... Sekiya I, Tsuji K, Koopman P, Watanabe H, Yamada Y, ShinomiyaK, Nifuji A, Noda M: SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a car-tilage-derived ... RNeasy clean-up (Qiagen, Mississauga, ON, Can-ada) as per the manufacturer's directions. Total RNA wasquantified spectrophotometrically. High-quality RNA for use in the microarray analysis ... extracellular space determined that many of the protein products of these genes were involved in a variety of activities, including chemokine/cytokine activity – includingmacrophage Csf-1 – and various...