Báo cáo khoa học: "Daily enteral feeding practice on the ICU: attainment of goals and interfering factors" ppsx

... retention of less than 200 ml and a length of stay above the median was related to improved success of feeding. Of the remaining interventions, the administration of contrast via the tube, the need ... beds. Feeding processStandard feeding practice involved the continuous administra-tion of enteral feeding solutions over 24 hours. Although astandard feeding protocol was in use (see Additional ... TISS and elective admis-sion showed an adverse effect on the success of feeding (Table 4).DiscussionWith the use of a meticulous, daily record of the ICU feeding practice we evaluated the feasibility...

Báo cáo khoa hoc:" Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210" pptx

... donor (GT) and acceptor (AG) sites, except for the splice donor sites of intron 7 (AT) and1 0 (GC). The introns sizes were between74 (intron 38) and 20198 bp (intron 1). Introns wereJournal of ... intron, and 3 kb of the upstream promoter region of mouse GP210.Similar to human, a GPC island containing 644 bp and with a GC content of 74% was found starting 268 ntupstream of the start codon ... webserver, 40 exons covering 102551 bp were defined (seeTable 1, additional file 1). The exons ranged between 63(exon 24) and 251 (exon 36) bp. All exon-intron junc-tions conformed to the consensus...

Tài liệu Báo cáo khoa học: "Enhanced word decomposition by calibrating the decision threshold of probabilistic models and using a model ensemble" pdf

... ap-proaches is based on the learning aspect during the construction of the morphological model. If the data for training the model has the same struc-ture as the desired output of the morphologicalanalysis, ... boundaries (zero-order) and the graphemic representation of the word, however, is conditioned on the length of the word mjwhich means that the probabilitydistribution is in fact Pr(bji|mj). ... subsets with the ratio of 9:1 we randomly split the data into training, validation and test sets with the ratio of 8:1:1. We then run our experiments and measured contingency table counts.Rather than...

Tài liệu Báo cáo khoa học: "Organizing Encyclopedic Knowledge based on the Web and its Application to Question Answering" ppt

... the description.For the second type of question, human examineeswould search their knowledge base for the description of each of four candidate terms. Then they wouldchoose the candidate term ... token ringIn the autumn of 1999, out of 80 questions, the num-ber of the ﬁrst and second types were 22 and 18, re-spectively.4.3 Implementing a QA systemFor the ﬁrst type of question, human ... is not only extraction but generation of ency-clopedic knowledge.Section 2 explains the overall design of our ency-clopedia generation system, and Section 3 elaborates on our organization model....

Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx

... up-regulation of hypoxia-inducible transcription factor-1a and the down-regulation of the b-oxida-tion of fatty acids, both of which could contribute to the accumulation of lipids. On the basis of ... that the degree of inter-nalization of QDs and various other NPs is dependent on their size, surface charge, concentration in the med-ium and duration of exposure [4,7–11]. We have alsoshown the ... up-regula-tion of HIF-1a, most probably via the production of ROS. QDs and the hypoxia mimetic CoCl2down-regulate the oxidation of FFAs and induce the accumulation of lipids. Further studies...

Báo cáo khoa học: C ﬁ G base mutations in the CArG box of c-fos serum response element alter its bending ﬂexibility Consequences for core-SRF recognition potx

... with the second half-site. The main difference between SREfos and SREGfos, on the one hand, and SREGGfos, on the other hand,consists in the distinct strains acting on the helix ply of these ... variationin the V2contribution of the spectral component S2.Actually, the temperature proﬁle of the V2contribu-tion is in accordance with the reduction in the bentpopulation in the oligonucleotide. ... repartitionalong the oligonucleotides and preserve the sameB-DNA conformation. Essentially, the interactions at the mutated positions are modiﬁed together with the arrangement of water molecules and...

Báo cáo khoa học: A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus potx

... and after acti-vation, the RNase A zymogen displayed high conformational stability and evasion of the endogenous ribonuclease inhibitor protein of the mammaliancytosol. Thus, the creation of ... inhibitors upon activation [2,3].If the linker merely occludes the substrate from bind-ing to the RNase A zymogens and has no inﬂuence on the conformation of active-site residues, then activationwould ... 14-residue linker, and seven disulﬁde bonds. The conforma-tional energy of the side chains of the variant residues were minim-ized with the programSYBYL (Tripos). Atoms of the linker and cysteine...

Báo cáo khoa học: DNA polymerase e associates with the elongating form of RNA polymerase II and nascent transcripts pot

... [22]. Therefore, we tested the effect of the replicative state of the cell on the interaction betweenPol e and RNA pol II. A possible conﬁnement of the interaction to late G1 and S phases (the ... initiation and execution of DNAreplication) would have strong implications on a func-tional interplay between transcription and DNA repli-cation. We therefore examined the interaction betweenRNA ... effect of local UV damage on the nuclearlocalization of RNA pol II and Pol e. The RNA pol II–Pol e interaction does not depend on DNA replicationPol e is one of the three major replicases in the...

Báo cáo khoa học: Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity pdf

... of dHANDdecreased the transcriptional a ctivity of dHAND/E47heterodimer.Fig. 6. The eﬀects of A kt expression on the transcriptional activity of dHAND. (A) AU5-d HAND, -dHAND-Ala-X, -dHAND-Ala, ... phosphoryla-tion on dimerization activity of dHAND, we next examinewhether the DNA binding activity of dHAND could beaffected by Akt phosphorylation. The inﬂuence of phos-phorylation by Akt on the DNA ... phosphorylation sites reside in the region of amino acids 103–132 of dHAND. The region of amino acids 103–132 contains severalserine and threonine residues and Ser114 matches the consensus motif...

Báo cáo khoa học: A new molecular tool for transgenic diatoms Control of mRNA and protein biosynthesis by an inducible promoter–terminator cassette docx

... completely shut off, the expression of genes that are under control of the Pnr ⁄ Tnr cassette.Decoupling of transcription and translation of gfp mRNATo further evaluate the properties of the Pnr ⁄ ... genes.Furthermore, the addition of both nitrate and appro-priate concentrations of ammonium allows, within lim-its, the control of the amount of induced protein. The observed lag phase of 1 h ... allowing observation of the protein’sinﬂuence on the progression of the cell cycle and the silica biogenesis. As the regulation of NR expressionappears to be very similar throughout the diatomrealm...

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