Báo cáo y học: " RNA silencing and HIV: A hypothesis for the etiology of the severe combined immunodeficiency induced by the virus" pot
Báo cáo y học: " RNA silencing and HIV: A hypothesis for the etiology of the severe combined immunodeficiency induced by the virus" pot
... mRNA (at the 3' end of HIV genomic RNA or mRNA) and suggests the capacity for RNA interference (RNAi). The RNAi pathway beginswith long double-stranded RNA, which are naturally gen-erated ... microRNAs and HAAmiRNAs, as discussed above(Figure 3c). In mammals, maturation of miRNAs is initi-ated by nuclear cleavage of longer primary miRNA tran-scripts by the Drosha RNAse III endonuclease ... viral microRNAs(vmiRNAs) named the HIVaINR antisense RNA miRNAsor HAAmiRNAs [14]. Others have suggested the possibil-ity for HIV microRNAs encoded by the sense strand of HIVmRNAs with the potential...
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Báo cáo y học: " Valproic acid and HIV-1 latency: beyond the sound bite" ppsx
... eliminated by enfuvirtide and VPA? Viral RNA clearance has two phases of decay [8].Does the population of latently infected CD4+ T-cells havesimilarly complicated kinetics?Others have tried ... that Dr. Margolis and colleagues are correct, and that HIV reservoirs can be eliminated through the additional administration of a small molecule, such asVPA. However, the challenge of eradicating ... Kovacs JA, Polis MA,Walker RE, Falloon J, Masur H, Gee D, Baseler M, Dimitrov DS, FauciAS, Lane HC: HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART)...
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Báo cáo y học: "Psychological stress and fibromyalgia: a review of the evidence suggesting a neuroendocrine link" pps
... 34:1209-1217.2. Aronoff GM: Myofascial pain syndrome and fibromyalgia: a critical assessment and alternate view. Clin J Pain 1998, 14:74-85.3. Aaron LA, Bradley LA, Alarcon GS, Triana-Alexander M, AlexanderRW, ... symptoms of the fibromyalgia syndrome. Although these systems are clearlyinterconnected, the review will consider separately the potential role of the hypothalamic–pituitary–adrenal (HPA)axis, the ... Chiu YH, McBeth J, Silman AJ, Ray D, Macfarlane GJ: A popula-tion based study of chronic widespread pain and the hypo-thalamic–pituitary–adrenal (HPA) axis: results from a pilotstudy [abstract]....
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Báo cáo y học: "Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: a potential tool for quantifying arthritis" pdf
... thermal imaging of the wrist and MCP, 6 normal adult wrists and hands from 3 controls wereimaged on 3 separate days. Three thermal scans wereobtained at each session and the HDI was calculated for ... new drug ther-apies, outcome measures, such as the American College of Rheumatology (ACR) 20 in RA and the ACR 30 in JIA, havebeen developed and accepted by international regulatoryagencies ... from an academic rheumatol-ogy center. Diagnosis and classification of RA or JIA weremade based on accepted ACR criteria or International LeagueAgainst Rheumatism criteria [7,8]. Active arthritis...
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Báo cáo y học: " Reduced referral and case fatality rates for severe symptomatic hyperlactataemia in a South African public sector antiretroviral programme: a retrospective observational study" pptx
... 0.002).DiscussionDespite a growing number of patients on ART at the pri-mary care clinics in the referral area of our hospital, the referral rate, severity of metabolic acidosis at presenta-tion and case fatality ... ourreferral area, and in 2008, 66.1% of adults starting ARTwere female. Female gender is a risk factor for severe SHLFigure 1 Referral rates for severe symptomatic hyperlactataemia. The referral rates ... rate ratio.Table 2: Standard bicarbonate levels and case fatality rates for severe symptomatic hyperlactataemia cases (2003-2008)Time Period Number of severe SHL casesNumber who had SHCO3...
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Báo cáo y học: "Wound contraction and macro-deformation during negative pressure therapy of sternotomy wounds" doc
... with the “ GuidefortheCareandUseofLaboratory Animals” as recommended by the U.S.National Institutes of Health and published by the National Academies Press (1996).AnesthesiaAnesthesia was induced ... and analysis,data analysis and drafting the manuscript. HE participated in the design of the study and image acquisition. HA participated in the design of the study.RI participated in the design ... University Hospital, Lund, Sweden.Authors’ contributionsCT performed the image analysis, data analysis and drafted the manuscript.MU participated in the design of the study, image acquisition and analysis,data...
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Báo cáo y học: " Pseudotumor cerebri and ciprofloxacin: a case repor" docx
... informed consent was obtained from the patient for publication of this case report and any accompany-ing images. A copy of the written consent is available for review by the Editor-in-Chief of ... insuffi-cient and are complicated by side effects. Identifying a reversible cause may potentially reverse the disease and prevent future episodes.Case presentation A 22-year-ol d African American woman ... 5(8):930-931.6. Lardizabal DV: Intracranial hypertension and levofloxacin: a case report.Headache 2009, 49(2):300-301.7. Winrow AP, Supramaniam G: Benign intracranial hypertension afterciprofloxacin administration....
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Báo cáo y học: "Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathoge"nesis of the disease potx
... SYBR Green quantitative PCR by using mRNA extracts and primers. Real-time BECLIN 1primers 5'-GGA TGG ATG TGG AGA AAG GCA AG-3'(forward primer) and 5'-TGA GGA CAC CCA AGC AAGACC-3' ... mitophagy in BMCs of FM patients.Autophagy is a regulated lysosomal pathway involved in the degradation and recycling of cytoplasmic materials [38-42]. During autophagy, cytoplasmic materials are ... microscopy studies. PB and FC participated in the design of the study and performed the statistical analysis. PB, PN, and JASAconceived of the study, participated in its design and coordination, and...
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Báo cáo y học: "Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis" pdf
... hospital admissions aswell as the length of hospitalisation (that is, total days that a patient stayed as an inpatient at the hospital as a result of the admission) per patient were provided by the ... G.Metsios@wlv.ac.uk1Department of Physical Activity, Exercise and Health, University of Wolverhampton, Gorway Road, Walsall, WS13BD, West Midlands, UKFull list of author information is available at the end of the articleMetsios ... hospitaladmissions may help focus provision of care on the indi-viduals at risk and allow targeted interventions. The mainaim of this study was to investigate whether RA diseaseactivity and disability and/ or...
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Báo cáo y học: " Innate immunity against HIV: a priority target for HIV prevention research" ppt
... proteins. In additionto having a direct impact on HIV infectivity, many of these factors also mediate innate immunomodulatoryactivity and consequently have the potential to impactinnate and ada ptive ... AIDS, NIAID, NIH (Centre for HIV and AIDS Vaccine Immunology (CHAVI) grant AI67854), and aregrateful to CHAVI colleagues, in particular Barton Haynes and AndrewMcMichael, for many stimulating ... effectorfunctionsClarify the importance of ADCVI activity as a means of antibody-mediated control of HIV infection; and Define the key characteristics of antibodies that induce strong ADCVIactivity (e.g. isotype,...
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