... to ribose
5-phosphate (Figure 6–3 ).
a. Ribose 5-phosphate provides the ribose and deoxyribose sugars found in
nucleotides.
76 USMLE Road Map: Biochemistry
N
Table 6–1 . Energy yield in anaerobic ... mobilized source of glucose to provide
for the short-term needs of the body.
78 USMLE Road Map: Biochemistry
N
Table 6–2 . Regulators of enzyme activity in glucose metabolism....
... otherwise.
DOI: 10.1036/007 144 2057
USING THE
USMLE ROAD MAP SERIES
FOR SUCCESSFUL REVIEW
What is the Road Map Series?
Short of having your own personal tutor, the USMLE Road Map Series is the best ...
N
LANGE
USMLE
ROAD MAP
BIOCHEMISTRY
RICHARD G. MACDONALD
Department of Biochemistry and Molecular Biology
University of Nebraska Medical Center
Omaha, Nebraska
WIL...
... is frequently lethal soon after birth.
14 USMLE Road Map: Biochemistry
N
CLINICAL
CORRELATION
CLINICAL
CORRELATION
CLINICAL
CORRELATION
34 USMLE Road Map: Biochemistry
N
V
max
V
i
1
2
V
max
0
0
[S]
Positive
... their normal function, leading to cell death and conse-
quent neuropathy.
24 USMLE Road Map: Biochemistry
N
Table 3–1 . Examples of enzyme replacement the...
... portion of fructose to be excreted in the urine.
86 USMLE Road Map: Biochemistry
N
CLINICAL
CORRELATION
CLINICAL
CORRELATION
102 USMLE Road Map: Biochemistry
N
5. The answer is A. This patient exhibits ... equation:
Pyruvate + 4 NAD
+
+ FAD + GDP + P
i
→ 3 CO
2
+ 4 NADH + 4 H
+
+ FADH
2
+ GTP
2. One of the carbons of pyruvate is released as CO
2
during the formation of
ace...
... possible
problems:
– Hepatic dysfunction leading to decreased bile acid synthesis.
– Severe ileal disease leading to malabsorption of bile salts.
– Obstruction of the biliary tract.
116 USMLE Road Map: Biochemistry
N
No ... begins (Figure 9–2 ).
c. The free ammonia that is utilized in the initial step is derived by deamina-
tion of glutamine by glutaminase or glutamate de...
... is most likely defective?
A. Base excision repair
B. Mismatch repair
1 64 USMLE Road Map: Biochemistry
N
2. The tRNAs are 6 5–1 10 nucleotides long and their backbones fold back to
allow for intramolecular ... have recently been developed for treatment of diseases involving farnesylated proteins.
1 74 USMLE Road Map: Biochemistry
N
CLINICAL
CORRELATION
CLINICAL
CORRELATION
B...
... affected
persons in this pedigree indicate age of diagnosis.
196 USMLE Road Map: Biochemistry
N
I
II
III
67
61 37 51 57
54 44 43 38
4. What type of molecular phenomenon is most likely responsible ... retardation.
186 USMLE Road Map: Biochemistry
N
Male
Female
Affected
Unaffected
Deceased
Obligate carrier
Marriage or mating
Consanguinity
Proband
12 34
12 345
12 3
123
45 67...