indiana ... thesetoxins has been studied previously [12,13]. TcdA and TcdBshare 43% homology and 63% similarity and aremembers of a family of cytotoxins known as the largeclostridial cytotoxins that also ... of fluorescent analogs of thenucleotide sugar complexes for use in studying glycosyl-transferases in general and TcdA in particular. These substrate analogs are related to the commercially availablemethylanthraniloyl...
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Báo cáo y học: "α α Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis" pps

... haematoxylin and eosin stained sections.Immunohistochemistry for HIF-1 α and HIF-2 α expressionThe HIF- and HIF- proteins were detected usingESEE 122 (IgG1monoclonal antibody [mAb]; ... significant.ResultsHIF- α expression in synovial lining cellsHIF- and HIF- expression was both cytoplasmic and nuclear in arthritic synovial tissues (Fig. 1a,b). The medianpercentage of synovial lining cells ... expressing HIF-1 α and HIF-2 α proteins in normal, rheumatoid, and osteoarthritic synoviumNormal (n = 22) OA (n = 34) RA (n = 22)HIF- HIF- HIF- HIF- HIF- HIF- Minimum 0.00 0.00 20.00...
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Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx

... high and constant level of c-Myc. Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc byphosphorylation of the serine 62 residue in the N-terminal of c-Myc [24]. They ... determine if c-Myc transcriptioninhibitor obstructed the effect of TGF1, and (3) determine the role of ERK1/2 in stabilizing the expression of c-Myc. Materials and methodsAntibodies and reagentsRecombinant ... hypothesizedthat c-Myc plays a central role in TGF1 signaling for cellgrowth stimulation. Additionally, to examine the possibility of involvement of the MAPK pathway in regulation of c-Myc sta-bility, we...
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Báo cáo y học: "Strong inhibition of TNF-α production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor" ppt

... signifi-cantly inhibited at nanomolar concentrations of RWJ 67657, and mRNA expression was also decreased, by nearly 50% at 10 nM. Inhibition of p38 MAPK activity leadsto reduced TNF-α mRNA expression ... biosynthesis. Nat Cell Biol 1999, 1:94-97.21. Bhattacharyya A, Pathak S, Datta S, Chattopadhyay S, Basu J,Kundu M: Mitogen-activated protein kinases and nuclear fac-tor-kappaB regulate Helicobacter pylori-mediated ... undercontrol of the p38 MAPK route. Inhibition of the p38 MAPKroute may inhibit production not only of TNF-α, but also of otherinflammatory mediators produced by macrophages, and indirectly of inflammatory...
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Báo cáo y học: "Negative regulation of cytokine signaling and immune responses by SOCS proteins" potx

... family of proteins, suppressor of cytokine signaling (SOCS) proteins, is an importantnegative regulator for cytokine signaling [6,7].CIS /SOCS family: structure and actionmechanism SOCS and cytokine- inducible ... gp130, Tyr985 of the leptin receptor and Tyr401 of the erythropoietinreceptor, Tyr729 of the granulocyte colony-stimulating factor(G-CSF) receptor, Tyr800 of the IL-12 receptor and Tyr985 of the ... and activators of transcription 3) and suppressor of cytokine signaling 3 (SOCS3 ) in macrophages. SOCS3 stronglysuppresses STAT3 activated by IL-6/gp130 but not by IL-10, because SOCS3 does not...
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Báo cáo y học: "Prostaglandin I2 enhances cough reflex sensitivity to capsaicin in the asthmatic airway" pps

... [20,21].Although cysteinyl leukotrienes (cLTs) play an importantrole in bronchomotor tone of the asthmatic airway, theirrole in cough reflex sensitivity is controversial [19,22].These findings indicate ... with the clearance of the tracheobronchial mucus,may occur via increased cough reflex sensitivity. Inflam-matory mediators such as prostaglandins may adjust the cough reflex sensitivity. However, ... in cough reflex sensitivity in the asthmatic airway. Further studiesmay be required to elucidate the role of PGI2 in othereosinophilic bronchial disorders presenting with non-productive cough...
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Báo cáo y học: " AIDS epidemic at age 25 and control efforts in China" ppsx

... thatthe AIDS epidemic will be effectively controlled in China in the same way as her past successful history of control- ling other infectious diseases. At the same time, whatremains concerning ... govern-ment providing free testing and treatment, people livingwith HIV /AIDS and people at risk are now voluntarilyseeking testing and collaborating more frequently withhealth care workers. Since the ... China's AIDS control program and had a pro-found impact even far beyond the AIDS field. The newpolicy reconnects prevention and treatment, long lostchain in AIDS control work in China....
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Báo cáo y học:

Báo cáo y học: "Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro" ppsx

... significant increase in cytokine production (Figure 1d).Combination of glucose and insulin on cytokine releaseTo determine whether the hyperglycemic effect on cytokine release seen in Figures 1a and ... in humangranulocytes.Results Increasing concentrations of both glucose and mannitolsignificantly enhanced LPS-induced cytokine production. Insulinalone did not alter cytokine production and ... Hyperglycemia may lead to inflammation byenhancing cytokine production via the direct effects ofhyperosmotic stress. Impaired phagocytosis and oxidative burstunder hyperglycemia may weaken defense...
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Báo cáo y học:

Báo cáo y học: "Hyperglycemia may alter cytokine production and phagocytosis by means other than hyperosmotic stress" pdf

... The inability of mannitol to induce an increasedCommentaryHyperglycemia may alter cytokine production and phagocytosis by means other than hyperosmotic stressCharles E WadeUS Army Institute ... intensive insulin therapy (IIT) in critically illpatients. They suggested that hyperglycemia via hyperosmolarity atsupra-physiological levels potentiates the production of cytokines by peripheral blood ... granulocytes and found the responses reducedwith hyperglycemia. They postulated that the efficacy of IIT may be due, at least in part, to the correction of hyper-osmolality induced by the lowering...
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Báo cáo y học: "Early stress exposure: Concepts, findings, and implications, with particular emphasis on attachment disturbances" pptx

... for citation purposes)Child and Adolescent Psychiatry and Mental HealthOpen AccessReviewEarly stress exposure: Concepts, findings, and implications, with particular emphasis on attachment ... Psychi-atry 1988, 145:1-10.6. Belsky J, Fearon RM: Early attachment security, subsequentmaternal sensitivity, and later child development: does con-tinuity in development depend upon continuity ... caseof attachment disturbances, one good context for studying early risk and intervention, sizablequestions remain about conceptual models and assessment practices.Conclusion: Implications of...
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