... Dur-
ing assembly, the MA domain, through its myristylated
moiety and its highly basic domain, anchors assembly
complexes to membranes [4-6]. Whether assembly takes
place at the inner leaflet of the ... whether Stau1 interacts first with
NC or with the genomic RNA to recruit the other partner
or independently interacts with each of them through dif-
ferent pathw...
... to screen the clones that display the adhesion
protein, the c DNA library from N2a cells was panned
with the S protein. The 96-well plates were coated with
200 μl of the purified S protein (2 ... sequence
alignment. YL participated in the design of the NCAM siRNAs. KC
participated in the design of the study. FG and DS conceived of the study
and participated i...
... [9]. The tomato bushy stunt
virus (TBSV) protein p19 binds both siRNA and miRNA
duplexes and thus presumably inhibits the assembly of the
RISC effector complex [10]. The vaccinia virus protein ... antigen increased the recognition of SV40-
infected cells by antigen-specific cytotoxic T cells [16]. The
viral miRNA may thus reduce the susceptibility of the virus
to th...
... carried out the duplex-sonography and
participated in the radiologic diagnosis. MT. GH partici-
pated in the design of the study and performed the coor-
dination and helped to draft the manuscript. ... interests
The authors declare that they have no competing interests.
No financial support from any company was received in
the performance of this study, nor do any author...
... heavily
on functions provided by their host cells, and have
evolved diverse strategies to exploi t the biology and bio-
chemistry of hosts for their benefit [1]. The ubiquitin
system is one of the ... degraded
by the lysosome pathway and in part by the proteasome
pathway in HSV-2-infected cells. The decrease of Itch in
Vero-GFP-UL56 cells was also blocked by CQ and par-...
... (measured at entry)
achieved during DSG treatment,
no further increase of >25% in
the maximum urinary protein
excretion within the previous
two cycles
Within the previous two cycles, a
further increase ... treatment
additional urinary protein
excretion
1
decreased by < 25%
during DSG treatment; no further
increase of >25% in the
maximum urinary protein
excretion within...
... not included in the study,
creating a bias against the treatment. On the other hand
some patients could be compliant with the bundle just
because their severity was low and they did not need flu-
ids ... should really be to complete the whole
bundle gaining the synergy of the bundle elements per-
formed in unison rather than each one independently.
Only 12% of our patients f...
... complex assembly and
enzyme catalysis in vivo.
Membrane affinity of a Gla protein often correlates
with its membrane localized activity. Strategies used to
increase the affinity of the Gla protein membrane
interaction ... Ca
2+
turns the N-terminal part of the Gla
domain inside out, exposing the hydrophobic x-loop
to solvent and burying the majority of the Gla resi-
d...
... ster-
oids, or other agents that may affect the outcomes of the
study other than the rescue medication. Any medication
taken by subjects for two months prior to the inclusion of
the study, and whose ... mg/day
Copper 0.074 mg/day 0.11 mg/day
Iron 119 mg/day 178 mg/day
Lead 0.013 mg/day 0.020 mg/day
Lithium 0.02 mg/day 0.03 mg/day
Magnesium 11 mg/day 17 mg/day
Manganese 0.29 mg/day...
... disease, a type II hypersensitivity reac-
tion is present with antibody and T-lymphocyte reactivity
to the NC1 domain of the alpha3 chain of type 4 collagen
[1]. These specific antigens exist on the ... pathogenic antibodies with plasmapher-
esis, as the activity of the disease correlates with the anti-
body level. The latter has drastically improved the
prognosis and...