Báo cáo khoa học: "Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants" pptx
... iNO therapy, and the present study
suggests that iNO may influence clinical outcomes as well.
This should be a consideration in our armamentarium in the
battle against AHRF. The recognition that ... effect on mortality” [13].
The concern in the neonatal literature that iNO may induce
intracranial bleeding in preterm infants was not supported in
this study. Distur...
... probably
occurred in two of our previous studies [4,23]. Another rea-
son for determining the inspiratory NO concentration in this
way was the method of NO administration used. Continu-
ous administration ... decrease in MPAP
and an increase in PaO
2
/FiO
2
in the range of 0.15 to 150
ppm inhaled NO.
Toxic effects of increasing concentrations of inhaled NO
As shown in T...
... collected 10 min after the final
ααHb infusion. Inhaled NO, in concentration of 5 ppm, was
then administered for 10 min and data were recorded. The
inhaled NO was discontinued for 10 min, after which ... USA.
Abstract
Background: In order to test the hypothesis that inhaled nitric oxide (NO) reverses the pulmonary
hypertension induced by αα-diaspirin crosslinked hemoglobin (ααHb...
... 2h
of INO therapy in 61.1% of the responders, and the
remaining responded gradually during the INO treatment.
However, OI and a/A ratio remained almost the same
throughout the treatment in the non-responders ... Tolazoline was
unsuccessfully attempted in two neonates in the referring
hospitals. Methemoglobin and nitrogen dioxide were
maintained below 5% during INO therap...
... short interfering RNA (siRNA) in human cells. Both
HO-2 mRNA and protein are expressed in the eight human cancer cell
lines examined, and HO-1 expression is detectable in five of the cell lines,
including ... and
HO-2 proteins. The intensity representing HO-1 or HO-2 protein was normalized with respect to the intensity of the b-actin signal. The ratio
of each normalized value...
... calcium
channels and may thereby reduce the serotonin-
induced sustained increase in [Ca
2+
]
i
, as has been
shown for endothelin-1-induced Ca
2+
increase in Rat1
cells [29]. Whether HEK293 cells express ... (F340) increases, whereas the
fluorescence intensity at 380 nm (F380) decreases upon
the binding of Ca
2+
. The change in the ratio of
F340 ⁄ F380 determined the change...
... it
remained at 0.98 in Finland. By increasing the sensitivity
ofthesurveillanceinrodentsinSwedentothesame
level as in Finland, the annual sensitivity of this surveil-
lance system component increased ... 1. The prior probability that the
country is in fected at the beginnin g of y+1isgivenby
the function [15]:
PriorPInf PostInf PIntro PostPInf PIntro
yyy yy
11 1
(...
... extents in the FNR–FMN subdo-
main interface, including the interface in NOS (Fig. 8).
Point mutations that neutralize charge pairing or intro-
duce charge-repelling interactions may increase the
Fig. ... autoinhibitory insert elements, or elsewhere in
the enzyme.
Changing the set point for K
eq
A may in uence
electron flux through the NOS flavoprotein in interest-
ing ways...
...
that
the
frequencies
of
as
,-Cn
O
were
0.05
in
Alpine
and
0.03
in
Saanen.
Because
in
their
data
a
S1
-Cn
D
was
not
distin-
guished
from
as
,-Cn
O,
these
values
in
fact ...
is
the
seventh
allele
identified
at
the
goat
as!!asein
locus.
Its
frequency
in
the
large
Alpine
herd
of
Moissac
(N
=
198)
was
0.025.
It
was
also
observed
in
t...