Báo cáo khoa học: " Etomidate, sepsis, and adrenal function: not as bad as we thought" docx
Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx
... Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells Seyed A. Mousavi1, Knut E. Berge1, Trond Berg2 and Trond ... low-density lipoprotein receptor; LPDS, lipoprotein- depleted serum; PCSK9, proprotein convertase subtilisin ⁄ kexin type 9; PCSK9-WT, wild -type proprotein convertase subtilisin ⁄ kexin type 9; TC, ... characteristics of binding of PCSK9 to LDLR. Using PCSK9 iodinated by the tyraminecellobiose (TC) method ([125I]TC-PCSK9), we measured the affinity and kinetics of binding of PCSK9 to LDLR on HepG2 cells...
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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf
... pore formation by the T3SSFEBS Journal 278 (2011) 414426 ê 2010 The Authors Journal compilation ê 2010 FEBS 421 REVIEW ARTICLE Membrane targeting and pore formation by the type III secretion system ... release their cognate chaperones and are injected through the translocon pore and into the targetcytoplasm. IM, inner membrane; MO, outer membrane. P J. Matteăet al. Membrane targeting and pore formation ... al. Membrane targeting and pore formation by the T3SSFEBS Journal 278 (2011) 414426 ê 2010 The Authors Journal compilation ê 2010 FEBS 419 V antigen protects against type III intoxication and lung...
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... The Authors Journal compilation ê 2009 FEBS 135 Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio ... proteins, a leucine zipper domain and a C2H2 zinc finger domain, both of which arethought to help mediate DNA binding and may be involved in the induction of dimerization [43]. Each of these ... protein–protein interactions, aSTAT protein DNA-binding domain and an SH2domain, which binds phosphorylated tyrosine residues in the context of a longer peptide motif within a targetprotein [38,39]. Within...
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Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... (0.08) 14 86 (780) 10 08 (19 ) Helix III (4 3–5 2) 0.87 (0.06) 18 85 ( 710 ) 15 96 ( 51) Helix III (5 3–5 9) 0.82 (0.09) 10 30 ( 613 ) 905 ( 21) Helix III (4 2–5 6) 0.87 (0.06) 16 30 (809) 12 97 (37) Helix III ( 51 56) ... 2007 FEBS Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain hints from 15 N-NMR relaxation studies Devrim Guămral, Luana Nadalin, Alessandra Corazza, ... of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1 H-NMR spectroscopy and restrained molecular mechanics. Eur J Biochem2 41, 10 1 11 3.5 Guazzi S, Price M,...
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Tài liệu Báo cáo khoa học: Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori docx
... 2006 The Authors Journal compilation ê 2006 FEBS Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori Cong Han1, Lirui Wang1, Kunqian Yu1, ... enco-ding SDH from H. pylori strain SS1. The recombinantH. pylori shikimate dehydrogenase (HpSDH) wascloned, expressed, and purified in E. coli system, and its biochemical and enzymatic characterizations ... expressed, and purified in Escherichia coli system. The enzymatic characterization of HpSDH demonstrates its activity with kcat of 7.7 s)1 and Km of 0.148 mmtoward shikimate, kcat of 7.1 s)1and...
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Tài liệu Báo cáo khoa học: "Exploiting Syntactic and Shallow Semantic Kernels for Question/Answer Classification" docx
... Republic, June 2007.c2007 Association for Computational LinguisticsExploiting Syntactic and Shallow Semantic Kernels for Question/Answer ClassificationAlessandro MoschittiUniversity of Trento38050 ... Efficient convolution kernels for depen-dency and constituent syntactic trees. In ECML’06.S. Quarteroni and S. Manandhar. 2006. User modelling for Adaptive Question Answering and Information Retrieval. ... introduces a viable ap-proach based on tree kernels. 3 Syntactic and Semantic Kernels for TextAs mentioned above, encoding syntactic/ semantic information represented by means of tree structuresin...
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Tài liệu Báo cáo khoa học: "Balancing Clarity and Efficiency in Typed Feature Logic through Delaying" docx
... Deliverable.D. Flickinger. 2000. On building a more efficient Balancing Clarity and Efficiency in Typed Feature Logic through DelayingGerald PennUniversity of Toronto10 King’s College Rd.Toronto ... degrees of instantiation in LTFS,however, corresponding to long subtyping chainsthat terminate in ⊥. A more general and usefulprimitive in a typed language with such chains issuspending until ... the inten-tion of minimizing this extra cost (indeed, the ERGbaseline had not yet been devised).2 Modularity: the cost in clarity Semantic types and inheritance serve to organizethe constraints...
