... combination. The singleexception is the addition of weak base (e.g. tris-hydroxymethylaminomethane) [6], which is normally absent from body fluids.ReviewClinical review: The meaning of acid–base abnormalities ... Treating acid–base abnormalities in the intensive care unit – the role of buffers. Crit Care 2004, 8:259-265.17. Mathieu D, Neviere R, Billard V, Fleyfel M, Wattel F: Effects of bicarbonate therapy ... for the SAFE Study Investigators: A comparison of albumin andsaline for fluid resuscitation in the intensive care unit. N Engl JMed 2004, 350:2247-2256.64. Liskaser F, Story DA: The acid–base...