... ↔Cell death ↔↔↔↔Collagen synthesis ↑↑↑ Type I ↓ Type II ↔ Type I ↔ Type II ↔ Type I ↔ Type II ↓↓↓ Type I ↓ Type IISerum GlucoseAlginate With Without With WithoutCell proliferation ↓↓ ↓↓↓ ... deprivation, but not serum or oxygen deprivation,inhibited synthesis of type I and type II collagen, both in monolayer and alginate cultures.Conclusion This study demonstrates that factors present ... ↔↑↑↔↔Cell death ↔↓↓↔↔Collagen synthesis ↓ Type I ↑↑ Type II ↔ Type I ↔ Type II ↔ Type I ↔ Type II ↔ Type I ↓↓ Type II↑, increased; ↓, decreased; ↔, no change (from control conditions).Arthritis Research...