Báo cáo y học: " Ventilator-induced lung injury and mechanotransduction: why should we care" pot

... clinician you may ask why 30 ml/kg of tidal volume wasused in this study and you may note that oxygen was usedfor ventilation. These injurious regimens have been less (if atall) used clinically. ... hyperoxia, and MIP-2 production in ventilator-induced lung injury. J Appl Physiol 2002, 93:517-525.8. Luo J, Manning BD, Cantley LC: Targeting the PI3K-Aktpathway in human cancer: rationale and promise. ... Tremblay L, Cassivi SD, Bai XH, Mourgeon E, Pierre AF,Slutsky AS, Post M, Keshavjee S: Alterations of nitric oxide syn-thase expression and activity during rat lung transplantation.Am J Physiol Lung...

Báo cáo y học: " Postresectional lung injury in thoracic surgery pre and intraoperative risk factors: a retrospective clinical study of a hundred forty-three cases" pptx

... lung resection [1]. Respiratory complications remain themajor cause of morbidity and mortality following lung resection. Acute lung injury (ALI) and acute respiratorydisease syndrome (ARDS) are responsible ... 4patients underwent lobectomy or bilobectomy; and 1patient underwent sublobar resections. The mortalityrate with ALI was highest after pneumonectomy(33.3%), followed by lobectomy ( 25%) and sublobarresections ... respiratory dysfunction syndrome (ARDS), defined as acute hypoxemia accompanied byradiographic pulmonary infiltrates without a clearly identifiable cause, is a major cause of morbidity and mortalityafter...

Báo cáo y học: "Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study" pdf

... lung injury. Methods: The effects of intratracheal ATP on lung permeability, edema or lung inflammation wereassessed by measurements of the lung wet-to-dry weight ratio and lung permeability ... ventilator-induced lung injury. BackgroundAcute lung injury and acute respiratory distress syndromeare major causes of acute respiratory failure, and are char-acterized by pulmonary edema, neutrophil ... P 2Y 2 and P 2Y 4 receptors to promote the production ofinflammatory cytokines associated with lung injury. Involvement of ATP in mechanical lung injury Worsening or induction of acute lung injury...

Báo cáo y học: "Regional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury" potx

... breathing activity during ven-tilatory support in acute lung injury (ALI) may improvepulmonary gas exchange, systemic blood flow, and oxygensupply to the tissues [1]. Most importantly, spontaneousbreathing ... mean airway pressures and minute volumes. Gas exchange, hemodynamics, and inspiratory effort were determined and dynamic computed tomography scans obtained. Aeration and ventilation were calculated ... acute lung injury; injury, after induction of acute lung injury. The contributions of spontaneous and controlled breaths to BIPAP+SBmean were weighted by their respective rates (weighted mean)....

Báo cáo y học: "Acute lung injury, overhydration or both" doc

... high pulmonary capillary wedge pressure [8].The key question is therefore whether radiographicpulmonary mechanical and gas exchange abnormalities,CommentaryAcute lung injury, overhydration or ... ALI/ARDS may be loose, poorlyreproducible, relatively insensitive and nonspecific, and highlytherapy-dependent. Overhydration is particularly difficult torecognize. Additional diagnostics may be ... arbitrary; it may be too high and thereby result in the erroneous diagnosis of ALI/ARDS when,in fact, the lungs are flooded by overzealous crystalloids,infused to combat presumed hypovolemia or hypotension.Indeed,...

Báo cáo y học: " Acute lung injury outside the ICU: a significant proble" ppsx

... directly involvingthe lung, progression to ALI can be rapid.Acute lung injury (ALI) and its extreme manifestation, theacute respiratory distress syndrome (ARDS) complicate awide variety of ... medical and surgical conditions, not allof which affect the lung directly [2]. ALI and ARDS aredefined by varying degrees of refractory hypoxemia seen inassociation with bilateral lung infiltrates ... condition afflicts the lung directly or indirectlyseems to influence lung compliance and recruitment, appear-ances on computed tomography, and possibly clinicaloutcome [7,8]. However, epidemiological...

Báo cáo y học: "Severe endothelial injury and subsequent repair in patients after successful" ppsx

... FITC-CD45 and anti-mouse PE-IgG serving as control, respectively. Tubes were analyzedby flow cytometry analysis. Cells larger than the countingbeads and with at least the granularity of lymphocyteswere ... ofsecondary disorders including pulmonary disease, and renal and liver insufficiency (Table 1).All measurements were also performed in healthy con-trols (nine in the CEC and EMP study and five ... (PCI). On the second dayafter PCI and in controls who did not receive PCI, bloodwas drawn by venopuncture. Samples were drawn slowly,handled carefully and analyzed immediately after sam-pling....

Báo cáo y học: "2009 H1N1 Influenza and Experience in Three Critical Care Unit"

... 38039, Kayseri, Turkey 3. Konya Educuation Research Hospital Pulmonary Diseases and Critical Care Unit, 42040, Konya, Turkey 4. Erciyes University Department of Infectious Diseases, 38039, Kayseri, ... Doganay4, Ibrahim Erayman5, Kursat Uzun1 1. Selcuk University, Meram Medical Faculty, Pulmonary Diseases and Critical Care Department, 42080, Konya, Turkey 2. Erciyes University Department of ... data of critically ill patients with Influenza A 2009 (H1N1) reveals that relatively younger pa-tients are affected by the disease. Fever and respira-tory symptoms were cardinal symptoms of disease...

Báo cáo y học: "Synchronous primary intrapulmonary and mediastinal thymoma-A case report" pot

... Sen Wei, Jun Chen*, Qinghua Zhou*Abstract We report an extremely rare case of Synchronous primary intrapulmonary and mediastinal thymoma in a Chinesepatient. We describe the histological and ... compon ent and are very rare[2].Here we present a successfully resected case of synchro-nous primary intrapulmonary and mediastinal thymom awith vascular reconstruction.Case reportA 55-year-old ... cava.Microscopically according to the WHO classification,the mediastinal tumor(MT) was a B3/B2 primary thy-moma and the mass in the upper lobe of right lung ismainly a B3/B2 primary intrapulmonary thymoma(PIT)with...

Báo cáo y học: " Role of ADAM and ADAMTS metalloproteinases in airway diseases" pot

... breathless-ness) and airway obstruction. Hallmarks of asthma aremainly airway hyperresponsiveness caused by a wide vari-ety of stimuli and airway inflammation involving eosi-nophils and mast cells. ... in asthmatic air-ways and human embryonic lungs. Am J Respir Crit Care Med2005, 171(9):958-965.56. Yang Y, Haitchi HM, Cakebread J, Sammut D, Harvey A, Powell RM,Holloway JW, Howarth P, Holgate ... phenotype [60].Recently, we demonstrated that ADAM-8 is overexpressedin lungs from mice experimentally exposed to allergens and that the depletion of ADAM-8 by the use of KO ani-mals or by immunodepletion...

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