... assays, sheep erythrocytessensitized with rabbit anti-sheep erythrocyte antibodieswere used as target cells. The hemolytic activity wasexpressed in units/ml. One unit of hemolytic activity is defined ... protein C3 is the initial point of the alternativepathway,and,atthesametime,aconvergepointofallthree complement activation pathways, i.e. starting pointfor the terminal pathway [16-18].Hypoactivation ... proteins. It is a complex cascadeinvolving proteolytic cleavage of serum glycoproteinsoften activated by cell receptors. This cascade ultimatelyresults in induction of the antibody responses, inflam-mation,...