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Báo cáo y học: "HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex" pdf

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Báo cáo toán học: "Sets of integers that do not contain long arithmetic progression" pot

... cannot apply the CLT to an interval that is shrinking as rapidly as ±δ. We getaround this by applying the CLT to an interval that shrinks very slowly, and then using ananalytic form of the ... lemma plays the role that “a line intersects a sphere in at most two points” played for Behrend, and that “adegree D polynomial curve intersects a sphere in at most 2D points” played for Rankin.Green ... spheres that contain many lattice points, which isa fundamentally number theoretic issue that they handled with the pigeonhole principleand the circle method, respectively. Here, as in Green...
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Báo cáo y học: "Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells" pot

... were incubated with the primary antibody forone h after which they were then rinsed. Staining was car-ried out using the streptavidin-biotin kit (Dakocytoma-tion); the primary antibodies used ... significantly increased uponSAHA treatment for 24 and 48 h. In addition, the percen-tage of cells in the G0 /G1 phase was significantly inhibitedby SAHA treatment. These data suggest that SAHAinduced ... significantly inhibited their growth by 50% as compared to that of the control. Fluorescence-activated cell sorting analysis demonstrated significant inhibition of cell cycle progression(sub -G1 arrest) ...
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Báo cáo y học:

Báo cáo y học: " Impact of race on efficacy and safety during treatment with olanzapine in schizophrenia, schizophreniform or schizoaffective disorde" pdf

... patientsexperiencing clinically significant weight gain (defined asan increase from baseline ≥7% at anyt ime) was 36.1% in the black patient group compared to 30.4% in the whitepatient group (P = .021)Since ... subgroups. Another study looked at the impact of race on the efficacy and safety of long-act-ing risperidone compared to placebo [26]. These resultsshowed there was no effect of race on the improvementof ... therapeutics and identifying patients who will have the optimal response with minimal adverse events eitherbefore the treatment initiation or early in the course oftherapy. The field of genomics,...
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Báo cáo y học: " Newly described human polyomaviruses Merkel Cell, KI and WU are present in urban sewage and may represent potential environmental contaminants" potx

... polyomaviruses in environmentalmatrices.Competing interests The authors declare that they have no competing interests.Authors' contributionsSBM coordinated the study, concentrated urine ... studying the excreted strains, prevalence and transmission of these recently described polyomaviruses.FindingsHuman polyomaviruses JC and BK (JCPyV and BKPyV) are two members of the Polyomaviridae ... MCPyV in the developmentof MCC [18]. Recent serological data show that KIPyV,WUPyV and MCPyV are prevalent in the healthy popula-tion [19].Antibodies against lymphotropic polyomavirus (LPyV),a...
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Báo cáo y học: " Tenascin-C and alpha-smooth muscle actin positive cells are increased in the large airways in patients with COPD" pot

... negative for desmin. In the minority of cases the a-SMA positive cells were positivealso for desmin, which may suggest the other knownphenotype for myofibroblast [25]. Interestingly, a-SMApositiv ... membrane of the bronchialepithelium; Tn-C (b): staining present as in Tn-C (a)and in the stroma underneath the basement membrane;Tn-C (c):stainingpresentasinTn-C (b) and in the wider area of the connective ... beyond the basement membrane area. Laitinenand co-workers analyzed also the number of eosinophilsand lymphocytes, but did not found any correlationbetween the amount of these inflammatory...
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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt

Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt

... used to make the column, showing that itis not interacting directly with the antibodies linked with the column but is possibly very tightly associated with the PsCCaMK. There are other examples ... changes in ([Ca2+]cyt) [6,8]. The information through ([Ca2+]cyt) is transduced by twomain pathways, one involving CaM and CaM-relatedproteins, and the other involving CDPKs. Both of thesepathways ... binding ofTGA3 to the Arabidopsis CaM3 promoter. A study by vander Luit et al. [16] showed that distinct calcium signalingpathways that operate during cold (predominantly cyto-plasmic) and wind...
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Báo cáo y học:

Báo cáo y học: " Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis" ppt

... present in the inflamed synovium,especially in the synovial fluid. Because granulocytes havea lifespan of only about 3 days, they will die in largenumbers at the site of inflammation, which may ... citrulline staining in about half of the RApatients studied but in none of the control individuals.However, the staining pattern they observed was quitedifferent from that in the study conducted ... abundant in the RA synovium, it is not surprising that citrullinated vimentin is present in the synovium as well. Indeed, the Sa antigen, which wasrecently identified as citrullinated vimentin [21],...
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Báo cáo y học: "Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritis" pot

... only the joint-of-interest in Exercise I; in the remaining six cases, the two independent readers did not score repair in the joint-of-interest, which was in agreementwith the judgement of the ... that the technical factors in capturing the image are identical. It isentirely possible in the early stages of developing an erosion that, if the inflammatory process is completely halted, the ... standard scoring method whowere not aware that they were seeing repair because the timeorder was concealed.Competing interests The authors declare that they have no competing interests.Arthritis...
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Báo cáo y học:

Báo cáo y học: "New data favouring that neurotrophins are of importance in arthritis" pot

... these are present in the synovial tissue and on chondrocytes. The importance of neurotrophins in joints should be further studied,including examinations on the efficacy of interfering with theireffects ... of NGF in the inflamed peripheral joint. Nevertheless, the authors do not rule out the possibility that fibroblast-likesynoviocytes can produce NGF under certain circumstances.These findings ... NGF was not expressed in fibroblast-like synoviocytes, as seen by ELISAanalysis on culture supernatant. The authors concluded that infiltrating T lymphocytes and myeloid cells are the mainsources...
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Báo cáo y học:

Báo cáo y học: "Two different genomes that produce the same result" docx

... site that suppressed the effect of the first) with another round of mutagenesis, restoring lysozyme activity. e amino acids encoded by the DNA between the two mutations should, in theory, have ... extent they are transcribed in the same groups and in the same temporal order during development in the two species. Almost all genes are regulated during development, either up or down. e synchrony ... find that the two genomes retain certain gross similarities - both are remarkably AT-rich - but the coding and intergenic sequences have diverged. e questions they then ask are: Do the two...
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