... directed therapy protocol for severe sepsis and septic shock: a before and after studyMichael A Puskarich, Michael R Marchick, Jeffrey A Kline, Michael T Steuerwald and Alan E Jones Department of Emergency ... admitting physicians.Data analysis and outcomesThe primary outcome was one -year mortality rate. The admis-sion date of the index visit for sepsis was used as the baselinedate and our query was intended ... contributionsAEJ conceived the study. AEJ MAP, MRM, MTS, and JAKdesigned the study. AEJ, MAP, JAK, MRM, and MTS collectedthe data and performed the statistical analysis. AEJ drafted themanuscript and all...