... 3B). Thus for the SBD tree there is not anobvious border between the hydrolases and transglycosi-dases, but rather there may be one between the compactcluster of Bacillus and Thermoanaerobacter ... likely to be necessary in the four-domain proteins to connect domain C to the SBD.Possible linker sequences for the a-amylases and malto-tetrao- and maltopentao-hydrolases are shown in Fig. 2A.These ... This work, taken together with theresults of the presentstudy, as well as with many theoretical and experimentalresults on sequence and structure similarities betweenamylases and CGTases [19,20,22,26,30,94,116–118],...