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Báo cáo khoa học: Conformational stability and multistate unfolding of poly(A)-specific ribonuclease docx
... structure and stability of poly(A)-specific ribonuclease. Arch Biochem Biophys461, 255–262.18 Liu W-F, Zhang A, He G-J & Yan Y-B (2007) TheR3H domain stabilizes poly(A)-specific ribonuclease ... Allosteric regulation of human poly(A)-specific ribonuclease by cap and potassium ions. Biochem Bio-phys Res Commun 379, 341–345.24 Jaenicke R (1999) Stability and folding of domain pro-teins. ... importance of being dimeric. FEBS J 272,16–27.36 Pace CN, Laurents DV & Thomson JA (1990) pHdependence of the urea and guanidine hydrochloridedenaturation of ribonuclease A and ribonuclease...
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Báo cáo toán học: " Mesh patterns and the expansion of permutation statistics as sums of permutation patterns" docx
... 4 Mesh patterns and the expansion of permutation statistics as sums of permutation patterns Pett er BrăandenDepartment of Mathematics, Stockholm University,SE-106 91 Stockholm, SwedenAnders ... permutation of the first kind if and only if L and R are Andr´epermutations of the first kind.Theorem 7. Let π ∈ Sn. Then π is an Andr´e permutation of the first kind if and onlyif it avoidsandr´e ... characterized the permutations sortable by two passes through a stack as thosethat avoid the classical pattern 2 341 and the barred pattern 3¯5241. So, in terms of mesh patterns, it is the set of permutations...
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Báo cáo khoa học: "Endotracheal tubes and imposed work of breathing: what should we do about it, if anything" pps
... Bransonventilation. Recent work suggests that the work of breathingpostextubation may actually increase compared with work of breathing through the ET tube, raising questions about theconclusion of the study ... advantages of ATC over PSV are reduced work of breathing as patient demand varies, preservation of anormal, variable breathing pattern, and improved synchrony. Ina recent trial of spontaneous ... Maeda and coworkers is the role of expiratory compensation. One distinct difference in theoperation of the Drager Evita 4 and Puritan Bennett 840 isthat Evita 4 provides both inspiratory and...
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Báo cáo khoa học: "Human endotoxemia and human sepsis: limits to the mode" ppt
... observed by van Eijk and co-workers, suggesting that, despite the seemingly adequateCommentary Human endotoxemia and human sepsis: limits to the modelRamon Anel1 and Anand Kumar21Assistant ... hematologic and cardiovascular septicresponses in septic shock, the ability to mimic other aspects of human sepsis is open to question. The current study demonstratesthat human experimental endotoxemia ... Nosuch human model can mimic all of the critical elementspresent in spontaneous human sepsis.In this issue, van Eijk and colleagues [15] test the utility ofthis model of human endotoxemia in the...
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Báo cáo khoa học: "A CC and CXC chemokine levels in children with meningococcal sepsis accurately predict mortality and disease severity" pptx
... in menin-gococcal disease. ConclusionSerum levels of CXC and CC chemokines in children in the ini-tial phase of meningococcal sepsis can predict disease sever-ity and outcome.Competing interestsThe ... microbial induced pro-Key messagesã Extremely high levels of CC chemokines as well as CXC chemokines are found in sera from children in the initial phase of meningococcal sepsis. ã Chemokine levels ... the serum levels of CXC and CC chemokines during the initial phase of meningococcal sepsis in children and to determine their relationship with dis-ease severity and outcome.Materials and methodsPatientsChildren...
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Báo cáo khoa học: "Etomidate, pharmacological adrenalectomy and the critically ill: a matter of vital importance" pps
... translates into a numberneeded to treat of five patients. The early advantage of relative haemodynamic stability at intubation, which itself isnot an important patient-centred outcome and can ... these patients are treated with cortico-steroids [9]. Other critically ill patients without septic shockmay also be at risk but the data are observational and weaker[8]. There can be a lag time ... for steroid replace-ment may be variable and is as yet undefined.It would therefore seem reasonable for ICU physicians tofollow the advice of Annane and avoid the use of etomidate[12]. This...
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Báo cáo khoa học: "Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock" docx
... A includes patients with severe left heart failure without additional severe sepsis/ septic shock, and group B includes patients with severe left heart failure with additional severe sepsis/ septic ... A includes patients with severe left heart failure without additional severe sepsis/ septic shock, and group B includes patients with severe left heart failure with additional severe sepsis/ septic ... A includes patients with severe left heart failure without additional severe sepsis/ septic shock, and group B includes patients with severe left heart failure with additional severe sepsis/ septic...
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Báo cáo khoa học: " Etomidate, sepsis, and adrenal function: not as bad as we thought" docx
... respiratorycompromise, and commonly both. The institution ofmechanical ventilation is a necessary therapy in most of thesepatients and should be performed as safely, and quickly, as possible. The ... relatively experienced hands and in a setting (interms of both location and anesthesia equipment and personnel) that is best for the patient [9]. The use of otherinduction agents, such as propofol or ... shock, and providing an environment in which theoperator can place an endotracheal tube as efficiently as possible with avoidance of further significant hemodynamic orrespiratory compromise is not...
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