Báo cáo y học: " Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization" potx
Báo cáo y học: " Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization" potx
... purposes)RetrovirologyOpen AccessResearch Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerizationMohammad A Khan, Ritu Goila-Gaur, Sandra ... between encapsidation, lipid raft association, and genomic RNA binding of A3G. Surprisingly, the presence of a C-terminal epitope tag affected lipid raft association and encapsidation of the A3G ... with lipid rafts, presumablyon intracellular membranes [14]. Since lipid rafts areimportant for HIV-1 assembly and release [37] we investi-gated a possible correlation between lipid raft- association and...
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Báo cáo y học: "Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc" pdf
... immunolocalization of TSP-2 in the human disc and the normal mouse disc, and sub-sequently examined mice with a targeted disruption of theTSP-2 gene with respect to the morphology and cellularity of the ... discsMorphology of collagen lamellae in the annulus of a mouse discs. The morphology was examined with Masson-trichrome stain and with polar-ized light microscopy of the same field. (a) and (b) Annulus of ... human disc, and its location in the disc and bordering soft tissues of 5-month-old normal wild-type (WT)mice and of mice with a targeted disruption of the TSP-2 gene.Immunohistochemistry and quantitative...
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Báo cáo y học: " Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes" ppsx
... immunodeficiency virus type 1 (HIV-1) -based gene delivery systems arepopular due to their superior efficiency of transduction of primary cells. However, these systemscannot be readily used for delivery of ... Research and TherapyOpen AccessResearchSubstitution of the Rev-response element in an HIV-1- based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytesNarasimhachar ... particles.Conclusion: A simple modification of an HIV-1 gene delivery system, namely, replacement of HIV-1 RRE with that of SIV, allowed efficient delivery of Rev M10 transgene into T-cell lines forintracellular...
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Báo cáo y học: "Clustering of genes into regulons using integrated modeling-COGRIM" ppsx
... page)(a)(b)(c)(d)YBL001C 4.2E-04YBL044W 1.5E-06YCL065W 8.0E-05YCL066W 8.0E-05YCL067C 8.0E-05YCR039C 4.7E-05YCR040W 4.7E-05YCR041W 4.7E-05YCR105W 1.7E-04YDL066W 1.4E-08YDR299W 1.3E-05YDR473C ... 1.5E-05YDR543C 4.8E-05YDR544C 4.5E-04YDR545W 4.5E-04YEL025C 4.7E-10YGL001C 3.5E-06YGR296W 2.0E-04YHR001W 2.5E-04YHR193C 4.1E-05YJR079W 1.4E-09YKL015W 2.9E-05YLR169W 2.7E-04YLR171W ... 2.7E-04YLR463C 2.0E-05YLR465C 2.0E-05YLR467W 2.0E-05YML088W 2.8E-04YNL337W 3.6E-07YNL338W 2.7E-06YNL339C 2.7E-06YPL270W 3.5E-04YPR190C 2.6E-05YGL187C 2.7E-12YHR051W 2.4E-12YDR529C...
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Báo cáo Y học: Properties of the Na+/H+ exchanger protein Detergent-resistant aggregation and membrane microdistribution potx
... Group,2Anatomy and 3Cell Biology, Faculty of Medicine and Dentistry,University of Alberta, Edmonton, Alberta, CanadaThe Na+/H+exchanger is a ubiquitous membrane protein of bacteria, plants and ... microdomains.Treatment of cells with methyl b-cyclodextrin had a smallstimulatory effect on Na+/H+exchanger activity and reduced the amount of Na+/H+exchanger in low densitymembrane fractions. Our study ... theNa+/H+exchanger and of caveolin, a marker of lipid rafts.To avoid possible detergent-induced artifacts that couldeither alter the distribution of the Na+/H+exchanger or theconstituency of the lipid rafts,...
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Báo cáo y học: "Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients" pps
... (both 10 ng/ml).Cytokine analysisIFN-γ and IL-4 production were analyzed by ELISA uponcostimulation with CD3/CD28 and cytokines after 5 days of culture. After both 5 and 10 days of culture, cells ... theabsence of or in the presence of IL-7 and/ or IL-4. Theproduction of IFN-γ and IL-4 was measured by ELISA and bysingle-cell FACS analysis to indicate Th1 and Th2 cellactivity. CD3/CD28 ... during (a) 5-daycultures or (b) 10-day cultures in the presence of IL-7, of IL-4, or of IL-7 and IL-4. Cytokine production of differentiated cells was analyzed uponionomycin/phorbol myristate acetate...
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Báo cáo y học: "Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus" pptx
... pathways and identifysusceptibility genes or susceptibility effects that might beepistatic, additive or independent.Similarly, the psoriasis study analyzed a region previouslyidentified by linkage ... transfection experiments with which theycould show the allelic effect of the polymorphisms ongene expression in reporter assays and their effect by co-transfection of RUNX1. In spite of these experiments, ... chondrocytes [7,36–38].A possibility exists that susceptibility to rheumatoidarthritis and part of the development of the disease mightbe related to the activity of RUNX2 in these tissues and...
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Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... twopatients with SS [6].Detailed analyses of the frequency of occurrence and mutations of the highly mutable motifs RGYW and WRCYrevealed that mutations in nonproductive VLrearrange-ments of B ... nonproductive and productive repertoires of these donors exhibited a comparable usage of Vκ and Jκas well as Vλ and Jλ gene elements [10,11].Determination of Taq polymerase fidelity and thefrequency of ... parotid gland of the SS patient. In the nonproductive repertoire of periph-eral blood and parotid gland B cells, respectively, 18.2%(4/22) and 23.5% (4/17) of all mutations were withinRGYW/WRCY motifs....
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Báo cáo y học: "Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis" pot
... conception and design of this study,carried out the cellular, molecular, and genetic studies, and drafted the manuscript. YWS was involved in the conception and design of this study and helped draft ... wasmeasured by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays and by flow cytometricanalysis after propidium iodide (PI) staining. Bcl-2 expression and signaling pathways (Akt, ... thatis rapidly induced by physical and chemical stresses. The anti-apoptotic function of Hsp70 depends on its ability to interact with protein substrates that are not always associated with thechaperoning...
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Báo cáo y học: "Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells" potx
... Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986,883:173-177.27. Le Maitre CL, Freemont AJ, Hoyland JA: Accelerated ... quantification of DNA and glycosaminogly-cans (GAG) content using the pico green assay (Invitrogen,Paisley, UK) and the dimethylmethylene blue (DMMB) assay.The beads were solubilised by incubation ... was particularly prominent in thecytoplasm of the chondrocyte-like cells of the NP and IAF, with both single cells and those in clusters showing immunopositiv-ity (Figures 1 and 2). CDMP 1...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