Báo cáo khoa học: "The index herd with PMWS in Sweden: Presence of serum amyloid A, circovirus 2 viral load and antibody levels in healthy and PMWS-affected pigs" ppsx

... that remained healthy seroconverted to PCV2as the viral load was increased, regardless of initially having low or high levels of PCV2-antibodies.Conclusion: In this index case of PMWS in Sweden, ... necropsies in Increase in serum antibody levels to PCV2 in comparison to when a viral load of 107 was measured in serum for the first time in pigs of different health and antibody statusFigure 4Increase ... (Table 2) , the wasting coincided in time with serum levels of PCV2 exceeding 107 per ml. None of these pigs showed aclear seroconversion to PCV2 in relation to this increased serum load of PCV2...

Tài liệu Báo cáo khoa học: "The Arabic Online Commentary Dataset: an Annotated Dataset of Informal Arabic with High Dialectal Content" pdf

... on Creating Speech and Language Data With Amazon’s Mechanical Turk, pages 108–113.Yun Lei and John H. L. Hansen. 20 11. Dialect clas-siﬁcation via text-independent training and testing forarabic, ... exists forLevantine within Al-Ghad sentences, and for Gulfwithin Al-Riyadh sentences.Using those two criteria, there is a very cleardistinction between Workers who are faithful and those who ... NaturalLanguage Processing. Morgan & Claypool.Ann Irvine and Alexandre Klementiev. 20 10. Using Me-chanical Turk to annotate lexicons for less commonlyused languages. In Proceedings of the NAACL...

Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes doc

... cooperates with ESE-1 in transactivating the iNOS promoter in endo-ABFig. 3. ESE-1 binds to several Ets sites in the COX -2 promoter. (A) Interaction of ESE-1 with Ets binding sites in the COX -2 promoter. ... expression within 1 h of exposure,reaching a peak at 4 h and leveling off after 24 h [ 12] .To investigate the level of ESE-1 protein followingLPS exposure, we performed western blot analysis in murine ... TC ⁄ 28 a2 cells were infected with adenovirus for 1 h in serum- free medium using a multiplicity of infection of 300. After infection the cells were washed with medium and incubated for 16 h in...

Báo cáo khoa học: The protein shufﬂe Sequential interactions among components of the human nucleotide excision repair pathway pdf

... domain of the human DNA repair proteinhHR23B. Febs J 27 2, 24 67 24 76.11 Kamionka M & Feigon J (20 04) Structure of the XPCbinding domain of hHR23A reveals hydrophobicpatches for protein interaction. ... protein–protein and protein–DNA interac-tions must occur in the appropriate order. For exam-ple, XPC interacts with the p 62 subunit of TFIIH and, in turn, p 62 interacts with XPG. The results of ... direct con-tact with the XPC. The DNA-binding domain of XPCoverlaps with its hHR23B interaction domain [ 12] .However, a dearth of structural information for thehHR23B-binding site of XPC makes...

Báo cáo khoa học: The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding A possible mechanism for its antiproliferative activity Manu Lopus and Dulal Panda docx

... antiproliferativeactivities of this alkaloid [22 28 ]. Further, it has beenshown that sanguinarine binds to tubulin, and thisinhibits the binding of colchicine to tubulin [29 ]. In addition, sanguinarine has been ... reversed, indicating that high concentrations of sanguinarine induced aggregation of tubulin in the presence of MAPs. Electron micrographs of polymersformed in the absence and presence of 20 , 50 and 100 ... sanguinarine. Arrows indicate thebundling of interphase microtubules.Antiproliferative mechanism of action of sanguinarine M. Lopus and D. Panda 21 42 FEBS Journal 27 3 (20 06) 21 39 21 50 ª 20 06 The...

