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Báo cáo y học: "Clinical review: Noninvasive ventilation in the clinical setting – experience from the past 10 year" pps

Báo cáo Y học: Spectroscopic characterization and ligand-binding properties of chlorite dismutase from the chlorate respiring bacterial strain GR-1 ppt

Báo cáo Y học: Spectroscopic characterization and ligand-binding properties of chlorite dismutase from the chlorate respiring bacterial strain GR-1 ppt

... Electronspinresonancestudyoftheroleofnitricoxideandcatalaseintheactivation of guanylate cyclase by sodium azide and hydro-xylamine. Modulation of enzyme responses by heme proteins and their nitrosyl derivatives. ... wepresent the EPR spectroscopic and redox properties of GR-1 chlorite dismutase. Furthermore, we investigated the binding of hydroxide and imidazole to the ferric enzyme and of NO to the ferrous enzyme ... oxoferryl species and hypochlorite. The reaction mechanism of WF10 with hemoproteins may besimilar to the enzymatic reaction of chlorite with chlorite dismutase. Thus, the study of chlorite dismutase...
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Báo cáo Y học: Role of histidine 42 in ascorbate peroxidase Kinetic analysis of the H42A and H42E variants pptx

Báo cáo Y học: Role of histidine 42 in ascorbate peroxidase Kinetic analysis of the H42A and H42E variants pptx

... clearly active againstbothL -ascorbate and guaiacol) and has been notedpreviously for the H42E [49,50] and H42A and H42V [51] variants of HRP. These data suggest that the distal histidine residue ... in uen-tial in defining the stability of Compound II. The replacement of the distal histidine residue by alanineor glutamic acid clearly has a profound in uence on the ability of the rAPX enzyme to ... hydrogen-bond-ing structure involving the Ne of His42 and the ferryloxygen. However, although hydrogen-bonding interactions of this kind have been structurally confirmed for the ferrous-oxy...
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Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot

Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot

... T. Sumimoto (Eur. J. Biochem. 269) Ó FEBS 2002 Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu ... Structural and functional analysis of the riboflavin synthesis genes encoding GTPcyclohydrolase II (ribA), DHBP synthase (ribBA), riboflavinsynthase (ribC), and riboflavin deaminase/reductase (ribD)fromHelicobacter ... Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetaseencoded by ribC.J.Bacteriol.180, 950–955.5860 S. Kasai and...
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Báo cáo y học: "Atherosclerotic disease is increased in recent-onset rheumatoid arthritis: a critical role for inflammation" ppsx

... arthritis inflammatory activityCoassociation of carotid intima media thickness, age and rheumatoid arthritis inflammatory activity. The carotid intima media thickness (cIMT) was measured in 37 rheumatoid ... not for citation purposes)Vol 9 No 6Research articleAtherosclerotic disease is increased in recent-onset rheumatoid arthritis: a critical role for inflammationSuad Hannawi1, Brian Haluska2, ... [18].Examination and analysis of the cIMT and plaque were per-formed by the same investigator (SH).Statistical analysisContinuous variables are described as the mean ± standarddeviation, and categorical...
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Báo cáo y học: "Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients" doc

... 2.6-fold increase in miR-146a expression and a 1.8-foldincrease in miR-155 expression. Because of the invasivenessinvolved in collecting samples, monitoring miRNA expression in RA synovial tissue ... prednisone, mycophenolate mofetilSjS1 Female 30 Hydroxychloroquine, mycophenolate mofetilSjS2 Male 21 HydroxychloroquineSSc1 Female 57 Cyclosporine, hydroxychloroquine, prednisone, mycophenolate ... very exciting that two independent studies haveshown increased miRNA expression in RA synovial tissue,analyzing miRNA expression in patient PBMCs presents a dis-tinct advantage over analyzing...
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Báo cáo y học: "Platysma motor branch transfer in brachial plexus repair: report of the first case" pot

... purposes)Journal of Brachial Plexus and Peripheral Nerve InjuryOpen AccessCase report Platysma motor branch transfer in brachial plexus repair: report of the first caseJayme Augusto Bertelli*Address: ... AbstractBackground: Nerve transfers are commonly employed in the treatment of brachial plexus injuries. We report the use of a new donor for transfer, the platysma motor branch. Methods: A patient ... period of only 3 years, which may be a shortinterval for cortical integration of the hypoglossal to the musculocutaneous nerve transfer. The current study con-trolled the patient for 8 years...
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Báo cáo y học: " b-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryo" docx

... Access b-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryosYi-Ting Wu1, Che Yi Lin1, Ming-Yuan Tsai2, ... cell death of erythrocytes and the endocardium in zebrafish embryos by b-lapachone ismediated through an NQO1- and calcium-dependentpathway The linear arrangement of the ventricle and atrium and the ... erythrocyte-deficiency in circulation and heart- looping defect phenotypes in b-lapachone- treated embryos. These resultssuggest that the induction of apoptosis of endocardium and erythrocytes by b-lapachone...
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Báo cáo y học: " Foot and ankle surgery in Australia: a descriptive analysis of the Medicare Benefits Schedule database, 1997–2006" potx

