Báo cáo y học: "Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection" pdf
Báo cáo y học: "Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection" pdf
... purposes)RetrovirologyOpen AccessResearchMechanisms of HIV non -progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression ... TAHIV cohort after 20 years of infec-tion [7].Early studies on this cohort of TAHIV patients led to theidentification of the Sydney Blood Bank Cohort (SBBC) of long-term survivors [8], and ... Clinical School, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia, 3Centre for Immunology, St. Vincent's Hospital and University of NSW, Sydney, NSW, Australia, 4Retroviral...
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Báo cáo y học: "Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor" potx
... by reperfusion injury (Raynaud's phenomenon) and the inflammatory process appear to play a key role inSSc [14].Calcium-channel blockers, particularly those of the dihydro-pyridine type ... capacity to hemoglobin. Systolic pulmonary artery pressure was deter-mined by Doppler echocardiography, and left ventricularejection fraction, by radionuclide ventriculography. The control ... according to thecriteria of LeRoy and colleagues [18]. The exclusion criteriawere the impossibility of stopping vasodilator therapy,pregnancy, current cigarette smoking, diabetes, associa-tion with...
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Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt
... periphery b lood, and they could produce proinflammatory cytokines to increase the b-actin protein levels in glial cells (such asastrocytes) in the injury penumbra.Delayed treatment with chondroitinase ... 7:1668-1687.22. Yang CS, Tzou BC, Liu YP, Tsai MJ, Shyue SK, Tzeng SF: Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by theaddition of antioxidants and the reduction of intracellular ... addition, astrocytes becomereactivated with an increase in number and hypertrophy,a process so called as gliosis. The event forms glial scar to prevent the spread of injury factors and to inhibit...
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Báo cáo y học: "Reduced trabecular bone mineral density and cortical thickness accompanied by increased outer bone circumference in metacarpal bone of rheumatoid arthritis patients: a cross-sectional study" ppt
... objective of this study was to assess three-dimensional bone geometry and density at the epiphysis and shaft of the third meta-carpal bone of rheumatoid arthritis (RA) patients in comparison to healthy ... fund of the Depart-ment of Rheumatology, Inselspital Bern, and a personal grant by the Böni Foundation to D. Aeberli.Author Details1Department of Rheumatology and Clinical Immunology/Allergology, ... se-lecting the area with a lowerthreshold of 40 mg/cm3 and an upper threshold of 280mg/cm3 HA density after smoothing the image (con-tourmode 3 and peel mode 1, and contour mode 1 and peelmode...
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Báo cáo y học: "The relationship between twitch depression and twitch fade during neuromuscular block produced by vecuronium: correlation with the release of acetylcholine" ppsx
... increase transiently after therelease of ACh, reach a peak, and subsequently declinedue to hydrolysis of free ACh. We assigned a first-orderrate constant for hydrolysis of ACh (khydrolysis) at 12000 ... release of ACh intoa synaptic cleft, ACh binding to two sites at a single post-synaptic receptor, and ACh hydrolysis. The number of ACh molecules released by the first stimulus was postu-lated to ... producedexclusively by increased [D] and, hence, an increasedoccupancy of the postsynaptic receptors. On the otherhand, the decrease in T4 is caused by a combination of increased postsynaptic receptor...
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Báo cáo hóa học: " Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)" potx
... KC, Collins PL: Effects of nonstructural proteinsNS1 and NS2 of human respiratory syncytial virus on inter-feron regulatory factor 3, NF-kappaB, and proinflammatorycytokines. J Virol 2005, ... shown to act coopera-tively to suppress the activation and nuclear translocation of the IFN-regulatory factor IRF-3 [4,47], and antagonizetype I IFN activity by inhibiting the type I IFN and ... Respira-tory syncytial virus infection of human airway epithelial cellsis polarized, specific to ciliated cells, and without obviouscytopathology. J Virol 2002, 76(11):5654-66.67. Zhang W, Yang...
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Báo cáo y học: "Relationship between inflammatory markers, metabolic and anthropometric variables in the Caribbean type 2 diabetic patients with and without microvascular complications" pptx
... Thestudy includes 162 subjects (male and female) of which44 were of healthy individuals, 44 patients with type 2diabetes, 44 patients with type 2 diabetes and nephropa-thy and 30 diabetics with ... 162 subjects of which 44 were healthy individuals, 44 were of type 2 diabetes, 44 were of type 2 diabetes with nephropathy and 30 were of diabetes with retinopathy. Simultaneously urine samples ... complica-tions and improve not only the life expectancy, but thequality of life of these patients.Materials and methodsThis was a case -control study [8] comparing the concen-trations of inflammatory markers...
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Báo cáo y học: "Mechanisms of Degranulation in Neutrophils" pdf
... domain of receptors(receptor tyrosine kinases) or as cytosolic enzymes(nonreceptor tyrosine kinases). The src family of nonreceptor tyrosine kinaseshas been implicated in the control of exocytosis ... exocytosis of primary and secondarygranules in neutrophils.15-Arrestins are a group of cytosolic phosphoproteins that were previouslycharacterized for their role in endocytosis of lig- and- bound ... degranulation, or exocytosis, of membrane-bound secretory granules. The neutrophil alsopossesses the capacity to release a diverse array of antimicrobial proteins and enzymes intracel-lularly into membrane-bound...
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Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps
... factor),proteases, and prostaglandin E2(PGE2) [30]. Synthesis of the inflammatory cytokines IL-1 and TNF-α and expression of their receptors are enhanced in OA [29–31]. Bothcytokines have been shown to ... high- and low-MW HA Yes YesSuppressed lymphocyte stimulation Darzynkiewicz & Balazs, Human lymphocytes; various MWs and doses of HA Yes Yes1971 [86]Inhibited macrophage phagocytosis and ... significantly less with HA with a MW of 2.02 × 106than HA with a MW of 9.5×105 [102]. Similarly, the histology of articular carti-lage and synovial tissue was significantly better with anHA of MW...
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Báo cáo y học: "Mechanisms of oral tolerance revisited" pps
... mice.Functionally, they inhibit collagen type II-specific T cellproliferation and pro-inflammatory Th1 cytokine production, and more importantly, induce the generation of collagen typeII-specific ... identification of the role of IDO-expressing DCs opensanother avenue to explore the possibility to treat humanautoimmunity and chronic inflammatory conditions by ‘preven-tive’ vaccinations in an antigen- specific ... Puccetti P: The combined effects of tryp-tophan starvation and tryptophan catabolites down-regulate Tcell receptor zeta-chain and induce a regulatory phenotype innaive T cells. J Immunol 2006,...
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