Báo cáo khoa học: The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism docx

... at4.10 p.p.m., which is assigned to 22 -OH, has three cor-relations in the COSY spectrum: they are 22 (OH) to 22 -CH, 22 (OH) to 23 -CH 2 and 22 (OH) to 24 -CH 2 .Additional conﬁrmation was provided ... arelabeled with * in the 1D proton spectrum. (B)1H-1H COSY. Theline indicates the correlations of 22 -OH proton to protons at C 22, C23 and C24.A. Slominski et al. P450scc hydroxylates vitamin D3FEBS ... at C -22 (Fig. 5). The signiﬁcantaccumulation of 20 (S)-hydroxyvitamin D3 (Fig. 1A)indicates easy release from the active site of theenzyme with only a minor portion remaining (orrebinding)...

Báo cáo khoa học: The Janus-faced atracotoxins are speciﬁc blockers of invertebrate KCa channels ppt

... 5,5Æ7, pp. 22 1 23 8. Elsevier,Oxford. 20 Swartz KJ (20 07) Tarantula toxins interacting with volt-age sensors in potassium channels. Toxicon 49, 21 3 23 0. 21 Hanner M, Schmalhofer WA, Munujos ... incorporating a cys-tine knot and a triple-stranded b-sheet in toxic and inhibitory polypeptides. Protein Sci 3, 1833–1839.3 King GF, Tedford HW & Maggio F (20 02) Structure and function of insecticidal ... weighing 9 20 mg were injected with 1 2 lL of toxin diluted in insect saline [44] at a concen-tration range of 10–106 pmolÆg)1. Each test dose was admin-istered to 10 ﬂies and performed in...

Báo cáo khoa học: The chromosomal protein HMGN2 mediates lipopolysaccharide-induced expression of b-defensins in A549 cells potx

... dose-dependentupregulation of HBD -2 mRNA and protein expression in Caco -2, HT -29 and SW480 cells [ 42] . This is paral-leled by changes in the acetylation of distinct core pro-teins, H4 and HMGN2, resulting in the induction ... pSilencer-HMGN2 -2; siRNA2, small interfering RNA2; TNF -a, tumour necrosis factor a; TSA, trichostatin. 21 52 FEBS Journal 27 8 (20 11) 21 52 21 66 ª 20 11 The Authors Journal compilation ª 20 11 FEBSAmong ... ampliﬁcation of the corresponding part of HMGN2 cDNA). In A549 cells, replenishment of HMGN2 protein upregu-lated the protein levels of HBD -2, an indication thatthe levels of this protein are indeed linked...

Báo cáo khoa học: The ferredoxin-NADP+ reductase ⁄ferredoxin electron transfer system of Plasmodium falciparum docx

... upon ligand binding, is indicated. The FAD-binding and the NADP-binding domains of the protein are shown in yellow and blue, respectively. (B) Ribbon model of the dimeric form of PfFNR(Protein Data ... of PfFNR. PfFNR ( 15 lM) was incubated at 20 °C in the presence of 0.5 mM H 2 O 2 in 50 mM Tris ⁄ HCl (pH 7.4) containing10% glycerol. (A, B) The progress of protein dimerization either in the ... proteinsemploying deazariboﬂavin as catalyst. J Biol Chem 25 2,56 12 5614.36 Pennati A, Razeto A, de Rosa M, Pandini V, VanoniMA, Mattevi A, Coda A, Aliverti A & Zanetti G (20 06) Role of the His57-Glu214...

Báo cáo khoa học: The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the ﬁrst two steps in arginine biosynthesis potx

... in this work.Plasmids Cloning vectorOrigin of insert Nature of insert Expressed proteinpYB2 pYX213 (2l, URA3) S 127 8b PromoterGAL ò ARG2 ORF-HAtag ( 32) WT NAGS-HApYB3 pYX 223 (2l, HIS3) S 127 8b ... assayed in the presence of increasingarginine concentrations. The results are presented in Fig. 6. In extracts of KA44(pYB2 + pYB3), the wild-typekinase proved to be sensitive to arginine inhibition. ... medium(containing 3% glucose). Arginine starved cells wereinitially grown on medium containing arginine, centrifuged,washed with water and resuspended in M.am mediumwithout arginine. Cells...

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