Báo cáo y học: "Combination therapy versus monotherapy: a randomised pilot study on the evolution of inflammatory parameters after ventilator associated pneumonia [ISRCTN31976779]" pot

... 2ResearchCombination therapy versus monotherapy: a randomised pilot study on the evolution of inflammatory parameters after ventilator associated pneumonia [ISRCTN31976779]Pierre Damas, Christophe Garweg, ... inflammatory parameters and duration of ventilatory support, and mortality as a secondary outcome. The a priori hypothesis is that synergistic action of combination therapy will accelerate the ... receiving antibiotics, among others. If this study failedto demonstrate any advantage of combination therapy overmonotherapy, the use of empirical combination therapy remains probably relevant in patients...

Báo cáo y học: "Candida albicans genome sequence: a platform for genomics in the absence of genetics" potx

... from the genome sequences of a pathogen such as C. albicans (and from other related fungi)?C. albicans has rarely been isolated in nature away from ananimal host and has probably co-evolved along ... infection by Margarita Silva-Hutner at the Department of Dermatology, ColumbiaCollege of Physicians and Surgeons (New York, USA). The original isolate number was 1775 and the strain is identicalwith ... locusin the asexual pathogenic yeast Candida albicans. Science1999, 285:1271-1275.10. Hull CM, Raisner RM, Johnson AD: Evidence for mating of the ‘’asexual’’ yeast Candida albicans in a mammalian...

Báo cáo y học: " Electroconvulsive therapy-induced mania: a case report" pps

... episodes was achieved by resumption of psy-chiatric medication.DiscussionElectroconvulsive therapy is generally used on severelydepressed patients when other forms of therapy, such asmedications ... normal. Treatment withhaloperidol, 30 mg/day, biperiden, 4 mg/day, anddiazepam, 10 mg/day, was not satisfactory. The patienthad total of five ECTs, but was discharged from the hospi-tal against ... [8-10]. The neuroendocrine the- ory hypothesizes that the seizure causes the hypothala-mus to release chemicals that cause changes throughout the body [9].ECT affects the brain by increasing metabolism...

Báo cáo y học: "Cord blood versus age 5 mononuclear cell proliferation on IgE and asthma" ppt

... biological data (n= 359).Parental report of symptoms assessed by:1 Study Questionnaire,2BriefRespiratoryQuestionnaire, and3ISAAC Eczema Module.ISAAC, International Study of Asthma and Allergy ... coordination. RLM conceived of the study, and participated in its design and coordination and statistical analysis andhelped to draft the manuscript. All authors read and approved the finalmanuscript.AcnowledgementsFunding ... age 5, parental report of eczema was determined using the validated InternationalStudyofAsthmaandAllergyinChildhood(ISAAC)eczema questionnaire [23-25], and parental report of asthma was determined...

Báo cáo y học: " Pregnancy and delivery while receiving vagus nerve stimulation for the treatment of major depression: a case report" pot

... informedconsent. The case study patient, a Caucasian woman aged 28 yearswith a DSM-IV diagnosis of unipolar depression, wasenrolled in the acute and long-term phases of the pilot study of VNS therapy ... after the initiation of VNS therapyFigure 2 The patient's score on the CGI-S scale also indicated a substantial improvement after the initiation of VNS therapy. Pregnancy from May 30, 2002 ... therapy, as indicated by HRSD28 and MADRS scores. VNS therapy was initiated on March 17, 1999. The patient reported her pregnancy on May 30, 2002, and delivered a healthy child on January...

Báo cáo y học: "Collaboration between general hospitals and community health services in the care of suicide attempters in Norway: a longitudinal study" ppt

... information about after- care providers in the CHS.Data on the number of inhabitants in each municipalityand the degree of urbanisation of the municipality (rural,rural/urban or urban) were gathered ... structural elements as indicators of a chain of care model is one way of managing the considerable het-erogeneity in population size, population density andorganisation and content of the services ... EM and EAF participatedin the acquisition of data. All authors participated in the interpretation of data,revised it critically for important intellectual content and have read andapproved the...

Báo cáo y học: "Correction: What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis - the first 50 years" docx

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Báo cáo y học: "Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells" ppsx

... unlikely that CIA pathogenesis can bereduced to mediation by anti-CII antibodies alone. The question is whether autoreactive T cells might have anadditional role in CIA, in particular whether they ... wasscored as 1, with a maximum of 10 per paw, and an arthriticankle or mid-paw was given a score of 5.StatisticsArthritis incidence and severity were analysed by χ2 analy-sis and the Mann–Whitney ... this study. Monoclonal antibodies were generated as culture superna-tants and purified by affinity chromatography with γ-bindplus affinity gel matrix (Pharmacia, Uppsala, Sweden). The IgG content...

Báo cáo y học: "Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on" pps

... signaling pathwaysActivation of JAK kinases and subsequent stimulation of transcriptional activity of the STAT family of transcriptionfactors is one of the main signaling pathways triggered bycytokines. ... on DNA binding capacity,transcriptional activity and gene target specificity.Acetylation in human immune-mediated inflammatory disease The most detailed analyses of how alterations in HAT andHDAC ... tools in the treatment of many chronic inflammatory diseases, includingasthma and RA. Recent findings in the study of inflammatory lung diseases demonstrate that HAT activity and HDACactivity significantly...

Báo cáo y học: "Correction: What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis - the first 50 years" pps

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