Báo cáo y học: " International perspectives on intensive care at the end-of-life: the futility movement seems alive and well" ppt

... [3]. What this book adds to these important issuesis that it demonstrates considerable variability in the rationales toward application of the principle of medical futility, and variation in the ... survival for that patient’ [4], and reasoned that such therapy could reasonably bewithheld without consent from patients or their families.Several years later, the Society for Critical Care Medicinecame ... the futility movement based on these arguments [11]. The book editedby Crippen and colleagues provides persuasive, albeitanecdotal, evidence that declaration of the ‘death’ of the futility...

Báo cáo y học: "Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study" pptx

... site of resuscitation or in the ambulance.ConclusionsThis observational cohort study demonstrates that spon-taneous hypothermia on ICU admission after resuscita-tion for primary cardiac arrest ... contributionsAdH and LR retrieved the data and built the database. AdH performed the analysis and wrote the manuscript drafts. ACdP designed the study and coached the analysis. JB performed the statistical ... performed.A limitation of our study is that we did not record the interval between circulatory arrest and return of sponta-neous circulation, the parameter repeatedly identified asa strong outcome...

Báo cáo y học: "Early tracheostomy in intensive care trauma patients improves resource utilization: a cohort study and literature review" pdf

... intubation often requires the administration of systemic sedation, with attendant compli-cations. Finally, the incidence of ventilator-associated pneu-monia is related directly to the duration ... 157 eligible patients, only 112 completed the study because of physician bias and incomplete information; and only 14 patients entered the second randomization. ICU, intensive care unit; LOS, ... curves of the duration of mechanical ventilation in early and late tracheostomy groupsKaplan–Meier curves of the duration of mechanical ventilation in early and late tracheostomy groups. Early tracheostomy...

Báo cáo y học: " International symposium on peripheral nerve repair and regeneration and 2nd club Brunelli meeting" pdf

... regenera-tion, biomaterials and artificial conduits for nervereconstruction, and clinical applications, such as tubuli-zation and end-to-side neurorrhaphy. The international and multidisciplinary panel ... interest, the International Sym-posium "Peripheral Nerve Repair and Regeneration and 2nd Club Burnelli Meeting" was held at the Departmentof Animal and Human Biology of the University of Turin,Italy, ... nerve repair and regen-eration has increased significantly over the last twentyyears since, while in the past most nerve traumas and dis-eases were not surgically treated, today the number ofnerve...

Báo cáo y học: "Clinical observations on intensive immunosuppressive therapy combined with umbilical cord blood support for the treatment of severe aplastic anemia" ppt

... efficacy rate was 88%. The median follow-up time was 35 months (range13-47 months), and the 3-year overall survival rate was 92%. Patients rapidly achieved reconstitution ofhematopoiesis. The ... ignored. Intensive immunosup-pressive therapy, such as combined anti-thymocyteglobulin (ATG) and cyclosporine (CSA), has an averageonset of efficacy of 3-7 months and an efficacy rate of60-80%. ... however, the recovery ofhematopoiesis is slow, and some studies have demon-strated high treatment-related mortality rates. Therefore, the toxic side effects of high-dose CTX (e.g., hemorrha-gic cystitis)...

Báo cáo y học: "New perspectives on an old disease: proteomics in cancer research" pdf

... quantifying changes in proteinphosphorylationCell signaling is often mediated by post-translationalmodifications that modify protein conformation, localiza-tion, activity and stability. Generally, ... strategy, further demonstrated by Ruedi Aebersold (also at the Institute for Molecular Systems Biology), that alleviatessome of the current limitations. The first step consists of the in-depth ... Using a hydrazide-based chemistry toselectively enrich for N-linked glycopeptides by affinitypurification, a 20-fold reduction in sample complexity wasachieved. Many of the glycosylated proteins...

Báo cáo y học: "European Society of Intensive Care Medicine 14th Annual Congress, 30 September–3 October 2001, Geneva, Switzerland" docx

... program, and 28 for the nursing and physiotherapy ses-sions. The 3-day program included 39 thematic sessions, 72sessions dedicated to oral or poster presentations ofabstracts, and nine educational ... indicate thatpretreatment with itraconazole, anisodamine, and ramiprilattenuated the severity of endotoxin-induced pulmonaryinflammatory response, namely via a decrease in the produc-tion of interleukin-1.Ethics The ... permission and modifications from the Investigational Drugs Database (http://www.iddb3.com)Abstract The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basicscientists...

Báo cáo y học: "Variability science in intensive care – how relevant is it" docx

... automated and sophisticated variabilityparameters are yet available for application in the critically ill. The investigator must always verify the data beforecomputing the variability estimates. ... variability decreases. Even low-frequencyvariability in heart rate – a parameter that traditionally wasconsidered a marker of sympathetic activity in conditions ofCommentaryVariability science in intensive ... health. Heart ratevariability is maximal when there is full interplay between vagal and sympathetic drive to the sinus node. In severe heartfailure vagal activity is absent and sympathetic drive...

Báo cáo y học: "Early identification of intensive care unit-acquired infections with daily monitoring of C-reactive protein: a prospective observational study" pot

... antibiotic therapy couldeventually be withheld in the absence of a strong clinical sus-picion of infection.Conclusion The data of the present study indicate that daily CRP determi-nations could ... CRP and WCC weremeasured at admission and then daily until discharge or death. The temperature was evaluated hourly and daily extreme val-ues were recorded. Patients were evaluated daily for ... 0.001).Conclusion Daily CRP monitoring and the recognition of the CRP pattern could be useful in the prediction of ICU-acquiredinfections. Patients presenting maximum daily CRP variation>4.1...

Báo cáo y học: "Frontal EEG for intensive care unit sedation: treating numbers or patien" pptx

... additionally improved one-yearsurvival, the effect probably depending on a lesser likelihoodof oversedation [8]. Modifying sedation regimens may alsomodify patients memory panorama from the ... in critically ill patients needingsedation. A major underlying problem in applying EEG monitors in the ICU is that they have been developed for measuring anestheticdepth and the related risk ... titrating sedation in the critically ill. Despite many attempts, no study has yet presenteddata showing improved outcome with the use of EEG monitors inICU sedation. Meanwhile, clinical sedation protocols...

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