Báo cáo y học: " The role of the humoral immune response in the molecular evolution of the envelope C2, V3 and C3 regions in chronically HIV-2 infected patients" pdf
Báo cáo y học: " The role of the humoral immune response in the molecular evolution of the envelope C2, V3 and C3 regions in chronically HIV-2 infected patients" pdf
... C2, V3 and C3 regions along the course of HIV-2 infec-tionFigure 2Frequency, intensity and distribution of positively selected sites in the C2, V3 and C3 regions along the course of HIV-2 infection. ... the C2, V3 and C3 regions along the course of infection. The frequency and distribution of potential N-linked glycosylation sites in the C2, V3 and C3 regions are shown in each infection year. ... purposes)Frequency and distribution of potential N-glycosylation sites in the C2, V3 and C3 regions along the course of infectionFigure 3Frequency and distribution of potential N-glycosylation sites in the C2,...
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Báo cáo y học: "Respiratory allergy to Blomia tropicalis: Immune response in four syngeneic mouse strains and assessment of a low allergen-dose, short-term experimental model" pptx
... intensity and nature of the allergic responses, the genetic makeup of the host seems to play an important role in murine mod-els of respiratory allergy. On the other hand, a protocoldeveloped by ... strains using a short-term model of respiratory allergy to BtE. This study included the comparison of the allergic responses elicited by BtE with those elicited by ovalbumin in mice of the strain ... BALF The EPO activity present in BALF was determined bymeans of the colorimetric assay that was described byStrath et al. [20]. Briefly, the BALF was incubated with anerythrocyte-lysing buffer,...
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Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx
... high and constant level of c-Myc. Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc byphosphorylation of the serine 62 residue in the N-terminal of c-Myc [24]. They ... under the growth inhibitory effect of TGF1 [29-32]. The aim of the present study was therefore to reveal the role of c-Myc in mitogenic response to TGF1 in nucleus pulposuscells. The study was ... hypothesizedthat c-Myc plays a central role in TGF1 signaling for cellgrowth stimulation. Additionally, to examine the possibility of involvement of the MAPK pathway in regulation of c-Myc sta-bility, we...
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Báo cáo y học: "Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice" doc
... reported on the role of cytokines in RP,either in patients or in the corresponding animal models. In the CIA model, several cytokines have been shown to playmajor roles in the inflammatory process, ... anti-inflammatorymediators as well as proinflammatory ones. The cytokineinterleukin-10 (IL-10) has been in focus for many years in autoimmune arthritis and in other autoimmune diseases. The ... reflecting activity of the cellular as well as the humoral immune response, such as influx of cells and anti-body production. In addition, to investigate the role of inflammatory mediators in MIRP, we...
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Báo cáo y học: "A role of ygfZ in the Escherichia coli response to plumbagin challenge" pdf
... of YgfZ followed byFigure 2 Different roles played by YgfZ and SodA in counteracting plumbagin. The ΔygfZ and ΔsodA strains were transformed with pQE-sodA and pQE-ygfZ to express SodA and YgfZ, ... and the Δyg fZstrains and the parental strain were tested (Table 3).Therefore, adding a methyl group to the 3-position of naphtho quinone ring apparently diminishes the plumba-gin toxicity ... activities of different YgfZ constructs to support the growth of the ΔygfZ E. coli strain in the presence of plumbagin. Plasmids were separately transformed into the ΔygfZ strain and assayed for the diameters...
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Báo cáo y học: "Possible role of alpha-lipoic acid in the treatment of peripheral nerve injuries" ppsx
... by sub-acu te and chronic low back pain and/ or sciatica: this exerts animportant impact on the quali ty of life, causing interfer-ence of sleep and enjoyment of life.Many clinical studies ... of Physical Medicine and Rehabilitation, University of Foggia,Foggia, ItalyFull list of author information is available at the end of the articleRanieri et al. Journal of Brachial Plexus and ... 2009 of the Journal of Brachial Plexus and Peripheral Nerve Injury [1]. Wecongratulate the Jour nal for the interest in this topic.This innovative study demonstrated the protective effect of a-lipoic...
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Báo cáo y học: "A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors" ppsx
... Effect of an integrase inhibitor on the formation of HDAC4 foci in infected cells. HeLa cells we re infected with the HIV-1-basedvector in the presence and absence of the integrase inhibitor (100 ... involved in the life-cycle of HIV-1-based vectors. Our finding also supports the hypothesisthat cellular DSB repai r proteins are invo lved in PIR. At the same time, these proteins clearly have ... infected with the HIV-1-based vector and treated with the integrase inhibitor (added together with the virus), II - cells treated with the integrase inhibitoronly. Other terminology as in Fig. 2.Smith...
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Báo cáo y học: " Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus" potx
... NG-mono-methyl-L-arginine and nitronidazole both inhibited its production, suggesting a role for NO in regulating IFN-γ synthesis [17]. NO preferentially promotes IFN-γ syn the- sis and type ... evidence for increased endogenous NO synthesis, suggest ing that overproduction of NO may be important in the pathogenesis of RA. e in amed joint in RA is the predominant source of NO [45,46]. ... specifi c inhibition of iNOS by TWHF is probably responsible for the anti -in ammatory eff ects of this medicinal plant. NO treatment may lead to necrosis rather than apoptosis by decreasing intracellular...
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