Báo cáo y học: " Morbidity and cost burden of methicillin-resistant Staphylococcus aureus in early onset ventilator-associated pneumonia" potx

... the findings of this and other studies suggest that any costs associated with theimplementation of such measures may quickly be offset by cost savings in the ICU [25,26]. Any therapeutic interventiondirected ... were only able to identify early onset VAP (mostly within five days of hospitalization).Study sampleDuring the study period, a total of 59 US hospitals (16 teach-ing and 43 nonteaching) collected ... online http://ccforum.com/content/10/3/R97Page 1 of 7(page number not for citation purposes)Vol 10 No 3Research Morbidity and cost burden of methicillin-resistant Staphylococcus aureus in early...

Báo cáo y học: "Serological and molecular expression of Hepatitis B infection in patients with chronic Hepatitis C from Tunisia, North Africa" pdf

... the type of interaction may depend on th e chronol-ogy of contamination with the two viruses: HCV super-infection in previously HBV infected patients, co-infec-tion or HBV infection in HCV ... HCV infection, as defined bypersistent positivity of HCV serology and RNA for aminimum of 6 months. They were followed for theiranti-HCV positivity in diff erent hepato-ga stroenterologydepartments ... analysis and in drafting and discussing the manuscript. SBH and AS carried out themolecular tests and participated in data NM, IC, MA and NBM contributedto identification of the patients included...

Báo cáo y học: "Phenotypical and functional characterization of alveolar macrophage subpopulations in the lungs of NO2-exposed rats" pot

... pri-mary antibodies were detected using a biotin-PE/streptavidin-anti-streptavidin enhancing system and labeling of AM was analyzed by flow cytometry following gating by help of for-ward and ... alternativelyactivated phenotype, mainly characterized by a reducedexpression of the proinflammatory cytokines TNF-α and IL-1β and a significantly increased expression and produc-tion of the antiinflammatory ... proinflammatory cytokine TNF-α. However, signifi-cantly increased mRNA levels were found in the ED7+population for IL-12 p40 and iNOS. Interestingly, theexpression of the antiinflammatory cytokine...

Báo cáo y học: "Regulation and prognostic relevance of serum ghrelin concentrations in critical illness and seps" ppsx

... physiologically growth hormone(GH) secretion independent of hypothalamic GH-releas-ing hormone and causes weight gain and obesity byincreasing food intake and diminishing lipid utilisation in non-critically ... isderived from the stomach and nearly all of the remainingone third from the small intestine [5,6]. Rat ghrelin is verysimilar to human ghrelin and differs only by two aminoacids [7]. Therefore ... but possibly blood glucose and insulin mayparticipate in regulation [24]. However, we found a closeinverse correlation of ghrelin with serum glucose and insulin only in the subgroup of non-sepsis...

Báo cáo y học: "Identification and functional characterization of cis-regulatory elements in the apicomplexan parasite Toxoplasma gond" pptx

... Biology 2009, 10:R34involved in glycolysis presents an intriguing case study fromdevelopmental, evolutionary and regulatory perspectives.We analyzed the upstream sequences of 11 genes involved in tachyzoite ... are needed to fully resolve these intriguingresults.Genes involved in nucleotide biosynthesis and salvagePurines and pyrimidines are the building blocks of nucleicacids in living cells. All ... destroyingthe original sequence of the candidate motif but maintainingthe spacing within the promoter (Figures 1c, 2c, 3c and 4c).Successful mutagenesis was confirmed by sequencing or byrestriction...

Báo cáo y học: "Retroperitoneal packing as part of damage control surgery in a Danish trauma centre – fast, effective, and cost-effective" pot

... noliving humans were involved in the study. Apart frompacking swabs in the abdomen and removing them again,the procedure did not differ from an ordinary autopsy.The sessions were directed by ... was having all involved doctorstrained within six months. We evaluated the course byasking the doctors about their approach to deciding on and performing retroperitoneal packing. Finally, we ... procedure, and trauma audits show that many hesitate to perform the procedure, indicating aneed for hands-on training for this simple and potentially lifesaving procedure.Materials and methods: During...

Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"

... pharmacy data. While clinical disease activity measures remain the gold standard for assessing effectiveness in RA, the many large administrative data sources in the U.S. and internationally are ... written informed consent. VARA contains demographic, clinical and RA-specific information including disease activity scores (DAS), as assessed by physicians using the DAS28 [23] and the Clinical ... data for a number of rheumatology conditions including diagnoses for RA, spondyloarthropathies, systemic lupus erythematosus, fibromyalgia, osteoarthritis, joint injection, and joint replacement...

Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta

... cascade of cytokines and chemokines necessary for tissue eosinophilia without involvement of draining lymphoid tissues. We studied the induction of lung allergic in- flammation in mice lacking ... the last intranasal challenge. Briefly, mice were maintained inside a whole-body plethysmograph (Buxco, Troy, NY) capable of meas-uring changes in airflow and trans-thoracic pressures and resistances ... the cytokines IL-4 and IL-13, which in turn induced epithelial production of the eosinophil chemokine eotaxin [28]. Since local Th2 cell produc-tion of cytokines has also been implicated in...

Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx

... hydrophobicity (pandinin 1–0.1214,opistoporin 1–0.1652) and the hydrophobic moment, whichis nearly double for pandinin 1 (pandinin 1 0.1071,opistoporin 1 0.055). The amino acid substitutions highlyresponsible ... pandinin 1 contains only one charged aminoacid in this fragment. Parameters that might in uenceantibacterial activity that differ between opistoporin 1 and pandinin 1 are the hydrophobicity ... recently described in the venom of spiders and insects.Parabutoporin and opistoporin 1 were synthesizedchemically and preliminary studies on antibacterial activityshowed that the quality and...

Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf

... full-length proteins.Keywords: calretinin; calcium; calbindin D28k; EF-hand;NMR secondary structure.Calretinin (CR) and calbindin D28k(Calb) are homologouscalcium-binding EF-hand proteins with ... (B)45Ca-overlay of the blot shown in part A indicating that CR and GSTfusion products of CR fragments bind45Ca.Fig. 6. ‘Glycine 6’ of the calcium-binding loopis a sensitive indicator of calcium loading. ... Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland;2Department of Biochemistry and Molecular Biology, University of Debrecen, Hungary;3Department of Inorganic...

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