... articleAlteration of serotonin transporter density and activity in fibromyalgiaLaura Bazzichi1, Gino Giannaccini2, Laura Betti2, Giovanni Mascia2, Laura Fabbrini2, Paola Italiani2, Francesca ... multicase families with fibromyal-gia syndrome. J Rheumatol 1999, 26:408-412.33. Yamamoto S, Ouchi Y, Onoe H, Yoshikawa E, Tsukada H, Taka-hashi H, Iwase M, Yamaguti K, Kuratsune H, Watanabe Y: ... depression and anxiety [3]. The cause and pathophysi-ology of FMs is unclear; pathophysiological hypothesesinclude impairment in the functioning of the hypothalamic-pitu-itary axis and alterations...