... Biochem. 271) Ó FEBS 2004
Insights into the reaction mechanism of glycosyl hydrolase family 49
Site-directed mutagenesis and substrate preference of isopullulanase
Hiromi Akeboshi
1
, Takashi ... numbered
subsites. The anomeric configuration of products of both
Dex49A and IPU are identical, as well. Does the substrate
preference of the negativ...
... Examination of 50% of the data
in the SLs leads to identification of between 75%
(AdjN) and 80% (PNV) of the TPs. (ii) For the
first 40% of the SLs, and lead to the worst
results, with outperforming ... suitable for a qualitative evaluation of lexi-
cal association measures, mainly for the follow-
ing reasons: the instability of precision values ob-
tai...
... using
Ó FEBS 2004 CaM-induced conformational transition in AC (Eur. J. Biochem. 271) 823
Insight into the activation mechanism of
Bordetella pertussis
adenylate cyclase by calmodulin using fluorescence ... France
The interaction of the adenylate cyclase catalytic domain
(AC) of the Bordetella pertussis major exotoxin with its
activator calmod...
... 2035
Bacitracin inhibits the reductive activity of protein
disulfide isomerase by disulfide bond formation with free
cysteines in the substrate-binding domain
Nina Dickerhof
1
, Torsten Kleffmann
2
, ... Ruddock LW, Darby NJ & Freedman RB
(1998) The b domain provides the principal peptide-
binding site of protein disulde isomerase but al...
... overexpressing the EVH1 domain. These results indicate that
the EVH1 intrabodies inhibit only the EVH1 domain function that regu-
lates IL-2 synthesis signaling without affecting the overall domain structure
of ... bind to the target
proteins on the lumen side and inhibit transport of tar-
get proteins in the process of functional maturation
[6,8]. If...
... amplitude and duration of
signaling are controlled by the kinases or phosphatases
in the system, and whether they are controlled differ-
entially by some or all of them. On the basis of the
antagonistic ... signaling; the
final intensity of signaling; the duration of signaling
and the integral signal intensity (which corresponds to
the ‘area-under -the- curve’...
... (2002) and the references therein). Our
findings call for a greater synergy between QA and
IR in the web search context and an improved un-
derstanding of question- queries by search engines.
2 Related ... rise in the use of
Q -queries is not a direct result of users learning the
most effective query formulation for the search en-
gine. These suggest an...
... Studies on the regulatory properties of the pterin cofactor
and dopamine bound at the active site of human phenylalanine
hydroxylase
Therese Solstad
1
, Anne J. Stokka
1
, Ole A. Andersen
2
and ... fractional decrease of phos-
phorylation rate seen at the concentration x of H
4
biopterin. v
o
is the
rate in the absence of H
4
biopterin...
... mutation [19]. The G51A,
G51V and G89D mutants were studied in the context
of the folding and packing of the TM domain together
with other adRP mutations in the other TM helices
[20]. These studies ... (1996) Structure and
function in rhodopsin: correct folding and misfolding in
two point mutants in the intradiscal domain of rhodop-
sin identified in retin...
... suppresses the dynamic instability of
microtubules, activates the mitotic checkpoint and
induces apoptosis in MCF-7 cells
Mithu Banerjee, Parminder Singh and Dulal Panda
Department of Biosciences ... on the dynamic instability of
individual microtubules in MCF-7 cells
The effects of curcumin on the dynamic instability of the
in...
... injury, the greater the invasion of privacy;
and (iii) the appropriateness of consent for disclosing the
data - the less appropriate the consent, the greater the
potential invasion of privacy.
ird, ... less of the records could be correctly re-
identified by reducing the precision of the postal code to
the first three characters, and the date of bir...
... walk’ is longer before radiotherapy than
afterwards: a qualitative study questioning the
baseline and follow-up design
Elsbeth F Taminiau-Bloem
1*
, Florence J van Zuuren
2†
, Margot A Koeneman
1†
, ... Journal of Cancer 2005, 41:1679-1709.
doi:10.1186/1477-7525-8-69
Cite this article as: Taminiau-Bloem et al.: A ‘short walk’ is longer before
rad...
... purposes)
Acta Veterinaria Scandinavica
Open Access
Research
A novel and stable "two-hit" acute lung injury model induced by
oleic acid in piglets
Xiaofeng Li
1
, Yinglong Liu*
1
, Qiang ... pulmonary injury, and acute lung injury (ALI) often
results in a high mortality and financial cost in pediatric patients. Evidence has showed that oleic...
... survivors. Compares the projected power of the Improving Care
of ALI Patients (ICAP) study with that of a hypothetical cohort study
with a sample size of 80 acute lung injury /acute respiratory ... randomized trial. However,
the impact of LTVV and other critical care therapies on the
longer-term outcomes of ALI/ARDS survivors remains uncertain.
The I...
... Beta-adrenergic agonists increase alveo-
lar fluid clearance in normal lung [13-19] and in several animal
models of acute lung injury [20-22] as well as in ex vivo human
lungs [19] and in patients with ... (mean and 95% confi-
dence interval).
Figure 1
Days alive and free of acute lung injury in low dose (<2.2 mg/day) and high dose (≥ 2.2 mg/day) salbutamol...