Báo cáo y học: "The mouse “xenotropic” gammaretroviruses and their XPR1 receptor" pps
Báo cáo y học: "The mouse “xenotropic” gammaretroviruses and their XPR1 receptor" pps
... arry at least 5 func-tionally distinct XPR1 variants [13-15,78, 95,96,101].These five Mus XPR1 s differ in their ability to supportentry by prototype X-MLVs and P-MLVs and by thetwo wild mouse ... APOBEC and tetherin/BST2 are broadly antiviral, whereas Fv1targets only MLVs, while XPR1, LVIF, and the RMCF-like interference genes restrict only X/P-MLVs. Xpr1 receptor polymorphism and glycosylation ... secondMLV type with a distinctly different host range was sub-sequentlyisolatedbyLevyandPincusfromtheNZBmousestrain[2].Thesevirusesweredefinedbytheirapparent inability to infect cells of their...
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Báo cáo Y học: The Fe-only nitrogenase and the Mo nitrogenase from Rhodobacter capsulatus A comparative study on the redox properties of the metal clusters present in the dinitrogenase components doc
... G. (1953) Diphosphofructose-aldolase, Phosph oglyceraldehyd-deh ydrogenase, Milchsa¨ure-dehydrogenase, Glycerophosphat-dehydrogenase and P yruvat-kinase aus Kaninchenmuskulatur in einem Arbeitsgang. ... doubtsprimarily arose due to the fact t hat preparations of the typeof anf-dependent nitrogenase were, regardless of their origin,generally characterized by either extremely l ow catalyticactivity [5,6,9,18] ... indeed be isolated and purified as intact and catalytically active proteins, and (b) that the FeFe protein definitely does not contain a niron–molybdenum cofactor (FeMoco), but a clearly well-functioning...
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Báo cáo Y học: The evolution of monomeric and oligomeric bc-type crystallins potx
... dimericprototypes for the respective families of c-andb-crystallins,andsimplyreferredtoasc-type or b-type crystallins,respectively.Both monomeric c-type crystallin and the subunit ofdimeric b-type crystallin ... monomeric c-type and oligomericb-type crystallins has been described and analyzed in evo-lutionary terms. Data and hypotheses from molecular gen-etics and structural investigations converge and suggest ... extensions, they are mostly flexible and mobile [58] and do not seem to play any roles in folding and domain association [44,59,60]. The proximal stretch ofTable 1. Alignment of c- and b-type crystallins....
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Báo cáo y học: "The Changing Microbial Environment and Chronic Inflammatory Disorders" doc
... immuno-regulatory and anti-inflammatory properties and becauseit enhances clearance of amyloid-b.54Depression and AnxietySome stress-related psychiatric conditions, particularlydepression and anxiety, ... secondary to dietarychanges will play a role, and obesity itself increasesinflammatory cytokine levels. Similarly, urbanization led toincreased incidences of diseases such as tuberculosis, and selection ... saprophytic mycobacteria, otheractinomycetes, and, no doubt, many other genera.Second, helminthic infections, always present in humans’progenitors but possibly increased in variety and loadwhen...
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Báo cáo y học: "The anti-vaccination movement and resistance to allergen-immunotherapy: a guide for clinical allergists" ppt
... likely had thimerosal init. By weight thimerosal is 40.7% mercury. Mercury isaneurotoxinandcanaffectmanyareasofyourbody.”Another blog entry [71] from the website, http://child-healthsafety.wordpress.com, ... history Over a century Nearly a centuryTherapeutics contains adjuvants and preservatives? Yes, often Yes, oftenSynonyms: Medical and lay-public vernacular a) shots a) allergy shotsb) vaccines b)allergen ... websites of the CanadianSociety of Allergy and Clini cal Immunology [74], or theAmerican Academy of Allergy, Asthma and Immunol-ogy [75]). Yet, while the Internet is a widely used publicsource of...
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Báo cáo y học: "The clinical-familial correlates and naturalistic outcome of panic-disorder-agoraphobia with and without lifetime bipolar II comorbidity" potx
... clomipramine and 10 mg of paroxetine. Dosage wasgradually increased (10 mg every 2 days for TCAs and 5mg every 4 days for paroxetine) to a maximum of 300 mg and 40–50 mg respectively. The treating ... with panicdisorder. Can J Psychiatry 1994, 39:91-94.24. Freeman MP, Freeman SA, McElroy SL: The comorbidity of bipo-lar and anxiety disorders: prevalence, psychology and treat-ment issues. J ... comorbidity in bipolar disorderwith psychotic features. Br J Psychiatry 1999, 175:467-471.27. Strakowsky SM, Keck PE Jr, McElroy SL, Loczac HS, West SA: Chro-nology of comorbid and principal syndromes...
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Báo cáo y học: "The importance of measuring psychosocial functioning in schizophrenia" pps
... General Psychiatry2011 10:18.Brissos et al. Annals of General Psychiatry 2011, 10:18http://www.annals-general-psychiatry.com/content/10/1/18Page 7 of 7reliability and construct validity and captures ... schizophrenia, and may be to some extent independent of other symp-toms [21]. They may precede the onset of illness,becoming more pronounced in the prodrome and earlyyears following diagnosis, and then ... PsychiatricHospitalar Centre, Lisbon, Portugal.3Social Psychiatry Group, OxfordUniversity Department of Psychiatry, Oxford, UK.4Santa Maria’s UniversityHospital, Department of Psychiatry,...
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Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt
... characterized as oxygenasesgoverned by oxygen, 2-oxoglutarate (2-OG), iron (Fe2+) and ascorbic acid (collectively termed HIF prolyl hydroxylasedomain [PHD]-containing enzymes), and factor inhibiting ... namely NF-κB and HIF.Mimicking hypoxia by treatment of cells with small interferingRNA against PHD-1 or PHD-2 or the pan-hydroxylaseinhibitor dimethyloxalylglycine (a 2-OG analogue, and aninhibitor ... played by HIF-1α.The aforementioned studies indicate that HIF-1α and HIF-2αplay different roles. However, some findings imply that theyplay completely opposing roles. In their 2005 study,...
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Báo cáo y học: "The relationship between cancer and rheumatoid arthritis: still a large research agenda" ppsx
... learn to subtype RA, it would be important to look at therelationship between anti-cyclic citrullinated peptide antibodystatus and malignancy. Is the risk of lymphoma primarily seen incertain ... possibility is suggested byresults of the APPROVE trial, which showed rofecoxibreduces the recurrence of adenomatous polyps as well as therisk of advanced adenomas at one and three years afterrandomization ... of malignancy in RAforward but raises many important questions for futureresearch. First, as much of the literature they cite (and most ofthe patients included in the meta-analysis) is from...
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Báo cáo y học: "The relationship between inflammation and new bone formation in patients with ankylosing spondylitis" docx
... Similarly, for assessment and quantification of inflamma-tory spinal changes, the AS-spinal-MRI scoring system [13]has shown good discriminatory capacity, validity, and sensitiv-ity to change ... inhibited by TNFblockers.Figure 1Formation of new syndesmophytes in the upper and lower edges of L1/L2 and L2/L3Formation of new syndesmophytes in the upper and lower edges of L1/L2 and L2/L3. ... magneticresonance imaging and new bone formation as identified byconventional radiographs are characteristic of ankylosingspondylitis. Whether and how spondylitis and syndesmophyteformation are linked...
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