... CentralPage 1 of 10(page number not for citation purposes)Journal of Foot and Ankle ResearchOpen AccessResearch Foot and ankle surgery in Australia: a descriptive analysis of the Medicare Benefits ... epidemiology and costs of foot and ankle surgery in Australia using data rou-tinely tracked by the Medicare Benefits Schedule (MBS) database, in order to inform future planning of foot sur-gery provision. ... surgery in Australia is heavily subsidisedby Medicare, a universal healthcare system financedthrough income tax and an income-related Medicare levy.Governed by the Australian Health Care Agreementsbetween...
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Báo cáo y học: "Catheterization and embolization of a replaced left hepatic artery via the right gastric artery through the anastomosis: a case report" pdf

... this article as: Miyazaki et al.: Catheterization and embolization of a replaced left hepatic artery via the right gastric artery through the anastomosis: a case report. Journal of Medical Case ... CAS E REP O R T Open AccessCatheterization and embolization of a replaced left hepatic artery via the right gastric artery through the anastomosis: a case reportMasaya Miyazaki*, Kei ... with a microcatheter and microcoils via the right gastric artery through the anastomosis.Conclusion: A replaced left hepatic artery arising from a left gastric artery can be catheterized via a right...
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Báo cáo y học: " Neurogenic diabetes insipidus presenting in a patient with subacute liver failure: a case report" ppsx

... fixeddilated pupils and supratentorial cerebral edema with maximal therapy, normal ICP, and no surgically treata-ble intracranial pathology on a background of subacute fulminant liver failure. ... characterized by changes in cerebral bloodflow, cerebral edema and intracranial hypertension. Cer-ebral blood flow may increase in patients with fulminanthepatic failure because of gradual cerebral arteriolarvasodilatation ... edema is very poor [4].Cerebral edema in patients with fulminant liver failureis a characteristically cytotoxic edema resulting primarilyfrom astrocyte swelling. This was demonstrated in ourpatient...
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Báo cáo y học: " Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model" ppsx

... AccessResearch Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse modelGuan-Hong Shang*1, Dian-Jie Lin2, Wei Xiao1, Chong-Qi Jia3, Yu Li1, Ai-Hua Wang1 and ... Thus,delayed release of HMGB1 can participate in the down-stream development of lung injury, and HMGB1 may bea distal mediator of acute inflammatory lung injury. Ethyl pyruvate (EP), a very simple ... Intratrachealadministration of HMGB1 produced acute inflammatory lung injury, and anti-HMGB1 Abs decreased the migra-tion of neutrophils to the lungs as well as lung edema in endotoxin-induced acute lung inflammation...
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Báo cáo y học: "Measurement of endotoxin activity in critically ill patients using whole blood neutrophil dependent chemiluminescence" pps

... blood from critically ill patients. In a subset of 15 patients with ele-vated endotoxin levels, as assayed using the EAA, polymyxinB – a specific endotoxin- binding agent – eliminated ormarkedly attenuated ... detecting endotoxin in whole blood based on the detection of enhanced respiratory burst activity in neutrophils followingtheir priming by complexes of endotoxin and a specific anti- endotoxin antibody ... dose to maintain systolic blood pressure > 90 mmHg).Assay of endotoxin by endotoxin activity assayThe EAA assay is described in detail elsewhere [22]. Briefly,a 2-ml sample of whole blood was...
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Báo cáo y học: "Science review: Genetic variability in the systemic inflammatory response" pdf

... depending on the outcome of interest.Interleukin-1ααand interleukin-1ββIL-1, a potent proinflammatory cytokine released bymacrophages, also plays a key role in mediating endotoxinlethality ... proinflammatory cytokines, and anti-inflamma-tory cytokines (Table 1). The outcome of an inflammatory response is dictated by avariety of factors, including the pathogenicity and duration of the stimulus, ... differences in inflammatory proteins associated with different phenotypic presentations of systemic inflammation. Basic genetic terminology is defined. Implications of genetic influences on the inflammatory...
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Báo cáo y học: " Positive end-expiratory pressure in acute respiratory distress syndrome an old yet mysterious too" pps

... ofintravascular fluid volumes is required to maintain cardiacCommentary Positive end-expiratory pressure in acute respiratory distress syndrome an old yet mysterious toolEnrico Calzia1and ... forpatients with acute lung injury or ARDS [7] increasinglyrecommend fairly high levels of PEEP. In view of this, anydata that may improve our understanding of the benefits anddangers of PEEP ... of positive end-expiratory pressure (PEEP)into the practice of mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) [1] was amongthe most important milestones in...
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Báo cáo y học: "Ethics review: Long-term outcomes and clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort study" pptx

... clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort studyJan O Friedrich1,2,3, Gail Wilson1 and Clarence Chant1,41Critical Care Department, ... unit (ICU) patients.The purpose of this study was to identify long- term outcomes after hospital discharge and readily available clinical predictors of hospital mortality for patients requiring ... with hospital mortality in very long stay patients. The informationrequired to determine whether each of these factors is appli-cable to a particular patient is readily available to clinicians.Hospital...
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