... synthase. Circulation 2000, 101:931-937.85. Shindo T, Kurihara H, Maemura K, Kurihara Y, Kuwaki T, IzumidaT, Minamino N, Ju KH, Morita H, Oh-hashi Y, Kumada M, KangawaK, Nagai R, Yazaki Y: ... theprincipal activator of the extrinsic coagulation pathway, and assuch is responsible for an intravascular procoagulant state.Taylor and coworkers concluded that sustained injury to thevascular ... demonstrate that ECsurface modification occurs easily and rapidly [5,6], with ECsbeing detached from the internal elastic lamina with an indica-tion of subendothelial oedema. As early as 15 min after...