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Báo cáo y học: "Decision maker views on priority setting in the Vancouver Island Health Authority" docx

Báo cáo y học:

Báo cáo y học: "Decision maker views on priority setting in the Vancouver Island Health Authority" docx

... priority setting proc-ess?8 What role have physicians played in priority setting/ resource allocation processes in the past? How would youwant the physicians to be involved in the priority ... survey of key decision makers. Health Pol-icy 2002, 60:39-58.15. Teng F, Mitton C, MacKenzie J: Priority setting in the provincial health services authority: survey of key decision makers.BMC Health ... and Views of Priority Setting Decision-Mak-ers. Health Policy 2002, 61:279-290.8. Jan S: Institutional Considerations in Priority- Setting: Trans-action Cost Perspective on PBMA. Health Economics...
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Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx

... 18:11http://www.jbiomedsci.com/content/18/1/11Page 6 of 10low taurine concentrations ≤ 10-7M. Therefore, the neuronal pathway involved in acid secretion induced bylow taurine concentrations may predominantly involve in ... con-centration in stomach by binding to GABAAreceptors on cholinergic neurons, resulting in the excitation ofcholinergic neurons, followed by the release of ACh. The ACh-binding M3receptors exist on ... antagonist, completelyinhibited the acid secret ion induced by taurine at ≤ 10-7M, but only a certain extent of the secretion induced bytau rine concentrations > 10-7M (Figure 5B). The...
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Báo cáo y học: " Ventilator-induced endothelial activation and inflammation in the lung and distal organs" docx

... occursimultaneously in the lung, liver and kidney, and imply thatrelease of inflammatory mediators into the circulation is prob-ably not the only cause of augmented endothelial activation orinflammation in ... stretch may cause endothelial activation in healthy mice, not only in the lung but also in organs distal to the lung. To determine endothelial activation in these organswe assessed de novo synthesis ... 2Ventilator-induced endothelial activation and inflammation in pulmonary tissueVentilator-induced endothelial activation and inflammation in pulmonary tissue. In total lung homogenates, mRNA expression...
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Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps

... cells. The second aim of the study was to determine whetherdownregulation of phagocyte activities are involved in the anti-inflammatory activity of anti-TNF-α therapy. The lack ofactivity on phagocytosis, ... down-regulation of phagocyte activity may be involved in the mechanism of action of anti-TNF-α therapy [9].BSA = bovine serum albumin; C3Zy = C3-coated zymosan; FMLP = N-formyl-methionyl-leucyl-phenylalanine; ... maintain anadequate antimicrobial host defence capacity. On the otherhand, the inhibitory activity of the mAb on CD69 membraneexpression on neutrophils indicates that these cells areamong the...
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Báo cáo y học: "Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production" ppt

... elucidated.ConclusionWe conclude in this study that the increased expression ofCD147 on monocytes/macrophages in RA may beresponsible for elevated MMP secretion, cell invasion and the CyPA-mediated ... of these cellsalone. CD147 antagonistic peptide had some inhibitory effect on MMP production and cell invasion in the co-culture. In the cyclophilin A (CyPA)-mediated cell migration assays, the ... TIMP-1) and blank contrast (RA blank) in the lining and sublining layers in RA synovium (× 400). The bottom two images show the expression of CD147 in anky-losing spondylitis (AS CD147) and...
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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt

... difference in the meta-analysis. The overall pooled anal-ysis included the mean changes of the FVC and the DLCOafter 12 months of therapy obtained from the observationalstudies and from the CYC experimental ... the original work is properly cited.AbstractIntroduction The purpose of the present study was tosystematically review the effect of cyclophosphamide treatment on pulmonary function in patients ... pulmonary function. Since none of the patientsincluded in these studies were selected on the basis of pro-gression of ILD or the time from the SSc-related ILD diagnosis,further randomized clinical...
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Báo cáo y học: " Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed " pot

... analyses, and in the preparation and finalization of the manuscript. AvW and KN were involved in the analysis and interpretation of these post hoc analyses and in the preparation and finalization ... interpretationof these post hoc analyses, and in the preparation and finalization of the manuscript. JP was involved in the design and oversight of the trials, the analysis and interpretation of these ... provided by bothMerck and Pfizer Inc. The conduct of these studies (including the design,data collection and analysis, and interpretation) was supported by Merckand by Pfizer Inc. The analyses...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects

Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"

... largely responsible for the consistency of the active component that can act as a barrier to the spread of any bacteria penetrating the tissues including those of the periodontium. It is conceivable ... to the desired consistency, by regulating the blood and saline volume. In fact, the Hyaloss® matrix has a dual function: on one hand its physiochemical properties facilitate the application ... regenerative therapy as a coadjuvant of autologous bone grafting. In contact with the patient's blood or saline solution, the Hyaloss® matrix forms a gel almost instantly, thus facilitating the...
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Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx

Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx

... inhibition of the protein synthesis in rabbit reticulocyte lysate [30]. The (2–5)A synthetasereaction products were also confirmed by MALDI-MSand by NMR analysis [31]. We succeeded in cloning the sponge ... known to stronglyinhibit protein synthesis i n s ponge cells [22], it is concludedthat the (2–5)A synthetase system is involved in defenseagainst microorganisms, very likely by inhibition of cellproliferation ... (2–5)A synthetase the sponge specimens might protectthemselves against microbial infection or inhibition of cellproliferation and finally may undergo apoptosis. The existence of cytokines in sponges...
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Báo cáo Y học: A novel gain-of-function mutation of the integrin a2 VWFA domain docx

Báo cáo Y học: A novel gain-of-function mutation of the integrin a2 VWFA domain docx

... developed by the addition of ABTS reagent as above.RESULTS The E318W mutation in a2 increases collagen binding The introduction of the mutation F302W into aM has beenshowntoresultinagainoffunctioninboththeisolatedaMVWFA ... chain of E318 forms a hydrogen bondwith R288 in the closed form, and this bond is brok en on moving to the open form. The loss of the hydrogen bond in the E318I /Y/ W mutations, coupled with the ... position F302 in aM led toan increase in ligand binding, increased binding of anantibody associated with aMb2 activation, and a n increase in the proportion of active integrin [ 36]. This indicates...
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