Báo cáo y học: "b-TrCP is dispensable for Vpu’s ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release" pot
Báo cáo y học: "b-TrCP is dispensable for Vpu’s ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release" pot
... Retrovirology 2011, 8:9http://www.retrovirology.com/content/8/1/9Page 8 of 15RESEARCH Open Accessb-TrCP is dispensable for Vpu’s ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 releaseHanna-Mari ... bars), even thoughthey displayed slightly increased steady-state levels rela-tive to Vpu wt due to their higher stability [29]. Parallelanalysis for expression of CD4 revealed the expected[19] ... Infectious HIV-1 ( % Control)101100 HIV-1 wt HIV-1 YSXsi Controlsi ȕ7U&3si ȕ7U&3 HIV-1 YSX HIV-1 wtsi ȕ7U&3 si ȕ7U&3si Control HIV-1 YSX HIV-1 wt HIV-1 YSX HIV-1 wtB HIV-1 YSXHIV-1...
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Báo cáo y học: " CXCR2 is critical for dsRNA-induced lung injury: relevance to viral lung infection" pps
... of lung edema; microvascular permeability; mRNA;ELISA analysis; and histopathological and immunohisto-chemical analysis by fixing in 4% paraformaldehyde at 25 to 30 cm H2O pressure and embedding ... for 15 min. The cell-free supernatantswere assayed by specific ELISAs and collected cells wereanalyzed for total cell counts and cytospin differentials.Lung tissue was then processed for the ... airway reactiv-ity and are hallmarked by the recruitment ofinflammatory cells with resultant changes to the airwayepithelial cell lining. Inflammation can also extend fur-ther into the lung to...
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Báo cáo y học: "A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets" pptx
... [11,17,21-23]. The large number of possible histone modificationshas led to the ‘ histone code’ hypothesis, which statesthat combinations of different histone modifications spe-cify distinct chromatin ... examine the combina-torial effects of chromatin feature s, a nd investigate to what extent the histone code hypothesis is valid. Byapplying the chromatin-based model to predict the expression of ... designed the study. CC and KKY performed the full analysis. CC, KKY, KYY, RA, JR, CS and MG wrote the manuscript.Received: 21 December 2010 Revised: 26 January 2011Accepted: 16 February 2011 Published:...
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báo cáo khoa học: " Lutein is needed for efficient chlorophyll triplet quenching in the major LHCII antenna complex of higher plants and effective photoprotection in vivo under strong light" pps
... oxygen species produced during oxygenic photo-synthesis [3]. Also, the energy level of the S1 state of dif-ferent xanthophylls, which is critical for energy transferfrom chlorophyll, is very ... and the structural basis ofregulation of photosynthesis by protein phosphorylation.Physiol Plant 1997, 100:863-868.41. Allen JF: How does protein phosphorylation regulate photo-synthesis? ... to migrate from grana to stroma membranes [39] or animpaired capacity for LHCII phosphorylation in the mutant. The first hypothesis is ruled out by the results ofProposed role of xanthophylls in higher...
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Báo cáo y học: "VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-κB signaling pathway" pot
... by the proteosome [24]. Following the degradation of IκB,NF-κB is released and is free to translocate to the nucleusand to activate its cognate genes. A key regulatory step inthis pathway is ... phosphorylates the inhibitor of NF-κB, IκB(IκBα as the dominant form in majority of cells). The phosphorylated IκBα is then degraded by the proteasomeand releases bound NF-κB into the nucleus, ... andpathogenesis and certainly warrant further study.Up to now, the organization of regulatory elementsrequired for the expression of VEGF and Flk-1 has onlybeen partially defined [15,17]. Several cis-acting...
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Báo cáo y học: "Are acupoints specific for diseases? A systematic review of the randomized controlled trials with sham acupuncture controls" pps
... and frequency) and primary outcome.Risk of bias assessment The Cochrane Collaboration’s tool for assessing risk ofbias was used to evaluate the risk of bias of the follow-ing key aspects: sequence ... specific for others such as fibromyalgia [22,32,33]. The peripheral and central sensitization in the patientswith fibromyalgia syndrome may explain the nonspecifi-city of acupoints. However, due to ... treatment frequency and total numberof treatment sessions [13,31]. The acupuncturist’spro-fessional ability is also an important factor. In the included trials, information about the acupuncture...
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Báo cáo y học: "Are acupoints specific for diseases? A systematic review of the randomized controlled trials with sham acupuncture controls" pdf
... of the herb HS acting on the brain can serve as apotential therapy for the Alzheimer ’sdisease.Inthiscase, HS targets the brain (WM) instead of the Shen(kidney).These language gaps limit the ... biomedical ontologies. These ontolo-gies are relevant to CM research especially when relat-ing CM to WM. In addition, efforts have begun to create new ontologies specifically for CM. For example,China ... at the semantic l ayer (built using the Semantic Web technology) and then be mapped to the local queries against the underlying relational databases.DartGrid [18] is a system demonstrating the...
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Báo cáo y học: "Non-invasive ventilation for critically ill patients with pandemic H1N1 2009 influenza A virus infection" pot
... necessarily change the natural disease course. On the other hand, NIV may increase the risk of respiratory pathogen transmission [2] and there is not enough evidence to support the treatment ... complicated by pneumonia, acute lung injury (ALI) or acute respira-tory distress syndrome (ARDS) because although NIV temporarily improves oxygenation and reduces the work of breathing in these patients, ... Instituto Nacional de Cancerología and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoFull list of author information is available at the end of the articleAuthors’...
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Báo cáo hóa học: " EXISTENCE OF ZEROS FOR OPERATORS TAKING THEIR VALUES IN THE DUAL OF A BANACH SPACE" potx
... (·, y) iscontinuousforally ∈ B1,wethenrealize that the restriction of f to X0× B1satisfies the hypotheses of Theorem 3, B1beingconsidered with the relativization of the strong topology. ... metric. In practice, the most usual choice of τ is either the strong topology or the weak topology provided E is also separable. The aim of this short paper is to establish the following result ... continuous operator from the strong to the weak topology. Assume that the s et C ={x ∈Br: A(x),x≥0} is disconnected and that, for each x, y ∈ Br\ C, A(x), y < 0.Then, there exists x∗∈...
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Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx
... inhibitory effect ofTGF1 [29-32]. The aim of the present study was therefore to reveal the roleof c-Myc in mitogenic response to TGF1 in nucleus pulposuscells. The study was designed to (1) ... morphologically uniformsince primary culture, the second passage was used for the experiments. With regard to keratinocytes, they will not prolif-erate if keratinization is triggered by passage. Therefore, ... reported that the instability of oncoprotein Myc is important to avoid its accumulation in normal cells and thatMyc is destroyed by ubiquitin-mediated proteolysis [52]. In thisstudy, we showed...
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